Cavia porcellus (domestic guinea pig): 100727788 Help Entry 100727788         CDS       T07777                                  Name (RefSeq) steroid 21-hydroxylase   KO K00513   steroid 21-monooxygenase [EC:1.14.14.16] Organism cpoc  Cavia porcellus (domestic guinea pig) Pathway cpoc00140   Steroid hormone biosynthesis cpoc01100   Metabolic pathways cpoc04925   Aldosterone synthesis and secretion cpoc04927   Cortisol synthesis and secretion cpoc04934   Cushing syndrome Module cpoc_M00108   C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone cpoc_M00109   C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone Brite KEGG Orthology (KO) [BR:cpoc00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     100727788  09150 Organismal Systems   09152 Endocrine system    04925 Aldosterone synthesis and secretion     100727788    04927 Cortisol synthesis and secretion     100727788  09160 Human Diseases   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100727788  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:cpoc00199]     100727788 Enzymes [BR:cpoc01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor     1.14.14.16  steroid 21-monooxygenase      100727788 Cytochrome P450 [BR:cpoc00199]  Cytochrome P450, animal type   CYP21 family    100727788 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  p450 Motif Other DBs NCBI-GeneID:  100727788 NCBI-ProteinID:  XP_003473789 LinkDB All DBs Position Unknown AA seq 492 aa AA seqDB search MLLLGLLLLVLLASARLLRAQWMHRSLRLPPLAPGFLHLLHPNLPSHLLSLTRELGPIYR LHYGLQEVVVLNSKQAIEEAMLRKWADFAGRPQLLSYKLVCQQYPDLSLGDYSLLWKAHK KLSRSALLLGTRNIMEPVVQQLAQEFCERLGAQAGAPVDIYHEFSLLTCSIICCLSFGSK EDNLIRSIYSCVQDLMTAWDHWSVQILELLPFLRFLPNPGVWRLKQLVAARDHIVGQQLR QHKEQLMAGQWRDMMDYMLQEVRQPRKDWGSRQLKEGHVHMAVVDFFIGGTTTTATTLSW AVAFLLHHPEIQQRLQEELDLELGPGLLASPLPYKERSRLPLLNATITEVLRLRPVVPLA LPHRTTRPSSISGYDIPKDTVIIPNIQGAHLDPSVWERPHEFRPDRFLQPGKGPRELAFG CGARVCLGEPLARLELFVVLSRLLQAFTLLPLEGALPSLEPQPYSGVNLQMQPFRVRLQP RGPGAPRPGQCQ NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgctgctccttgggctgctgctgctggtactgctggccagtgcccgcctgctgcgggcc cagtggatgcataggagcctgcgccttccacctctggccccaggcttcctgcacctcctg caccccaacctccctagtcacctgctcagcctcacccgggagcttgggcccatctatagg ctgcactatgggcttcaagaggtggtagtgctgaactccaagcaggccattgaagaggcc atgctcaggaagtgggcagacttcgccggcagaccccagctgctgtcctacaagctggtg tgccagcagtacccggacctttcgctgggggactactccctgctctggaaggcccacaag aagctctcgcgctcggcccttctgctgggcacccgcaatatcatggagccggtggtgcag cagttagcccaggagttctgcgagcgcctgggagcccaggctggtgcccccgtggacatc taccacgagttctccttgctcacctgcagcatcatctgctgcctctcctttggaagcaag gaggacaacctgattcggagcatttacagctgtgtacaggacttgatgaccgcctgggac cactggtctgtccaaattctggagctacttccctttctcaggttcctccccaacccaggc gtctggaggctgaagcagttggtggcggccagggatcacattgtagggcagcagctgagg cagcacaaggagcagctgatggccgggcagtggagggacatgatggactacatgctccag gaggtgcggcagcccaggaaggactggggctccagacagctcaaggagggccacgtgcac atggctgtggtggacttcttcatcggtggcaccacgaccacagccaccactctctcctgg gccgtggctttcctgctgcaccatccagagatccagcaacgactccaagaagagctggac ctcgagctgggccctggtcttcttgcctccccacttccatacaaggagcgctctcggctg cccctgctcaacgccaccatcaccgaggtgctgcgcctacggcctgtggtgcccctggcc ctgccccatcgtaccactcgacccagcagcatctccggctacgacatccccaaggacaca gtgattatccccaacatccaaggtgcccacctggacccgtcggtgtgggagcggccccac gagttccggccagaccgcttcctgcagccgggcaagggcccccgagagctggccttcggc tgcggggcgcgcgtgtgcctgggggagcccctggcgcggctggaactcttcgtggtgctg agccgccttctccaggccttcacgctgctgccgctggagggcgccctgccctccctagaa ccccagccctacagcggcgtcaacctccaaatgcagccctttcgggtgcggctgcagccc cgaggcccgggggctccgcgcccgggccagtgccagtga

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