Capra hircus (goat): 102179849
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Entry
102179849 CDS
T02910
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
chx
Capra hircus (goat)
Pathway
chx00350
Tyrosine metabolism
chx00790
Folate biosynthesis
chx01100
Metabolic pathways
chx04728
Dopaminergic synapse
chx04917
Prolactin signaling pathway
chx05012
Parkinson disease
chx05030
Cocaine addiction
chx05031
Amphetamine addiction
chx05034
Alcoholism
Module
chx_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
chx00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
102179849 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102179849 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
102179849 (TH)
09156 Nervous system
04728 Dopaminergic synapse
102179849 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
102179849 (TH)
09165 Substance dependence
05030 Cocaine addiction
102179849 (TH)
05031 Amphetamine addiction
102179849 (TH)
05034 Alcoholism
102179849 (TH)
Enzymes [BR:
chx01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
102179849 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
102179849
NCBI-ProteinID:
XP_017899069
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Position
29:50402134..50409520
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AA seq
867 aa
AA seq
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MALPPSPSSTLEDRPCWNVLGPAGRAWGSGHSGLAWGQKMLLPRASNRNRPQDPAGKCGG
VKIFRKSKLPPDSCGLSLRIWTDDHQRSRFCVPDTLGCPQHHLPVKPPVTRLGWAEGPGC
TPPCRARPRSPDDSEAGRPPARGPATVDAIRFNGIEPFLGGSVLRAHPASLRRQQREGDV
KEVEVGDLGGSDVSPAYKGRRAEGCGDRARTSPAPCPPPTPPRRRPRASAGPSLSWTPSR
PRPSWGPREVPPTTEAPDSVHTLPEVGLGEGSPRPGCVPRPEGARTFLELQLQVVSPEGL
LCSGVDEADTLTPGARGLRDRWRVRCCQAGLEVGPRGGSSQIPGCHVLWPRGSPGQLLTH
RLPSPDLVRWAQRPPSPPAPGGAVLEPGPGLQAGRGRGQLARLSPQSPRFVGRRQSLIQD
ARKEREKAEAAASSSESAETGSLVERDGKAVLTLLFALRPTKPPALTRAIKVFETFEAHL
QHLETRPAHPPRAGSPPLECFVRCEVPGPVVPALLSSLRRVAEDVRAAGESKVLWFPRKV
SELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETA
TWKEVYSTLRGLYPTHACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPV
AGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQD
IGLASLGVSDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIR
AFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLD
SPRAIRRALDGVQDELQALAHALNAIS
NT seq
2604 nt
NT seq
+upstream
nt +downstream
nt
atggccctgcctccctcaccttcctccacactggaggacaggccctgctggaatgttctg
ggccctgctgggcgtgcttgggggtccgggcacagcggtctggcgtgggggcagaaaatg
ctcctgccgagggcatcgaacagaaacagacctcaggaccccgctgggaaatgtggtggg
gtgaagatcttccggaaaagcaaattgcctccagacagctgtggtctgagcctgcgtatc
tggaccgatgaccaccagaggtcacggttctgtgtgccggacaccctggggtgtccgcaa
caccacctccctgtgaagccgcccgtcacccgcttggggtgggctgaggggcccggctgc
accccgccctgcagagcacgcccccggagcccagatgattcagaggcgggcaggccaccc
gcccgggggcctgcgacagtggatgcaattagatttaatgggatagagccctttctcggc
ggctccgtgctccgcgcccaccccgcctccctcaggcggcagcagcgggagggagatgtg
aaggaggtggaggtgggggacctggggggctctgacgtcagcccagcctataaaggccgc
cgggcagagggctgtggagacagagcccggacctcgccggcaccatgcccacccccaacg
ccgcctcgccgcaggccaagggcttccgccgggccgtctctgagctggacgccaagcagg
ccgaggccatcatggggtcccagggaggtgccccccaccacggaggcccctgactctgtc
cataccctgcctgaggtcggcctgggggagggctcccccaggcccggctgtgttccgaga
cccgagggtgccaggaccttcttagaacttcagctccaggtggtgagcccagaggggctt
ctgtgttcaggggtggacgaggcagacacactgaccccaggggctcgtggtctcagggac
agatggcgggtaaggtgctgtcaggccggactagaggtggggccacgaggagggtcatcc
cagatccccggatgccatgtcctctggccccggggcagcccgggacagctcctgacccac
cgcctcccatcccctgacctggtcaggtgggcgcagaggccgccctcgcccccggcccca
ggcggggcagtgctggagccgggcccggggctgcaggcaggccgagggcgggggcagctg
gcacgcctctccccacagtccccgcgcttcgttgggaggcggcagagcctcatccaggac
gcacgcaaggagcgggagaaggcagaggctgcggcctcatcctcggagtctgcagagacg
ggcagcctggtggagagggatgggaaggcggtgctgacgctgctgtttgccctgcggccc
accaagccccccgcgctgacccgggccatcaaggtgtttgagacattcgaagcccacctc
cagcacctggagacccggccggcccacccgccgcgggcgggtagcccgcccctggagtgc
tttgtacgctgtgaggtgcctggcccggtggtacccgccctgctgagctccctgcgccgc
gtggcggaagacgtgcgtgctgccggggagagcaaggtcctctggttcccgaggaaagtg
tccgagctggacaagtgccaccacctcgtcaccaagtttgaccctgacctggacttggat
cacccgggcttctccgaccaggcgtatcgccagcgcaggaagctgatcgccgagatcgcc
ttccagtacaagcaaggcgaccccattccccacgtggagtacacggccgaggagaccgcc
acctggaaggaggtctactccacgctgcggggcctgtaccccacccacgcctgccgcgag
cacctggaggccttcgagctgctggagcgcttctgcgggtaccgcgaggaccgaatcccg
cagctggaggacgtctcccgcttcctgaaggagcggaccggcttccagctgcggcccgtg
gcaggcctgctgtccgcgcgggacttcctggccagcctggccttccgagtgttccagtgc
acccagtacatccgccacgcctcctcgcccatgcactcccccgagccggactgctgccac
gagctgctggggcacgtgcccatgctcgccgaccggaccttcgcccagttctcccaggac
atcgggctcgcatccttgggagtgtcggatgaggaaattgagaagctgtccacgctgtac
tggttcactgtggagttcgggctgtgcaaacagaatggagaggtgaaggcctacggagcg
gggctgctgtcctcctacggggagctcctgcactccctttctgaggagcccgagatccgg
gccttcgaccctgacacagcggccgtgcagccctaccaggaccagacttaccagcccgtc
tacttcgtgtctgagagcttcagcgatgccaaggacaagctcaggaactacgcctcccgc
atccagcgccccttctctgtgaagtttgacccgtacacgctggccatcgacgtgctggac
agtccccgcgccatccggcgcgccctggacggcgtccaggatgagttgcaggccctggcc
cacgctctgaacgccatcagctag
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