Bos taurus (cow): 517541
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Entry
517541 CDS
T01008
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
bta
Bos taurus (cow)
Pathway
bta04148
Efferocytosis
bta04330
Notch signaling pathway
bta04668
TNF signaling pathway
bta05010
Alzheimer disease
bta05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
bta00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
517541 (ADAM17)
04668 TNF signaling pathway
517541 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
517541 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
517541 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
517541 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
bta01002
]
517541 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
bta04090
]
517541 (ADAM17)
Enzymes [BR:
bta01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
517541 (ADAM17)
Peptidases and inhibitors [BR:
bta01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
517541 (ADAM17)
CD molecules [BR:
bta04090
]
Proteins
517541 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
517541
NCBI-ProteinID:
XP_002691532
BGD-bta:
BT26034
Ensembl:
ENSBTAG00000001141
VGNC:
25607
UniProt:
A0AAA9SM15
LinkDB
All DBs
Position
11:87917595..87961887
Genome browser
AA seq
825 aa
AA seq
DB search
MRHRVLLLTSLVHLVLAPRPPDERESPRRFEKLDSLLSDYDILSLSNIQQHSVRKRELQA
STHLETLLTFSALKRHFKLYLTSSTERFSKNFKVVVVDGKDEREYPVKWQDFFSGHVVGE
PDSRVLAHIGDDDITIRINTDGAEYNIEPLWRLINDTKDKRMLVYKSEDIKNVSRLQSPK
VCGYIKANNEELLPKGLVDSEPPDELVHRVKRRADPNPLKNTCKLLVVADHRFYKYMGRG
EESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQVVKPGERHFNMAK
SYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHG
GVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAE
CAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKSQECFQERSNKVCGNSR
VDEGEECDPGIMYLNNDTCCNSDCTLRPGVQCSDRNSPCCKNCQFETAQKKCQEAINATC
KGVSYCTGNSSECPPPGNAADDTVCLDLGKCKDGKCVPFCEREQRLESCACNETDNSCKV
CCRDPSGRCVPYVNAEQKNLFLRKGKPCTVGFCDTNGKCEKRVQDVIERFWEFIDKLSIN
TFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQFESLSLFHPSNVEMLSSMDSA
SVRIIKPFPAPQTPGRLQTTPVMPPAPSAPLAPKLDHQRMDTIQEDPSTDSHADEDGFEK
DPFPNSSAAAKSFEDLTDHPVTRSEKASSFKLQRQNRVDSKETEC
NT seq
2478 nt
NT seq
+upstream
nt +downstream
nt
atgaggcaccgtgtcctcttgctcaccagcttggttcatctggtgctggcgccgcgacct
cctgacgagcgggaatccccgcggcgattcgaaaagcttgattctttgctctcagactac
gatatcctctccttatccaatatccagcagcactctgtgagaaaaagggagctgcaggcc
tcgacacacttagaaacactactgactttttcagccttgaaaaggcattttaaattatac
ctgacatcaagtactgaacgcttttccaaaaatttcaaagtcgtggtggtagatgggaaa
gatgaaagggagtaccccgtcaaatggcaggacttctttagcggacatgtggttggtgag
cctgactctagggttctggcacacattggagatgatgatattacaataagaatcaacaca
gatggggcagaatataatatagagccgctttggagactaattaatgatactaaagacaaa
agaatgttagtttataaatctgaagatatcaagaatgtttcacgtttgcagtctccaaaa
gtgtgtggttatataaaggcgaataatgaagagttgcttccaaaaggcctggtagacagc
gagccacctgatgagcttgttcatcgagtgaagagacgagctgaccctaatcccttgaag
aacacgtgtaaattattggtggtagcagatcatcgcttttacaaatacatgggcagaggg
gaagagagtacaactaccaactacttgatagagctaattgacagagttgatgacatctat
cgaaacacttcatgggacaatgcaggttttaaaggttatggaatacagatagaacagatt
cgcattctcaagtctccacaagtggtaaaacctggtgaaaggcacttcaatatggcaaaa
agttacccaaatgaagaaaaagatgcttgggatgtgaagatgttgctagagcaatttagt
tttgatattgctgaagaagcatctaaagtctgcctagcacatcttttcacgtaccaagat
tttgatatgggaacccttggcttagcttatgttggttctcccagagcgaacagtcacgga
ggtgtttgtccaaaggcttattacagtccaattggaaagaaaaatatctatttgaatagt
ggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgacctcgtt
acaactcacgaattggggcacaactttggagcagagcacgacccagatggtctggcggaa
tgtgccccaaatgaggaccagggagggaagtatgtcatgtaccccatagctgtgagcggc
gaccacgagaacaataagatgttttcaaactgcagtaaacagtccatctataagaccatt
gaaagcaagtcccaggagtgtttccaggaacgcagcaacaaagtgtgcgggaactccagg
gtggacgagggcgaggagtgcgaccccggcatcatgtacctcaacaacgacacttgctgc
aacagcgactgcacgctgaggccgggtgtgcagtgcagtgacaggaacagtccttgctgt
aaaaactgtcagttcgagacggcccagaagaagtgccaagaggccattaacgctacttgc
aaaggcgtgtcttattgtacaggtaacagcagcgagtgcccacctcccggaaacgcagcc
gatgacaccgtgtgcctggatctcggcaagtgtaaggacggcaagtgcgtgcccttctgc
gaacgcgagcagaggctggagtcctgtgcgtgtaatgaaaccgacaactcgtgcaaggtg
tgctgcagggacccctcgggccgctgcgtgccttacgtcaacgccgaacagaagaacttg
tttttgaggaagggcaagccctgtacagtaggcttctgtgatacgaatggcaaatgtgaa
aagcgagtgcaggatgtcatcgagcgtttctgggagttcattgacaagctgagcatcaat
actttcgggaagtttctagcagacaacatcgtcggttccgtcctggttttctccttgata
ttctggattcctttcagcattctggtccattgtgtggataagaaactggataagcagttt
gagtctctgtctctgttccaccccagtaacgtcgagatgctgagcagcatggactcggcc
tcggtgcgcatcatcaagccctttcctgcgccccagacccctggtcgcctgcagaccacc
cccgtgatgccccccgcgccctctgcgcccctggccccgaagctggaccaccagcggatg
gacaccatccaggaagacccgagcacggactcacatgccgatgaggatggctttgagaag
gatcccttcccaaatagcagtgcagctgccaagtcattcgaggaccttacagaccatcca
gtcaccagaagtgaaaaggcctcgtccttcaagctgcagcgtcagaaccgcgtggacagc
aaggagaccgagtgctag
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