KEGG   Cryptococcus neoformans var. grubii H99: CNAG_06830
Entry
CNAG_06830        CDS       T08175                                 
Name
(RefSeq) histidinol dehydrogenase
  KO
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Organism
cng  Cryptococcus neoformans var. grubii H99
Pathway
cng00340  Histidine metabolism
cng01100  Metabolic pathways
cng01110  Biosynthesis of secondary metabolites
cng01230  Biosynthesis of amino acids
Module
cng_M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:cng00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    CNAG_06830
Enzymes [BR:cng01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     CNAG_06830
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     CNAG_06830
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     CNAG_06830
SSDB
Motif
Pfam: Histidinol_dh PRA-CH PRA-PH BFN_dom WDR90_beta-prop_4th
Other DBs
NCBI-GeneID: 23889997
NCBI-ProteinID: XP_012049578
UniProt: J9VJK6
LinkDB
Position
5:complement(134047..137045)
AA seq 852 aa
MSTPPFLPLVTPRDTTLLPSLALIAPVLVPSDHLEQIRQSLPANASYYVQASDNDDLIAL
LDGGAEKLVVTPQQLEAGGAGIPKERLILRVCEEELSTSKHFAQQTGGILIISSVPHSAK
SLALPGVDVFLQLPEVQPLRILNLIRSSRPSSYVIPSSYLSIESSTTAEKISIPEAFLAP
IVSDRPDGLFPTIVSSYSHSTTPLGLVYSSIESVKESILTQKGVYQSRKHGLWRKGETSG
AVQQVTGIKLDCDNDALIFEVVQHGSGFCHLPQSTCFGNLSGIAKLSDTLTSRLASAPEA
SYTKRLFTDEKLLKNKIMEEAEELCDAQTKEEVAFEAADLVYFALTRCVSKGVSWRDVEA
ALDKKALKVTRRKGDAKPKWEGKTKEVVNENGEAKTTVPEPTKLPEPESENAPIKMRAVT
LSTLSALEQKDLLLRPVLNSLAMIDKVKPIVERVRQEGDAGLKAMTKQFDRADLSSNVLL
PPFETPGEDVLPKDVREAIDVAYNNVKEFHQAQNEKEPLVVETMPGVTCSRFARPIARVG
VYVPGGTAILPSTAIMLGVPAQVAGCKTIVLATPPRQDGSISPEVLYVAKLTGVTCILKA
GGAQAVGAMAYGTDEVPKVDKIFGPGNQWVTAAKMLVQNDTDALVAIDMPAGPSEVLVIA
DHTANPIFVASDLLSQAEHGVDSQVILLAINLTPEHLAAIEAEIDRQARALPRVKIAREA
IKKSVTVEVKDLEEAVKFSNEYAPEHLILHLEKAEEVVAEIENAGSVFVGPFSPESCGDY
ASGTNHTLPTNGFARQFSGVNTLSFQKHITSQTVSAEGLKKLGPYVVRLAEREGLEAHAN
AVRVRLAELNKQ
NT seq 2559 nt   +upstreamnt  +downstreamnt
atgagcacgccccctttcctccccctcgttacccctcgagacaccactctccttccctcc
ctcgctcttatcgctcccgtccttgtcccctccgaccatcttgaacaaatccgccaatca
ttgcctgcaaatgcgtcatactacgtccaagcaagcgacaacgacgacttgatcgccctc
ctcgacggcggcgccgagaagctcgtcgtcaccccccaacaacttgaggctggtggcgcg
ggaattcctaaggaaagacttattcttcgagtctgtgaggaagagctctctacttccaag
cactttgcccagcagacaggtggtatcctcattatctcttctgtccctcacagtgccaag
tcgctcgctctccctggtgtggacgtctttctccaactccctgaggtccagcctcttaga
atcctaaatcttatcagatcctctcgcccttcttcctacgtcattccttcttcatacctt
tccatcgagtcctccactaccgccgagaaaatctccatccccgaagctttccttgcccct
atcgtctccgaccgccccgatggtcttttccccaccatcgtgtcctcttacagccactct
accaccccccttggtttggtctactcttccattgaaagtgtcaaggagtcgatccttaca
cagaaaggcgtttaccagtctaggaagcacggtttatggaggaagggcgagactagcggt
gcggtgcaacaggtcaccggcatcaagctcgactgtgataacgatgctttgatctttgag
gtcgtccagcacggttctggtttttgccacctccctcagtcaacatgttttggtaacctt
tccggtatcgccaagctctcagacacccttacttcccgtcttgcttctgcgcccgaagcc
tcctacaccaagcgacttttcacagatgaaaagcttttgaagaacaagatcatggaagaa
gccgaagagctctgtgatgctcagactaaagaagaggttgcgtttgaggcggctgatttg
gtttactttgccttgacaaggtgtgtcagcaaaggggtgagttggagagatgttgaggca
gctttagacaagaaggcgttgaaggtgacaagaaggaagggtgatgccaaacctaagtgg
gagggaaagaccaaagaggttgtaaatgaaaatggagaagccaagactaccgttcccgaa
ccaaccaagcttcccgagcccgaatctgaaaatgcccctatcaagatgcgagccgttacc
ctctctaccctctccgcccttgagcagaaagaccttctcctccgacccgttcttaactca
ctcgccatgattgataaggtcaaacccatcgtcgagcgtgtccgacaggaaggcgacgcc
ggtttgaaagccatgaccaagcaattcgaccgtgccgatctttcttccaacgttctcctc
cctcccttcgagaccccaggagaagatgtactgcctaaggatgtgagggaagcgatcgat
gtggcgtataacaatgtcaaagagttccatcaagctcaaaacgaaaaggagccgcttgtg
gtggagactatgcctggcgttacttgttctcgattcgctcgacccatcgcccgagttggt
gtctacgtacccggtggtactgccatcctcccttctacggctattatgctcggcgtcccc
gcccaagtagctggctgtaaaacgattgtcctcgctacccctccccgacaggacggatcc
atctcacctgaagttttgtacgtcgccaagcttaccggcgttacttgtatcttgaaggct
ggtggtgctcaggctgtgggcgccatggcctatggaacggatgaagtgcccaaggtggat
aagatctttggccctggaaaccagtgggttactgcggccaagatgttagtgcagaatgat
acggatgcattggtagctatcgacatgcctgccggtccttctgaagtcctcgtcatcgcc
gatcacactgccaaccccatcttcgtcgcttccgacctcctctctcaagccgaacacggc
gtcgactcccaggtcatcctcctcgccatcaatctcactcctgagcaccttgctgctatc
gaagccgaaattgatcgacaagcccgggcgctcccccgtgtcaagattgcaagggaggct
atcaagaagagtgtcaccgttgaggtcaaggatctggaagaggctgtcaagtttagcaat
gagtatgctccagagcacttgattttgcacctcgagaaggcggaagaggttgtagctgag
attgagaatgccggtagcgtgtttgttggtcccttctctcccgaatcatgcggtgattac
gcctctggtaccaaccacacccttcccactaacggctttgcccgtcaattctctggcgtc
aacactctttctttccaaaaacacattacctcccagacagtcagtgcggaagggttgaag
aagttgggtccgtatgtcgtcaggttggctgagagggaagggttggaggcgcacgcgaat
gctgtgagagtcaggttggcagagttgaacaagcaatag

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