KEGG   PATHWAY: bpm00740
Entry
bpm00740                    Pathway                                
Name
Riboflavin metabolism - Burkholderia pseudomallei 1710b
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
bpm00740  Riboflavin metabolism
bpm00740

Other DBs
GO: 0006771
Organism
Burkholderia pseudomallei 1710b [GN:bpm]
Gene
BURPS1710b_A0081  toxB; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
BURPS1710b_A2481  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
BURPS1710b_3102  ribBA; bifunctional riboflavin biosynthesis protein RibBA [KO:K14652] [EC:4.1.99.12 3.5.4.25]
BURPS1710b_A0085  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
BURPS1710b_3100  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
BURPS1710b_0895  ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
BURPS1710b_3103  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
BURPS1710b_3101  ribE; riboflavin synthase, alpha subunit [KO:K00793] [EC:2.5.1.9]
BURPS1710b_1124  ribF; riboflavin biosynthesis protein RibF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
BURPS1710b_2215  ntaB; nitrilotriacetate monooxygenase [KO:K23462] [EC:1.5.1.36]
BURPS1710b_A0451  NADPH-dependent FMN reductase family protein [KO:K00299] [EC:1.5.1.38]
BURPS1710b_3222  nitroreductase family protein [KO:K04719] [EC:1.13.11.79]
BURPS1710b_A0097  putative hydroxyethylthioazole kinase [KO:K00878] [EC:2.7.1.50]
BURPS1710b_1451  pyrophosphatase, MutT/nudix family [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BURPS1710b_3606  ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
bpm00030  Pentose phosphate pathway
bpm00040  Pentose and glucuronate interconversions
bpm00230  Purine metabolism
bpm00860  Porphyrin metabolism
bpm00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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