Arvicanthis niloticus (African grass rat): 117721049
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Entry
117721049 CDS
T08817
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
anu
Arvicanthis niloticus (African grass rat)
Pathway
anu00350
Tyrosine metabolism
anu00790
Folate biosynthesis
anu01100
Metabolic pathways
anu04728
Dopaminergic synapse
anu04917
Prolactin signaling pathway
anu05012
Parkinson disease
anu05030
Cocaine addiction
anu05031
Amphetamine addiction
anu05034
Alcoholism
Module
anu_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
anu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
117721049 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
117721049 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
117721049 (Th)
09156 Nervous system
04728 Dopaminergic synapse
117721049 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
117721049 (Th)
09165 Substance dependence
05030 Cocaine addiction
117721049 (Th)
05031 Amphetamine addiction
117721049 (Th)
05034 Alcoholism
117721049 (Th)
Enzymes [BR:
anu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
117721049 (Th)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
117721049
NCBI-ProteinID:
XP_034375666
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Position
1:complement(109374318..109382444)
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AA seq
478 aa
AA seq
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MGPVQLTCYRSPRFIGRRQSLIEDARKEREAAAAAAAAAVASSEPGNPLEAVVFEERDGN
AVLNLLFSLRGTKPSSLSRAVKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSG
DLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVY
RQRRKLIAEIAFQYKQGEPIPHVEYTAEEIATWKEVYATLKGLYATHACREHLEAFQLLE
RYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASS
PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLC
KQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDAAAVQPYQDQTYQPVYFVSESFSD
AKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLAHALSAIS
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atgggcccagtacaactcacctgctataggtccccaaggttcatcggacggcggcagagt
ctcattgaggatgcccgaaaggagcgggaagcggcagcagctgcagcagcggcagcggta
gcctcctcagaacctgggaacccactggaggctgtggtatttgaggagagggatgggaat
gctgttctcaacctgctcttctccctgaggggtacaaaaccctcctcactctctcgggct
gtgaaagtgtttgagacatttgaagccaaaatccaccacttagagacccggcctgcccag
aggccactggcaggaagcccccacctggagtactttgttcgctttgaggtgcccagtgga
gacctggctgccctcctcagttctgtgcgtcgggtgtctgacgatgtgcgcagtgccaga
gaggacaaggttccctggttcccgaggaaagtgtcagaattggacaagtgtcaccacctg
gtcaccaagtttgaccctgacctggacctggaccatccgggcttctctgaccaggtgtat
cgccagcgccggaagctgattgcagagattgccttccagtacaagcagggtgaaccaatt
ccccatgtggagtacacagcggaggaaattgctacctggaaggaggtatacgccacgctg
aagggcctctatgctacccacgcctgccgggagcacctggaggctttccagcttctggaa
cggtactgtggctaccgagaggacagcatcccacagctggaggacgtgtcccgcttcttg
aaggagcgaactggcttccagctgcgacccgtggccggtctactgtctgcccgtgatttt
ctagccagtctggccttccgagtgtttcaatgcacacagtacattcgccatgcctcctca
cctatgcattcacctgagccggactgctgccatgagctgttgggacacgtacccatgttg
gctgaccgcacatttgcccagttctcccaggacattggacttgcatctctgggggcctca
gatgaagaaattgagaaactctccacggtgtactggttcaccgtggagtttgggctgtgt
aaacagaacggggagctgaaggcttatggtgcagggctgctgtcttcctatggagagctc
ctgcactccctgtcagaggagcctgaggtccgggcctttgacccggacgcagcagccgtg
cagccctaccaagaccaaacctaccagccagtgtactttgtgtccgagagcttcagcgat
gccaaggacaagctcaggaactatgcctctcgtattcagcgcccattctccgtgaagttt
gacccgtacacactggccatcgatgtgctggacagtcctcacaccatccggcgctccttg
gagggggtccaggatgaactgcacaccctggcccatgcactgagtgccattagctaa
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