Bos indicus (zebu cattle): 109554672
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Entry
109554672 CDS
T04792
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
biu
Bos indicus (zebu cattle)
Pathway
biu00350
Tyrosine metabolism
biu00790
Folate biosynthesis
biu01100
Metabolic pathways
biu04728
Dopaminergic synapse
biu04917
Prolactin signaling pathway
biu05012
Parkinson disease
biu05030
Cocaine addiction
biu05031
Amphetamine addiction
biu05034
Alcoholism
Module
biu_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
biu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
109554672 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
109554672 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
109554672 (TH)
09156 Nervous system
04728 Dopaminergic synapse
109554672 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
109554672 (TH)
09165 Substance dependence
05030 Cocaine addiction
109554672 (TH)
05031 Amphetamine addiction
109554672 (TH)
05034 Alcoholism
109554672 (TH)
Enzymes [BR:
biu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
109554672 (TH)
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GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
109554672
NCBI-ProteinID:
XP_019810904
UniProt:
A0A6P5BKV8
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Position
29:51348912..51356926
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AA seq
491 aa
AA seq
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MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAASSSE
SAEAGSLVERDGKAVLTLLFALRPTKPPALTRAIKVFETFEAHLHHLETRPAQPLRAGSP
PLECFVRCEVPGPVVPALLSALRRVAEDVRAAGESKVLWFPRKVSELDKCHHLVTKFDPD
LDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYSTLRGLYPTH
ACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFR
VFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGVSDEEIEKL
STLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQT
YQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRALDGVQDEM
QALAHALNAIS
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
atgcctacccccaacgccgcctcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggctgaggccatcatgtccccacgcttcgtcgggaggcggcagagc
ctcatccaggacgcacgcaaggagcgggagaaggcggaggccgcggcctcatcctcggag
tccgcggaggcgggcagcctggtggagagggacgggaaggcggtgctgaccctgctgttc
gccctgcggcccaccaagccccctgcgctgacccgggctatcaaggtgtttgagacattc
gaagcccacctccaccacctggagacccgaccggcccagccactgcgggcggggagcccg
cccctggagtgcttcgtgcgctgtgaggtgcccggcccagtggtgcccgccctgctgagc
gccctgcgccgcgtggcagaagatgtgcgtgccgctggggagagcaaagtcctctggttc
ccaaggaaagtgtccgagctggacaagtgtcaccacctcgtcaccaagtttgaccctgac
ctggacttggatcatcccggcttctccgaccaggcgtaccgccagcgcaggaagctgatc
gccgagatcgccttccagtacaagcaaggcgaccccattccccacgtggagtacacagcc
gaggagacagccacctggaaggaggtctactccacgctgcggggcctgtaccccacccac
gcctgccgcgagcacctggaggccttcgagctgctggagcgcttctgcgggtaccgygag
gaccgaatcccgcagctggaggacgtctcacgcttcctgaaggagaggaccggcttccag
ctgcggcccgtggccggcctgctgtccgcgcgggacttcctggccagcctggccttccgc
gtgttccagtgcacccagtacatccgccacgcctcctcgcccatgcactccccggagccg
gactgctgccacgagctgctggggcacgtgcccatgctcgccgaccggaccttcgcgcag
ttttcccaggacatcgggctcgcatccttgggagtgtcggatgaggaaattgagaagctg
tccacgctgtactggttcaccgtggagttcgggctatgcaaacagaatggagaggtgaag
gcctacggcgcggggctgctgtcctcctacggggagctcctgcactccctttccgaggag
cccgagatccgggccttcgaccctgatgcagcggccgtgcagccctatcaggaccagacc
taccagcccgtctacttcgtgtctgagagcttcagcgatgccaaggacaagctcaggagc
tacgcctcccgcatccagcgccccttctctgtgaagtttgacccgtacacactggccatc
gacgtgctggacagtccccacgccatccggcgcgccctggacggcgtccaggacgagatg
caggccctggcccatgctctgaacgccatcagctag
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