KEGG   Astyanax mexicanus (Mexican tetra): 103027852
Entry
103027852         CDS       T05042                                 
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
  KO
K00070  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Organism
amex  Astyanax mexicanus (Mexican tetra)
Pathway
amex00140  Steroid hormone biosynthesis
amex01100  Metabolic pathways
Module
amex_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
amex_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
amex_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:amex00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103027852 (hsd3b1)
Enzymes [BR:amex01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     103027852 (hsd3b1)
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     103027852 (hsd3b1)
SSDB
Motif
Pfam: 3Beta_HSD Epimerase NAD_binding_4 Polysacc_synt_2 GDP_Man_Dehyd NAD_binding_10 KR NmrA
Other DBs
NCBI-GeneID: 103027852
NCBI-ProteinID: XP_007255664
Ensembl: ENSAMXG00000042151
UniProt: A0A8B9J7I9
LinkDB
Position
11:complement(25481555..25485973)
AA seq 374 aa
MSLAGDVCVLSGACGFLGEKLVRLLLEEEKLAEIRLLDKNIRPELVQSLEDRCGDTKLSV
FEGDIRDNELLRRACRGATLVFHTASLIDVIGAIDYRELYEVNVKGTQLLLETCIQESVA
SFIYTSSIEVAGPNPRGEPIINGNEDTVYTSSLKFPYSQTKKEAEQLCLNAQGELLSNGG
RLATCVLRPMYIYGEGCRFTLGHMRDGIRNGDVLLRTSSREAKVNPVYVGNVALAHLQAA
RALKEPQKRAVVGGNFYYISDNTPPISYSDFNHAVLSPLGFGIQERPVLPFTVLYLIAFL
VEMLQAVLRPFLRFTLPLNRQLLVMLNTPFSFSYQKAHRDLGYTPRYEWAEARKRTTDWL
ASVLAREREQISLK
NT seq 1125 nt   +upstreamnt  +downstreamnt
atgtctctcgccggagatgtgtgtgtgttatcgggagcttgtggttttcttggggagaag
ctggtcaggctgctgctggaggaggagaagcttgcagaaattcgactgctggacaaaaat
atccgaccggaattagtacagtctctggaagatcgctgcggtgacacaaaacttagtgtg
tttgagggagacatcagagacaatgagctgctgaggcgagcctgtagaggagcaacactc
gtatttcacactgcctctcttatagacgtcattggagccatcgactacagagaactgtac
gaggtcaatgtcaaaggtacccagctacttcttgagacatgcatccaggagagcgtggct
tcattcatatatacaagcagcattgaggttgctggtcccaatcctcgtggtgaacctata
atcaacggcaatgaggacactgtgtacacctcgtccttaaagtttccctacagtcaaact
aaaaaggaagctgagcagctttgcctgaatgcccagggagagctgctttccaacgggggt
cgacttgctacctgtgttctgaggccaatgtacatctacggagaaggctgccgcttcact
ttaggccacatgcgagacggtatccgaaacggcgacgtgttactgcggacttcaagtcgc
gaggctaaagtgaaccctgtgtatgtgggaaatgttgctctagcacatctgcaggctgct
cgagccctgaaagagccacagaagagagctgtggtcggaggaaacttctactacatctca
gacaacacgccccccatcagctattctgacttcaatcacgccgttttgtctccgttaggc
tttggcatacaggagaggcctgtcctacctttcaccgttctctacctcatagccttcctc
gttgaaatgctccaagctgtgctccgccccttcctgcgcttcactctgcccctcaacagg
cagcttctggttatgttgaacacgcccttcagcttctcctatcaaaaagcacacagagat
ttgggatacactcctcgttatgagtgggcagaagcacgcaagcgaactactgattggctg
gcatctgtgttagccagagaaagagaacaaattagcctgaagtga

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