Actinomadura graeca: AGRA3207_002370
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Entry
AGRA3207_002370 CDS
T07938
Name
(GenBank) ketosynthase chain-length factor
KO
K05552
minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-
2.3.1.260
2.3.1.235
]
Organism
agra
Actinomadura graeca
Pathway
agra00253
Tetracycline biosynthesis
agra01056
Biosynthesis of type II polyketide backbone
agra01100
Metabolic pathways
agra01110
Biosynthesis of secondary metabolites
Module
agra_M00778
Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:
agra00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01056 Biosynthesis of type II polyketide backbone
AGRA3207_002370
00253 Tetracycline biosynthesis
AGRA3207_002370
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
agra01004
]
AGRA3207_002370
01008 Polyketide biosynthesis proteins [BR:
agra01008
]
AGRA3207_002370
Enzymes [BR:
agra01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.235 tetracenomycin F2 synthase
AGRA3207_002370
2.3.1.260 tetracycline polyketide synthase
AGRA3207_002370
Lipid biosynthesis proteins [BR:
agra01004
]
Polyketide synthase
Component type
AGRA3207_002370
Polyketide biosynthesis proteins [BR:
agra01008
]
Polyketide synthase (PKS)
Type II PKS
C7-C14 cyclized polyketide type
Octaketide PKS
AGRA3207_002370
Nonaketide PKS
AGRA3207_002370
Decaketide PKS
AGRA3207_002370
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Ketoacyl-synt_C
Motif
Other DBs
NCBI-ProteinID:
QXJ21511
LinkDB
All DBs
Position
complement(2713096..2714322)
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AA seq
408 aa
AA seq
DB search
MRARRAVITGLGVVAPTGIGVTGHWEATLAGDCRIAPVRDFDASALPVRLAGQVEGFEHS
EFVENRLAVQTDRWTWMALAATQLGLVDAALDPAKEDPFKLSVLTASASGGNAFGQREIQ
ALWKDGPRQVSAYQSIGWFYAASSGQISIKHKLKGACGVLVADAAGAVDALAAARRQIRR
GLAAVVTGGTEAPLSPYALACQSGTGALSGETDPARAYRPFAADATGHVPGEGGAMLVVE
EQAHARRRGAPQVYAEVAGTASTHDAFHVTDAAPDHGQLARAMRLALDRAGVAPDGVGAV
FADGAGVPESDRLEAAALREVFGPRRVPVTVPKTMTGRLCSGGAALDLAWAAQALSTGII
PPSVNLDGRDDLDLVTSPREAPGLSAVLVVARGAGGFNSAAVLRTPDD
NT seq
1227 nt
NT seq
+upstream
nt +downstream
nt
atgagggcccgccgcgccgtcatcaccggcctcggcgtcgtcgcgccgaccggcatcggc
gtcaccgggcactgggaggcgacgctggcgggcgactgccggatcgcgcccgtccgcgac
ttcgacgcctccgcgctgccggtgcgcctcgccgggcaggtcgaggggttcgagcactcg
gagttcgtcgagaaccggctcgccgtccagaccgaccggtggacgtggatggccctcgcg
gccacccagctcgggctcgtcgacgccgcgctcgacccggcgaaggaggacccgttcaag
ctgtcggtgctgacggcgagcgcgtccggcggcaacgccttcgggcagcgggagatccag
gcgctgtggaaggacggcccccgccaggtgagcgcctaccagtcgatcggctggttctac
gcggcgagcagcggccagatctccatcaagcacaagctcaagggcgcctgcggcgtgctg
gtggccgacgccgccggggccgtggacgcgctggccgcggcgcgccggcagatccgccgg
gggctcgcggcggtggtgaccggcggcaccgaggcgccgctgtcgccgtacgcgctggcc
tgccagtccggcacgggcgcgctgagcggggagaccgaccccgcccgcgcgtaccgcccg
ttcgccgccgacgccacgggccacgtgccgggggagggcggcgcgatgctcgtcgtcgag
gagcaggcacacgcccgccgccgcggcgcgccgcaggtgtacgccgaggtcgccggcacc
gcctccacccacgacgcgttccacgtcaccgacgccgcgcccgaccacgggcagctcgcg
cgggcgatgcggctggccctcgaccgcgccggcgtcgcgccggacggcgtcggcgccgtc
ttcgccgacggcgcgggcgtccccgagtccgaccggctggaggccgccgcgctgcgcgag
gtgttcgggccgcggcgggtcccggtgacggtgccgaagaccatgaccgggcgcctgtgc
tccggcggcgccgccctcgacctggcctgggccgcgcaggcgctgagcaccgggatcatc
ccgccctcggtgaacctggacgggcgggacgacctggacctggtcacctccccgcgggag
gcgcccgggctctccgccgtcctcgtggtggcgcgcggcgccgggggcttcaactccgcg
gccgtcctcaggacgcccgatgactga
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