Cavia porcellus (domestic guinea pig): 100734150
Help
Entry
100734150 CDS
T07777
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
cpoc
Cavia porcellus (domestic guinea pig)
Pathway
cpoc00350
Tyrosine metabolism
cpoc00790
Folate biosynthesis
cpoc01100
Metabolic pathways
cpoc04728
Dopaminergic synapse
cpoc04917
Prolactin signaling pathway
cpoc05012
Parkinson disease
cpoc05030
Cocaine addiction
cpoc05031
Amphetamine addiction
cpoc05034
Alcoholism
Module
cpoc_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
cpoc00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
100734150 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100734150 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
100734150 (Th)
09156 Nervous system
04728 Dopaminergic synapse
100734150 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100734150 (Th)
09165 Substance dependence
05030 Cocaine addiction
100734150 (Th)
05031 Amphetamine addiction
100734150 (Th)
05034 Alcoholism
100734150 (Th)
Enzymes [BR:
cpoc01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
100734150 (Th)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
100734150
NCBI-ProteinID:
XP_003468387
Ensembl:
ENSCPOG00000012591
UniProt:
H0VLS4
LinkDB
All DBs
Position
Unknown
AA seq
498 aa
AA seq
DB search
MPTPSTAAPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAEAAAAAAV
ASSEPGDPLEAVVFEEKEGRAVLNLLFSLRGSKPSPLSRAVKVFETFEAKIHHLETRPAP
RPQAGGPCLEYFVRFEVPRGDLPALLSSVRRVSDDVRSPKEDKVPWFPQKVAELDKCHHL
VTKFEPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGEPIPLVEYTAEEIATWKEVYTTL
KGLYATHACREHLEAFQLLERFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDF
LASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGAS
DEEIEKLSTLYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEIRAFDPEAAAV
QPYQDQTYQSVYFVSESFSDAKAKLRSYASRIQRPFSVKFDPYTLAIDVLDNPHAIQRSL
EGVQDELHTLVHALGAIS
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccagcaccgccgcgccgcagcctaagggtttccgaagggccgtctccgag
ctggatgccaagcaagccgaggccatcatgtccccccggttcatcgggcgtcggcagagc
ctcattgaagatgctcgcaaggagcgggaggcagctgaggccgcagcggcagctgcagtg
gcctcctcagagcctggggaccccctggaggcggttgtcttcgaggaaaaggaggggaga
gctgtgctgaacctgctcttctctcttcggggctccaagccctctccgctgtcccgggca
gtcaaggtgttcgagacatttgaagccaaaatacaccacctggagacccgtccagcccca
aggccacaagcaggtggcccttgcctggaatactttgtacgctttgaggtgccccgtggg
gacctgcctgccctgcttagctctgtgcgtcgggtgtcagatgatgtgcgcagtcccaag
gaggacaaagtcccctggttcccacaaaaggtggcagagctggacaagtgtcaccacctg
gtcaccaagtttgaacctgacctggacctggaccatccgggtttctcagaccaggtgtac
cgccagcgcaggaagctgattgctgagatcgccttccagtacaagcacggtgagccgatt
ccactggtggagtacacagctgaggagattgccacctggaaggaagtctacactaccctg
aagggcctctacgccactcatgcctgccgggagcacctggaggccttccagctgctggag
cgcttctgtggctaccgtgaggacagcatcccgcagctggaagatgtgtcgcggttcctc
aaggagcggacaggcttccagctgcggcccgtggctggcctgctgtctgcacgggacttc
ctggccagcctggccttccgagtgttccagtgcacccagtacatccgccacgcctcctcg
cccatgcactcacctgagccggattgctgccatgagctgctggggcacgtgcccatgcta
gctgaccgcacgttcgctcagttttcccaggacatcggccttgcatctctgggggcctct
gatgaggaaattgagaagttgtccacgttatactggttcacggtggagttcgggctgtgc
aaacagaatggagagttgaaggcttatggcgccgggttgctgtcctcctatggggagctc
ctgcactccctgtctgaggagcctgagatccgggcctttgaccctgaggctgctgctgtc
cagccctaccaagatcagacctaccagtccgtctacttcgtgtcggagagcttcagtgat
gcaaaggccaagctcaggagctatgcctctcgaatccagcgccctttctctgtgaagttt
gacccctacaccctggccatcgatgtgctggacaatccccacgccatccagcgatccctg
gagggtgtccaggatgagctgcacaccctggtccacgcactgggtgccatcagctag
DBGET
integrated database retrieval system