KEGG   Balaenoptera musculus (blue whale): 118903580
Entry
118903580         CDS       T09887                                 
Name
(RefSeq) LOW QUALITY PROTEIN: steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
bmus  Balaenoptera musculus (blue whale)
Pathway
bmus00140  Steroid hormone biosynthesis
bmus01100  Metabolic pathways
bmus04925  Aldosterone synthesis and secretion
bmus04927  Cortisol synthesis and secretion
bmus04934  Cushing syndrome
Module
bmus_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:bmus00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    118903580
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    118903580
   04927 Cortisol synthesis and secretion
    118903580
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118903580
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:bmus00199]
    118903580
Enzymes [BR:bmus01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     118903580
Cytochrome P450 [BR:bmus00199]
 Cytochrome P450, animal type
  CYP21 family
   118903580
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 118903580
NCBI-ProteinID: XP_036724663
UniProt: A0A8B8YQC2
LinkDB
Position
11:23922808..23925405
AA seq 497 aa
MVPAGLLLLLLLPLLVGTRLLWGQWKLRSLHLPPLVPGFLHLLQPNLPMYLLSLAQKLGP
IYRLRLGLQDVVVLNSKRTIEEALIRKWVDFAGRPQIPSYRLVSQHCQDISVGDYSLLWK
AHKKLTRSALLLGVRGSMEPRVEQLTQEFCERMKAQAGAPVTIQKEFSLLTCSIICYLTF
GDKEDTLVHAFHDCVQDLMKTWDHWSIQILDMVPFLRFLPNPGLWRLKQAMENRDHIVEK
QLRQHKESMVAGQWRDMTDYMLQGMGKQRLEEGPGQLLEGHVHMSVVDLFIGGTETTANT
LSWAVAFLLHHPEIQRRLQEELDRELGPGASGSRVPYKDRARLPLLNATIAEVLRLRPIV
PLALPHRATRASSIFGYDIPEGMVVIPNLQGAHLDETVWERPHEFRPDRFLDPGANPQRA
GLGCGARVCLGEPLARLELFVVLGQLLQAFTLLSPAGALPSLQPHPYCGVNLKIQPFQVR
LQPRGAEAGAWASASDQ
NT seq 1494 nt   +upstreamnt  +downstreamnt
atggtacccgcggggctgctactgctgctgctgctgcccctgctagtcggcacgcgcctg
ctgtggggccagtggaagctcaggagcctccacctcccacctcttgtccccggcttcctg
cacctgctgcagcccaacctccccatgtatctgcttagcctggctcagaaactcgggccc
atctacaggctccgcctcggcctgcaagatgtggtggtgctgaactccaagaggaccatt
gaggaggccctgatcaggaagtgggtggactttgccggcagaccccagataccgtcctac
cggctggtgtctcagcactgccaggacatctcagtaggggactactccctgctctggaag
gcccacaagaaactcacgcgctcggccctgctgctgggcgtccgcggctccatggagccc
cgggtggagcagctgacccaggagttctgtgagcgcatgaaagcccaggctggtgccccc
gtgaccatccagaaggaattctctctcctcacctgcagcatcatctgttacctcaccttt
ggagacaaggaggacaccttagtacacgcctttcacgactgtgtccaggacttgatgaaa
acctgggaccactggtccatccaaattttggacatggttccctttctcaggttcctcccc
aaccccgggctctggaggctgaagcaggccatggagaacagggaccacattgtagagaag
cagctgaggcagcacaaggagagcatggtggccggccagtggagggacatgacagactac
atgctccaggggatggggaagcaaagattggaagagggccccggacagctccttgaaggg
cacgtgcatatgtctgtggtggaccttttcatcggtggcactgagaccacggcaaacacc
ctttcctgggctgtggcgttcctgcttcaccaccctgagattcagcggcgactgcaggag
gagttggatcgcgagctgggccccggagcctcgggctcccgagtcccatacaaggaccgc
gctcggctgcccttgctcaacgccaccatcgctgaggtgctgcgcctgcggcccatcgtg
cccctggccttgccgcaccgcgccacgcgggcgagcagcatcttcggctacgacatcccc
gagggcatggttgtcatccccaacctccaaggtgcccacctggacgagactgtgtgggag
cggccgcacgagttccggcccgaccgcttcctggacccgggcgcgaacccccagcgcgct
ggccttggctgcggggcgcgcgtgtgcctgggcgagccgctggcgcgcctcgagctcttc
gtggtgctggggcaactgctgcaggccttcacgctgctgtcacccgcgggcgccctgccc
tcgctgcagccccatccctactgcggcgtcaacctcaagattcagcctttccaggtgcgg
ctgcagccccggggagcggaggccggggcgtgggcgagcgccagtgaccagtga

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