KEGG   Citrobacter freundii CFNIH1: CFNIH1_06135
Entry
CFNIH1_06135      CDS       T03077                                 
Name
(GenBank) dihydrofolate reductase
  KO
K19644  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
cfd  Citrobacter freundii CFNIH1
Pathway
cfd00670  One carbon pool by folate
cfd00790  Folate biosynthesis
cfd01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:cfd00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    CFNIH1_06135
   00670 One carbon pool by folate
    CFNIH1_06135
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:cfd01504]
    CFNIH1_06135
Enzymes [BR:cfd01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     CFNIH1_06135
Antimicrobial resistance genes [BR:cfd01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    CFNIH1_06135
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: AHY11107
LinkDB
Position
1262572..1263141
AA seq 189 aa
MSHPQLELIVAVDSKLGFGKGGKIPWKCKEDMARFTRISKEIRVCVMGKHTYTDMRDMQL
EKDGAEERIKEKGILPERESFVISSTLKQEDVIGATVVPDLRAVINLYENTDQRIAVIGG
EKLYIQALSSATKLHMTIIPREFDCDRFIPVDPIQNNFHIDSSASETVEATVDETQERIH
FATYVRNNQ
NT seq 570 nt   +upstreamnt  +downstreamnt
atgagtcacccacaacttgagctaatagtcgctgtggattctaagttgggattcgggaaa
ggcggcaagattccatggaaatgcaaagaagacatggcgcgatttacgcggatttctaaa
gagatccgcgtgtgcgttatggggaaacacacgtatactgacatgcgtgacatgcagtta
gaaaaggatggcgccgaggagcgaatcaaggagaaaggaattctccccgaacgcgaatcg
ttcgtgatctcctcgacgttaaaacaagaagatgtcataggcgctactgtcgttcctgat
cttcgtgctgtgatcaacctgtatgagaataccgatcaacgcattgctgtcattggtggg
gagaagttgtacattcaagctctttcatcagcaacgaaactgcacatgaccataattcca
agagagttcgactgtgatcgatttattcctgttgatccgatccagaacaattttcacatt
gattccagtgccagcgagactgtggaggcaaccgttgatgagactcaagagcgcattcac
tttgctacttacgtgcgtaacaatcagtaa

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