KEGG   Amycolatopsis orientalis: SD37_09330
Entry
SD37_09330        CDS       T06703                                 
Name
(GenBank) beta-ketoacyl synthase
  KO
K05552  minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
aori  Amycolatopsis orientalis
Pathway
aori00253  Tetracycline biosynthesis
aori01056  Biosynthesis of type II polyketide backbone
aori01100  Metabolic pathways
aori01110  Biosynthesis of secondary metabolites
Module
aori_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:aori00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    SD37_09330
   00253 Tetracycline biosynthesis
    SD37_09330
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:aori01004]
    SD37_09330
   01008 Polyketide biosynthesis proteins [BR:aori01008]
    SD37_09330
Enzymes [BR:aori01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     SD37_09330
    2.3.1.260  tetracycline polyketide synthase
     SD37_09330
Lipid biosynthesis proteins [BR:aori01004]
 Polyketide synthase
  Component type
   SD37_09330
Polyketide biosynthesis proteins [BR:aori01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     SD37_09330
    Nonaketide PKS
     SD37_09330
    Decaketide PKS
     SD37_09330
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_C_1
Other DBs
NCBI-ProteinID: ANN15829
UniProt: A0A193BUI0
LinkDB
Position
1935848..1937077
AA seq 409 aa
MSLPTTSRAVVTGLGVTAPTGLGIDEYWAATLAGHSAIDRITRFDPAPYPAQLAGEIRGF
TAEEHLPGRLLPQTDRMTQLSLVSADWAFLDSGLAPADLPEFQAGVITASHSGGFEFGQN
ELKALWSKGSQYVSAYQSFAWFYAVNSGQISIRNNLRGPSSVLVSDQAGGLDAVAQARRQ
IRRGTSLVVCGAVDASICPWSWVAQLTGGRLSLGKDPKNAYLPFDDRAAGHVPGEGGALL
VLEDERHARDRGAPRIYGEIAGHAATMDPPPGSDRPSGLRRAIEQAMADATIEPEDVDVV
FADAAAVRSLDEAEADALVAIFGPGGVPVTAPKATTGRLYSGAASLDLAAAFLSIRDRVV
PPTIGTSLSPRYEIDLVTGTPRAVDVRCALVLARGQSGFNSAVVVRAFD
NT seq 1230 nt   +upstreamnt  +downstreamnt
atgagccttccgaccaccagccgggccgtggtgaccggtctgggtgtgaccgcgccgacc
ggcctggggatcgacgaatactgggcggccactctcgccgggcacagcgccatcgaccgg
atcacccgtttcgacccggctccctacccggctcaactggcgggagagatccgcggcttc
accgcggaagagcatctgcctggccgcctgctgccgcagaccgaccggatgacgcagctg
tcgctcgtcagtgccgattgggcattcctcgattccgggctggcaccggccgacctgccc
gagttccaggcgggagtgatcacggccagccattcaggcgggttcgagttcggccagaac
gaattgaaagcgttatggagcaagggcagccagtatgtcagcgcctatcagtcgttcgcc
tggttctatgcggtcaacagtggccagatctccattcgcaacaacctccgcggaccgagc
agtgtgctggtgagcgaccaagccggcggtctcgacgcggtcgctcaagctcgtagacag
atccggcggggaacgtcactggtcgtctgtggggcggtcgacgcgtcgatctgcccgtgg
agttgggtcgcgcagctgaccggcggcaggctaagccttggcaaggatccgaagaacgcg
tacctgccgttcgacgaccgtgcggccggccatgtgccgggtgagggtggggcgctgttg
gtgctggaggatgagcggcacgcgcgggatcgtggtgcgcctcggatctacggcgagata
gcggggcacgccgccacgatggatccgccgccgggaagtgaccggccgtccggcctgcgc
cgggcgatcgagcaggcgatggcggacgcgaccatcgagccggaagacgtcgatgtggtc
ttcgcggacgcggcggctgtgcgatcgctggacgaggcagaggccgacgcgctggtggcg
atattcggtcccggtggagtcccggtgaccgcgcccaaggcgacaaccggccgcctgtac
tccggtgccgcctcgctcgacctggccgcggcgtttctgagcatccgcgatcgtgtcgtt
ccaccgaccatcggcacctctctgtcgccgcgttatgagatcgatctcgtcaccgggacg
cccagagctgtcgacgtgcggtgcgccctcgtgctcgcccgcggccaaagcggattcaac
tccgccgtggtcgtccgcgccttcgactga

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