KEGG   PATHWAY: baft04156
Entry
baft04156                   Pathway                                
Name
Integrated stress response (ISR) signaling pathway - Borreliella afzelii Tom3107
Class
Cellular Processes; Cell growth and death
Pathway map
baft04156  Integrated stress response (ISR) signaling pathway
baft04156

Organism
Borreliella afzelii Tom3107 [GN:baft]
Gene
P612_01060  [KO:K14230]
P612_01325  [KO:K04043]
P612_02635  dnaK; molecular chaperone DnaK [KO:K04043]
P612_02850  [KO:K04079]
P612_03165  [KO:K14230]
P612_03195  [KO:K14230]
P612_03360  groEL; molecular chaperone GroEL [KO:K04077] [EC:5.6.1.7]
Compound
C00032  Heme
C00035  GDP
C00044  GTP
Reference
  Authors
Lu HJ, Koju N, Sheng R
  Title
Mammalian integrated stress responses in stressed organelles and their functions.
  Journal
Acta Pharmacol Sin 45:1095-1114 (2024)
DOI:10.1038/s41401-023-01225-0
Reference
  Authors
Kalinin A, Zubkova E, Menshikov M
  Title
Integrated Stress Response (ISR) Pathway: Unraveling Its Role in Cellular Senescence.
  Journal
Int J Mol Sci 24:ijms242417423 (2023)
DOI:10.3390/ijms242417423
Reference
  Authors
Kalinin A, Zubkova E, Beloglazova I, Parfyonova Y, Menshikov M
  Title
Integrated Stress Response (ISR) Modulators in Vascular Diseases.
  Journal
Cells 15:cells15010002 (2025)
DOI:10.3390/cells15010002
Reference
  Authors
Jiang W, Hong Y, Wang P, Yang X, Shao K, Li M, Wu D
  Title
Current Knowledge of the Integrated Stress Response in the Development and Management of Acute Myeloid Leukemia: A Novel Target with Encouraging Progress.
  Journal
Drug Des Devel Ther 19:11269-11288 (2025)
DOI:10.2147/DDDT.S573043
Reference
  Authors
Paerhati P, Liu J, Jin Z, Jakos T, Zhu S, Qian L, Zhu J, Yuan Y
  Title
Advancements in Activating Transcription Factor 5 Function in Regulating Cell Stress and Survival.
  Journal
Int J Mol Sci 23:ijms23137129 (2022)
DOI:10.3390/ijms23137129
Reference
  Authors
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, Han Q, He H, Zhou Q
  Title
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
  Journal
Cell Death Dis 13:156 (2022)
DOI:10.1038/s41419-022-04602-5
KO pathway
ko04156   

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