Canis lupus dingo (dingo): 112663223
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Entry
112663223 CDS
T08371
Symbol
TH
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
clud
Canis lupus dingo (dingo)
Pathway
clud00350
Tyrosine metabolism
clud00790
Folate biosynthesis
clud01100
Metabolic pathways
clud04728
Dopaminergic synapse
clud04917
Prolactin signaling pathway
clud05012
Parkinson disease
clud05030
Cocaine addiction
clud05031
Amphetamine addiction
clud05034
Alcoholism
Module
clud_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
clud00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
112663223 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
112663223 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
112663223 (TH)
09156 Nervous system
04728 Dopaminergic synapse
112663223 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
112663223 (TH)
09165 Substance dependence
05030 Cocaine addiction
112663223 (TH)
05031 Amphetamine addiction
112663223 (TH)
05034 Alcoholism
112663223 (TH)
Enzymes [BR:
clud01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
112663223 (TH)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
112663223
NCBI-ProteinID:
XP_025307636
Ensembl:
ENSCAFG00020017377
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All DBs
Position
18:complement(46244546..46252486)
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AA seq
496 aa
AA seq
DB search
MPTPNTASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAASXAAS
SEPGDLLEAAVSKEKDGKAMLNLLFTLRGAKTSSLSRAVKAFETFEAQIHHLETRPAQRP
RAGGPHLEYFVRCEVPSADLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVT
KFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKS
LYVTHACREHLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLA
SLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDE
EIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQP
YQDQTYQSVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLEG
VQDELHTLAHALSAIG
NT seq
1491 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccaacaccgcctcgccgcaggccaagggcttccgcagggctgtctcggag
ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcggcgccagagc
ctcattgaggacgcacgcaaggagcgagagaaagcagaggccgcgtcannggctgcctcc
tcggagcccggagacctcctggaggccgcggtgtccaaggagaaggacgggaaggccatg
ctgaacttgctcttcaccctgcggggtgccaagacctcttcgctgtcccgagccgtgaag
gcatttgagacgtttgaagcccaaatccaccatctggagacccggcccgcccagaggcca
cgggcagggggcccccacctggagtactttgtgcgctgtgaggtgcccagtgctgacctg
cccgccctgctcagctccgtgcgccgggtggcggaggatgtgcgtggtgccggggagaac
aaggtcctctggttcccaaggaaagtttctgagctggacaagtgccaccatctagtcacc
aagtttgaccctgacctggacttggatcacccgggcttctcggaccaggtgtaccgccag
cgcaggaagctgattgcagagatcgcattccaatacaagcatggtgaccccattccccga
gtggagtacacggccgaggagattgccacctggaaggaggtctacaccaccctgaaaagc
ctgtatgtgacccatgcctgccgggagcacctggaggccttccagctgctggagcgcttc
agcgggtaccgtgaggacagcatcccccagctggaggacgtgtcccgcttcctgaaggag
cggacaggcttccagctgcggcccgtggccggtctgctgtccgcaagggacttcctggcc
agcctggccttccgagtgttccagtgcacgcagtacatccggcacgcgtcctcacccatg
cactcccccgagccggactgctgtcatgagctgctggggcacgtgcccatgctggctgac
cggaccttcgctcagttttcccaggacattgggctcgcgtccttgggggcttctgatgag
gaaattgagaagctgtccacgctgtactggttcacagtggagttcgggctgtgcaagcag
aatggtgaggtgaaggcctatggcgctgggctgctgtcctcctacggggagctcctgcac
tccctgtctgaggagcccgagatccgggccttcgacccagacgctgcggccgtgcagcct
taccaggaccagacctaccagtcggtctactttgtgtctgaaagcttcagcgatgccaag
gacaagctcaggaactacgcttcccgcatccaacgccccttctccgtgaagttcgaccca
tatacgctggccatcgacgtgctggacagtccccacgccatccggcgctcgctggagggg
gtccaggacgagctgcacaccctcgcccatgcgctcagcgccatcggctag
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