Bison bison bison (American bison): 104985538 Help Entry 104985538         CDS       T08726                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism bbis  Bison bison bison (American bison) Pathway bbis01524   Platinum drug resistance bbis04010   MAPK signaling pathway bbis04115   p53 signaling pathway bbis04148   Efferocytosis bbis04210   Apoptosis bbis04215   Apoptosis - multiple species bbis04623   Cytosolic DNA-sensing pathway bbis04650   Natural killer cell mediated cytotoxicity bbis04657   IL-17 signaling pathway bbis04668   TNF signaling pathway bbis04726   Serotonergic synapse bbis04932   Non-alcoholic fatty liver disease bbis04933   AGE-RAGE signaling pathway in diabetic complications bbis04936   Alcoholic liver disease bbis05010   Alzheimer disease bbis05012   Parkinson disease bbis05014   Amyotrophic lateral sclerosis bbis05016   Huntington disease bbis05020   Prion disease bbis05022   Pathways of neurodegeneration - multiple diseases bbis05132   Salmonella infection bbis05133   Pertussis bbis05134   Legionellosis bbis05145   Toxoplasmosis bbis05146   Amoebiasis bbis05152   Tuberculosis bbis05160   Hepatitis C bbis05161   Hepatitis B bbis05162   Measles bbis05163   Human cytomegalovirus infection bbis05164   Influenza A bbis05165   Human papillomavirus infection bbis05167   Kaposi sarcoma-associated herpesvirus infection bbis05168   Herpes simplex virus 1 infection bbis05169   Epstein-Barr virus infection bbis05170   Human immunodeficiency virus 1 infection bbis05200   Pathways in cancer bbis05203   Viral carcinogenesis bbis05205   Proteoglycans in cancer bbis05206   MicroRNAs in cancer bbis05210   Colorectal cancer bbis05222   Small cell lung cancer bbis05416   Viral myocarditis bbis05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:bbis00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104985538 (CASP3)    04668 TNF signaling pathway     104985538 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     104985538 (CASP3)   09143 Cell growth and death    04210 Apoptosis     104985538 (CASP3)    04215 Apoptosis - multiple species     104985538 (CASP3)    04115 p53 signaling pathway     104985538 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     104985538 (CASP3)    04650 Natural killer cell mediated cytotoxicity     104985538 (CASP3)    04657 IL-17 signaling pathway     104985538 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     104985538 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104985538 (CASP3)    05206 MicroRNAs in cancer     104985538 (CASP3)    05205 Proteoglycans in cancer     104985538 (CASP3)    05203 Viral carcinogenesis     104985538 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     104985538 (CASP3)    05222 Small cell lung cancer     104985538 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     104985538 (CASP3)    05161 Hepatitis B     104985538 (CASP3)    05160 Hepatitis C     104985538 (CASP3)    05164 Influenza A     104985538 (CASP3)    05162 Measles     104985538 (CASP3)    05168 Herpes simplex virus 1 infection     104985538 (CASP3)    05163 Human cytomegalovirus infection     104985538 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     104985538 (CASP3)    05169 Epstein-Barr virus infection     104985538 (CASP3)    05165 Human papillomavirus infection     104985538 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     104985538 (CASP3)    05133 Pertussis     104985538 (CASP3)    05134 Legionellosis     104985538 (CASP3)    05152 Tuberculosis     104985538 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     104985538 (CASP3)    05145 Toxoplasmosis     104985538 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     104985538 (CASP3)    05012 Parkinson disease     104985538 (CASP3)    05014 Amyotrophic lateral sclerosis     104985538 (CASP3)    05016 Huntington disease     104985538 (CASP3)    05020 Prion disease     104985538 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     104985538 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     104985538 (CASP3)    05416 Viral myocarditis     104985538 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     104985538 (CASP3)    04932 Non-alcoholic fatty liver disease     104985538 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     104985538 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     104985538 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:bbis01002]     104985538 (CASP3) Enzymes [BR:bbis01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      104985538 (CASP3) Peptidases and inhibitors [BR:bbis01002]  Cysteine peptidases   Family C14: caspase family    104985538 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  104985538 NCBI-ProteinID:  XP_010834058 Ensembl:  ENSBBBG00000014877 UniProt:  A0A6P3GRB6 LinkDB All DBs Position Unknown AA seq 277 aa AA seqDB search MSMENTENSVDSKSIKTSETKILHGSKSMDSGISLEESYKMDYPEMGLCIIINNKNFHEN TGMACRSGTDVDAANLRETFMNLKYEVRIKNDLTCKEMLELMSNVSKEDHSKRSSFICVL LSHGEEGIIFGTNGPVNLKKLASFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGA EDDMACQKIPVEADFLYAYSTAPGYFSWRNAKNGSWFIQALCEMLNKYAHRLELMHILTR VNRKVAIEYESFSTDSAFHAKKQIPCIMSMLTKELYF NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atgtccatggagaacactgaaaattcagtggattcaaaatccattaaaacttcagagaca aagatcttacatggaagcaaatcaatggactctggaatatccttggaagagagttacaaa atggattatcctgaaatgggtttatgtataataatcaataataagaacttccacgaaaat actggtatggcctgtcgatctggtacagacgtggatgcagcaaacctcagggaaacattc atgaacttgaaatacgaagtcaggattaaaaatgatcttacatgtaaagaaatgttggaa ttaatgagcaacgtttctaaagaagaccatagcaaaaggagcagttttatttgcgtgctt ctaagccatggtgaagaaggaatcatttttggaaccaatggacccgtcaatttgaaaaaa ttagcaagtttcttcagaggggactattgcagaagtctgactggaaaacccaaacttttc attattcaggcctgccgaggcacagaactggactgtggtattgagacagacagtggtgct gaggatgacatggcctgtcagaaaataccagttgaggcagacttcttgtacgcatattct acagcacctggttacttttcctggcgaaatgcaaagaacggatcctggttcatccaggct ctttgtgagatgctgaataagtacgctcacaggctcgagctcatgcacattcttactcgg gttaaccgaaaggtagcaatagaatatgagtccttttctaccgattctgcttttcatgca aagaaacagattccttgtattatgtctatgctcacaaaagaactgtatttctaa

DBGET integrated database retrieval system