KEGG   Acinonyx jubatus (cheetah): 106983476
Entry
106983476         CDS       T04657                                 
Name
(RefSeq) steroid 21-hydroxylase isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
aju  Acinonyx jubatus (cheetah)
Pathway
aju00140  Steroid hormone biosynthesis
aju01100  Metabolic pathways
aju04925  Aldosterone synthesis and secretion
aju04927  Cortisol synthesis and secretion
aju04934  Cushing syndrome
Module
aju_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:aju00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    106983476
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    106983476
   04927 Cortisol synthesis and secretion
    106983476
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    106983476
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:aju00199]
    106983476
Enzymes [BR:aju01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     106983476
Cytochrome P450 [BR:aju00199]
 Cytochrome P450, animal type
  CYP21 family
   106983476
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 106983476
NCBI-ProteinID: XP_026913883
UniProt: A0A6J1Z9Z1
LinkDB
Position
B2:complement(119242090..119247873)
AA seq 492 aa
MLLLGLLLLTALAGARLLWNKWKYRSLHLPPLAPGFLHLLQPNLPIYLLGLTQKLGPVYR
LRLGLQDVVVLNSKRTIEEAMIRRWVDFAGRPQMPSYKLVSQPYQDLSLGDYSLLWKAHK
KLTRSALLLGIRNSMEPLVEKLTQEFCERMRAQAGTPVAIQKEFSFLTCSVICCLTFGDK
EDTLVHAFHDCVQDLMKSWEHWSIQVLDIVPFLRFFPNPGLRRLKQALENRDRIVEKQLK
QHKDSMVAGQWRDMTDYMLQGMGKPRAEKGHGRLLEGHVHMSVVDLFIGGTETTATTLSW
AVAFLLHHPEIQQRLQEELDCELGPGDSGSRVPLKDPSRLPLLTATIAEVLRLRPVVPLA
LPHRTTRHSSILGYDIPEGTVVIPNLQGAHLDDTVWEQPHEFRPDRFLVPGASPRVLAFG
CGARVCLGEPLARLELFVVLARLLHAFTLLPPTGPLPSLRPRSHRGINLTMQPFQVRLQP
RGAVAPGPSQHQ
NT seq 1479 nt   +upstreamnt  +downstreamnt
atgctactccttgggctgctgctgctgaccgcgctggccggcgcccgcctgctgtggaac
aagtggaagtacagaagcctccacctcccacctcttgccccaggcttcctacacctgctg
cagcccaaccttcccatctatctgcttggtctgactcagaaactgggccctgtctatagg
ctccgcctcgggctgcaagatgtggtggtgctgaactctaagaggaccattgaggaggcc
atgatcaggagatgggtggactttgctggcagaccccagatgccctcctataagctggta
tctcagccctaccaggacctctcactaggggactattccctgctctggaaggctcacaag
aaactcacccgctcagccctgctgctgggcatccgcaactccatggagccactggtggag
aagctgacccaggagttctgtgagcgcatgagagcccaggccggcacccctgtggccatc
cagaaggagttctctttcctcacctgcagtgtcatctgttgcctcacctttggagacaag
gaggacaccttagtacatgcctttcatgactgtgtccaagatttgatgaaaagctgggag
cactggtccatccaagttttggacatagttccctttctcaggttcttccccaacccaggc
ctccggaggctgaagcaggccttggagaacagggaccgcattgtagagaagcagctgaag
cagcacaaggacagcatggtggcaggccagtggagggacatgaccgactacatgctccaa
gggatggggaagccaagagcggaaaagggccatggacggctccttgaaggacacgtgcat
atgtctgtggtggaccttttcattggtggcactgagaccacagcgaccaccctctcctgg
gctgtggcgttcttgcttcaccaccctgagattcagcagcgactgcaggaggagctggac
tgtgaactgggccctggggattcaggctcccgagtcccactcaaagacccttcacggctg
cccttgctcaccgccaccatcgctgaagtgctgcgcctgcggcctgttgtgcccctggcc
ctgcctcaccgcaccacgcggcatagcagcatcttaggctacgacatccccgagggcacg
gttgtcatccccaacctgcaaggcgcccacttggacgacacagtctgggagcagccacat
gagttccggccggatcgtttcctggtcccaggcgccagcccgagagtgctggcctttggc
tgcggagcgcgagtgtgcctgggtgagccgctggcacgccttgagctctttgtggtgctg
gcgcggctgctccacgccttcacgctgctgccccccacgggcccgctgccctctctgcga
cccaggtcccaccgtggcatcaacctcacaatgcagcctttccaggtgcggctgcagccc
cggggagcagtggccccggggccaagccagcaccagtga

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