Balaenoptera musculus (blue whale): 118899690
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Entry
118899690 CDS
T09887
Symbol
TH
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
bmus
Balaenoptera musculus (blue whale)
Pathway
bmus00350
Tyrosine metabolism
bmus00790
Folate biosynthesis
bmus01100
Metabolic pathways
bmus04728
Dopaminergic synapse
bmus04917
Prolactin signaling pathway
bmus05012
Parkinson disease
bmus05030
Cocaine addiction
bmus05031
Amphetamine addiction
bmus05034
Alcoholism
Module
bmus_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
bmus00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
118899690 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118899690 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
118899690 (TH)
09156 Nervous system
04728 Dopaminergic synapse
118899690 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
118899690 (TH)
09165 Substance dependence
05030 Cocaine addiction
118899690 (TH)
05031 Amphetamine addiction
118899690 (TH)
05034 Alcoholism
118899690 (TH)
Enzymes [BR:
bmus01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
118899690 (TH)
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GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
118899690
NCBI-ProteinID:
XP_036717439
UniProt:
A0A8B8Y6G2
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Position
8:108687918..108694977
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AA seq
497 aa
AA seq
DB search
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAAAAAE
PGEALEERDGKAVVNLLFTLRATKPPVLSRAVKVFETFEAQIHHLETRPAQKPRAGGSHL
EYFLRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLD
LDHPGFSDQVYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETAPGETPXWNEVYTTLRGLY
ATHACREHLEAFELLEHFCGYREXSIPQLEDVSRFLKGCDARTGFQLRPVAGLLSARDFL
ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD
EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEGPEIRAFDPDAAAVQ
PYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRALD
GVRDELHTLTHALSAIS
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccaacgccgcctcgccgcaggccaagggcttccgcagggctgtctccgag
ctggacgccaagcaggccgaggccatcatgtccccgcgcttcgtcgggagacggcagagc
ctcatccaggacgcccgcaaggagcgagagaaggcggaggccgcagccgcagccgcggag
cctggggaggccctggaggagagggacgggaaggccgtggtgaacctcctcttcaccctg
cgggccaccaagccccccgtgctgtcgcgggccgtgaaggtgtttgagacatttgaagcc
caaatccaccacctggagacccggcccgcccagaaaccgcgggcagggggctcgcacctg
gagtatttcctgcgctgtgaggtacccagcgccgccctgcccaccctgctcagctccctt
cgccgtgtggccgaagacgtgcggggcgccggggagaacaaggtcctctggttcccaagg
aaagtttctgagctggacaagtgtcaccacctggtcaccaagtttgaccctgacctggac
ttggaccatccgggattctcggaccaggtgtaccgccagcgcaggaagctgattgctgag
atcgccttccagtacaagcaaggcgaccctattccccacgtggagtacacggccgaggag
actgcacctggtgagaccccgtgatggaatgaggtctacaccacgctgcggggcctctac
gccacccacgcgtgccgggaacacctggaggctttcgagctgctggagcacttctgcggg
taccgggagngaagcatcccccagctggaggacgtctcccgcttcctgaaggggtgcgac
gctcggaccggcttccagctgcggcccgtggccggcctgctgtctgcccgggacttcctg
gccagcctggccttccgcgtgttccagtgcacgcagtatatccgccacgcctcctcaccc
atgcactcccccgagccggactgctgccacgagctgctggggcacgtgcccatgctggcc
gaccggaccttcgcccagttctcccaggacatcggcctcgcatccctgggggcatcggac
gaagaaattgagaagctgtccacgctgtactggttcaccgtggagtttgggctgtgcaag
cagaacggcgaggtgaaggcctacggagcggggctgctgtcctcctatggggagctcctg
cactccctgtctgagggccccgagatccgggccttcgaccccgacgcagcggctgtgcag
ccctaccaggaccagacttatcagcctgtctacttcgtgtctgagagtttcagcgatgcc
aaggacaagctcaggagctatgcctcccgcatccaacgccccttctccgtgaagttcgac
ccatacacgctggccatcgatgtgctggacagtccccacgccatccgacgcgccctggat
ggtgtccgggacgagctgcacaccctcacccacgccctgagtgccatcagctag
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