KEGG   Capra hircus (goat): 102174710
Entry
102174710         CDS       T02910                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
chx  Capra hircus (goat)
Pathway
chx00140  Steroid hormone biosynthesis
chx01100  Metabolic pathways
chx04925  Aldosterone synthesis and secretion
chx04927  Cortisol synthesis and secretion
chx04934  Cushing syndrome
Module
chx_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:chx00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    102174710
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    102174710
   04927 Cortisol synthesis and secretion
    102174710
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102174710
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:chx00199]
    102174710
Enzymes [BR:chx01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     102174710
Cytochrome P450 [BR:chx00199]
 Cytochrome P450, animal type
  CYP21 family
   102174710
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 102174710
NCBI-ProteinID: XP_017894409
UniProt: A0A452E470
LinkDB
Position
23:22623800..22627599
AA seq 497 aa
MVLAGLLLLLLTLLAGAHLLWGRWKLRNLHLPPLVPGFLHLLQPNLPIHLLSLTQKLGPV
YRLRLGLQEVVVLNSKRTIEEAMIRKWVDFAGRPQIPSYKLVSQRCQDISLGDYSLLWKA
HKKLTRSALLLGTRSSMEPWVEQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICFLTFG
DKEDTLVHAFHDCVQDLMKTWDHWSIQILDMVPFLRLFPNPGLWRLKKAIENRDHMVEKQ
LRRHKESMMAGQWRDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTL
SWAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVP
LALPHRTIRPSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANTSALA
FGCGARVCLGESLARLELFVVLLRLLQAFTLLPPPGGALPSLQPDPYCGVNLKVQPFQVR
LQPRGVEAGACESASAQ
NT seq 1494 nt   +upstreamnt  +downstreamnt
atggtcctcgcagggctgctgctgctgctgctcaccctgctagccggcgctcacctgctg
tggggccggtggaagctcagaaacctccacctcccacctttggtccccggcttcctgcac
ctgctgcagcccaacctccccatccatctgctgagcctgactcagaaactcgggcctgtc
tacaggcttcgccttgggctgcaagaggtggtggtgctaaactccaagaggaccatcgag
gaggctatgatcaggaagtgggtggactttgccggcagaccccagataccatcctacaag
ctggtgtctcagcgctgccaggacatctctctgggggactactctctgctctggaaggcc
cacaagaaactcacccgctcagccttgctgctgggcacccgcagctccatggaaccctgg
gtggagcagctgacccaggagttttgtgagcgcatgagagtccaggccggtgcccccgtg
accatccagaaggaattctctctcctcacttgcagcatcatctgtttcctcacttttgga
gacaaggaggacaccttagtacatgcctttcacgactgtgttcaggacttgatgaagacc
tgggaccactggtccatccagattttggacatggttccttttctcaggctcttccccaac
cctgggctctggaggctgaagaaggccatagagaacagggaccacatggtggagaagcag
ctgaggcgccacaaggagagcatgatggccggccagtggagggatatgacggactacatg
ctccagggggtagggaggcaaagagtagaagagggcccgggacagctcctggaaggacac
gtgcacatgtctgtggtggaccttttcatcgggggcactgaaaccacggccagcaccctc
tcctgggcggtggccttcctacttcaccaccccgagattcagcgccgccttcaggaggag
ttggatcgcgagctgggccccggagcctcgtgctcccgagtcacttacaaggaccgtgct
cggcttcctctgctcaacgccaccatcgcggaggtgctgcgcctgcggccggtcgtgccc
ctggccttgcctcaccgcaccattcggcctagcagcatcttcggctacgacatccctgag
ggcatggtcgttatccccaacctccaaggtgcccacctggatgagaccgtttgggagcag
ccgcacgagttccggccggaccgcttcctggagccgggcgcgaacaccagcgcgctggcg
tttggctgcggggcgcgcgtgtgcctgggcgagtcgctggcgcgcctggagctcttcgtg
gtgctcctgcgactgctgcaggccttcaccctgctgccgccgcccgggggcgccctgccg
tcgctgcagccagatccctactgcggcgtcaacctcaaggtccagcctttccaggtgcgg
ctgcagccccggggggtggaggccggggcctgtgagagcgccagtgcccagtga

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