Cebus imitator (Panamanian white-faced capuchin): 108288724
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Entry
108288724 CDS
T08783
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
cimi
Cebus imitator (Panamanian white-faced capuchin)
Pathway
cimi00350
Tyrosine metabolism
cimi00790
Folate biosynthesis
cimi01100
Metabolic pathways
cimi04728
Dopaminergic synapse
cimi04917
Prolactin signaling pathway
cimi05012
Parkinson disease
cimi05030
Cocaine addiction
cimi05031
Amphetamine addiction
cimi05034
Alcoholism
Module
cimi_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
cimi00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
108288724 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
108288724 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
108288724 (TH)
09156 Nervous system
04728 Dopaminergic synapse
108288724 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
108288724 (TH)
09165 Substance dependence
05030 Cocaine addiction
108288724 (TH)
05031 Amphetamine addiction
108288724 (TH)
05034 Alcoholism
108288724 (TH)
Enzymes [BR:
cimi01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
108288724 (TH)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
108288724
NCBI-ProteinID:
XP_037587076
Ensembl:
ENSCCAG00000029578
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MPTPDATAPQAKGFRRAVSELDAKQAEAIMVRGQSPRFIGRRQSLIEDARKEREAAVAAA
AAAASSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETR
PSQRPRAGGPHLEYFVRLEVPRGDLAALLSGVRQVSEDVHSPVEHKVPWFPRKVSELDKC
HHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVY
TKLKGLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSA
RDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASL
GASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPEA
AAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTQAVDVLDSPQAVR
RSLEGVQDELDTLAHALSAIG
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgcctacccccgacgccaccgcaccgcaggccaagggctttcgcagggctgtgtctgag
ctggacgccaagcaggcagaggccatcatggtaagagggcagtccccgaggttcattggg
cggcggcagagcctcatcgaggacgcccgaaaggagagggaggcggcggtggcggcagcg
gcggctgcagcctcctcggagcctggggaccccctggaggccgtggcctttgaggagaag
gaggggaaggcggtgctgaacctgctcttctccccgagggccaccaagccctccgcgctg
tcccgagctgtgaaggtgttcgagacatttgaagccaaaatccaccacctagagacccgg
ccgtcccagaggcctagagcggggggcccccacctggagtactttgtgcgcctggaggta
cccagaggggacctggccgccctgctcagtggtgtgcgccaggtgtcagaggatgtgcac
agccccgtggagcacaaggtcccctggttcccgagaaaagtgtcagagctggacaagtgt
catcacctggtcaccaagttcgaccctgacctggacttggaccacccgggcttctccgac
caggtgtaccgccagcgcaggaagctgattgccgagatcgccttccagtacaggcatggc
gacccgattccccgtgtggagtacaccgctgaggagattgccacctggaaggaggtctac
accaagctgaaggggctgtacgccacccacgcctgcggggagcacctggaagccttcgcg
ctgctggagcgcttcagcggctaccgggaggacaacatcccccagctggaggacgtctcc
cgcttcctgaaggagcgcacgggcttccagctgcggcctgtggccggcctgctgtctgcc
cgggacttcctggcaagcctggccttccgcgtgttccagtgcacccagtacatccgccac
gcgtcctcgcccatgcactccccagagccggactgctgccatgagctgctggggcacgtg
cccatgctggctgaccgcaccttcgcacagttctcccaggacatcggcctggcatccctg
ggggcctcggatgaggaaattgagaagctgtccacgctgtactggttcacggtggagttt
gggctgtgtaagcagaacggggaggtgaaggcctacggcgccgggctgctgtcctcctac
ggggagctcttgcactccctgtctgaggagccagagatccgggccttcgaccccgaagct
gcggccgtgcagccctaccaagaccagacgtaccagtcggtgtacttcgtgtcagagagc
ttcagcgacgccaaggacaagctcaggagctacgcctcacgcatccagcgccccttctcc
gtgaagtttgacccgtacacgcaggccgtggacgtgctggacagcccccaggccgtgcgg
cgctccctggagggtgtccaggacgagctggacaccctggcccacgcactgagtgccatt
ggctag
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