Colobus angolensis palliatus (Angola colobus): 105503232
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Entry
105503232 CDS
T08744
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
cang
Colobus angolensis palliatus (Angola colobus)
Pathway
cang00350
Tyrosine metabolism
cang00790
Folate biosynthesis
cang01100
Metabolic pathways
cang04728
Dopaminergic synapse
cang04917
Prolactin signaling pathway
cang05012
Parkinson disease
cang05030
Cocaine addiction
cang05031
Amphetamine addiction
cang05034
Alcoholism
Module
cang_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
cang00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
105503232 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105503232 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
105503232 (TH)
09156 Nervous system
04728 Dopaminergic synapse
105503232 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105503232 (TH)
09165 Substance dependence
05030 Cocaine addiction
105503232 (TH)
05031 Amphetamine addiction
105503232 (TH)
05034 Alcoholism
105503232 (TH)
Enzymes [BR:
cang01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
105503232 (TH)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
105503232
NCBI-ProteinID:
XP_011785471
Ensembl:
ENSCANG00000034710
UniProt:
A0A2K5J0X2
LinkDB
All DBs
Position
Unknown
AA seq
529 aa
AA seq
DB search
MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQVGGPGPSLTGSLWPGTAALAASYTPA
PRSPRFIGRRQSLIEDARKEREAAVAAAAAAAPSEPGDPLEAVAFEEKEGKAVLNLLFSP
RATKPSALSRAVKVFETFEAKIHHLETRPAQRLRAGGPHLEYFVRLEVPRGDLAALLSGV
RQVSEDVRSPAEPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAE
IAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDN
IPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDC
CHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAY
GAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFGDAKDKLRSYA
ARIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccgacgccaccacaccacaggccaagggcttccgcagggctgtgtctgag
ctggatgccaagcaggcagaggccatcatggtaagagggcaggtagggggacccgggccc
agcctcacgggctctctgtggcctggaactgcagccctagctgcatcctacacccccgcc
ccgaggtccccgcggttcattgggcgacggcagagcctcatcgaggatgcccgcaaggag
cgggaggcggcggtggcagcagcagctgctgcagccccctcggagcccggggaccccctg
gaggccgtggcctttgaggaaaaggaggggaaggccgtgctaaacctgctgttctccccg
agggccaccaagccctcagcgctgtcccgagctgtgaaggtgtttgagacgtttgaagcc
aaaatccaccacctagagacccggcccgcccagaggctgcgagccgggggcccccacctg
gagtactttgtgcgcctcgaggtgccccgaggggacctggccgccctgctcagtggtgtg
cgccaggtgtcggaggacgtgcgcagccccgcggagcccaaggtcccctggttcccaaga
aaagtgtcagagctggacaagtgtcatcacctggtcaccaagtttgaccctgacctggac
ttggaccacccgggcttctcggaccaagtgtaccgccagcgcaggaagctgattgctgag
atcgccttccagtacaggcacggcgacccgattccccgtgtggagtacaccgccgaggag
attgccacctggaaggaggtctacaccaccctgaaaggcctctacgccacgcacgcctgc
ggggagcacctggaggcctttgccctgctggagcgcttcagcggctaccgggaggacaac
attccccagctggaggatgtctcccgcttcctgaaggagcgcacgggcttccagctgcgg
cctgtggctggcctgctgtccgcccgggacttcctggccagcctggccttccgcgtgttc
cagtgcacccagtatatccggcacgcgtcctcgcccatgcactcccctgagccggactgc
tgccacgagctgctggggcacgtgcccatgctggccgaccgcaccttcgcgcagttctcc
caggacatcggcctggcatccctgggggcctcggatgaggaaattgagaagctgtccacg
ctgtactggttcaccgtggagtttgggctgtgcaaacagaacggggaggtgaaggcctat
ggcgcggggctgctgtcctcctatggggagctcctgcactgcctgtctgaggagcccgag
attcgagccttcgaccctgaagcagcagccgtgcagccctaccaagaccagacataccag
tcagtctacttcgtgtctgagagcttcggcgatgccaaggataagctcaggagctatgcc
gcacgcatccagcgccccttctccgtgaagttcgacccgtataccctggccatcgacgtg
ctggacagcccccaggccgtgcggcgctccctggagggtgtgcaggatgagctggacacc
ctggcccatgcgctcagtgccattggctag
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