KEGG   Carlito syrichta (Philippine tarsier): 103271305
Entry
103271305         CDS       T07836                                 
Name
(RefSeq) steroid 21-hydroxylase isoform X1
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
csyr  Carlito syrichta (Philippine tarsier)
Pathway
csyr00140  Steroid hormone biosynthesis
csyr01100  Metabolic pathways
csyr04925  Aldosterone synthesis and secretion
csyr04927  Cortisol synthesis and secretion
csyr04934  Cushing syndrome
Module
csyr_M00108  C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
csyr_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:csyr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    103271305
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    103271305
   04927 Cortisol synthesis and secretion
    103271305
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103271305
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:csyr00199]
    103271305
Enzymes [BR:csyr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     103271305
Cytochrome P450 [BR:csyr00199]
 Cytochrome P450, animal type
  CYP21 family
   103271305
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 103271305
NCBI-ProteinID: XP_008066964
Ensembl: ENSTSYG00000013158
VGNC: 82912
UniProt: A0A1U7U3Y9
LinkDB
Position
Unknown
AA seq 496 aa
MLFPGLLLLLLTLLVSARLLWGWWKLRSLRLPPFAPGFLHLLQPNLPIHLLGLTQKFGPI
YRLRFGLQDVVVLNSKRTIEEAMVRKWEDFAGRPETLSYKLVSQDYPDLSLGDYSLLWKA
HKKLTRSALLLGIRNSLEPMVEQLAQEFCERMRAQAGAPVAIQKEFSLLTCSIICYLTFG
DKIKEDNLVHAYHDCVQEVMDAWNHWSVQIVDVIPFLRFFPNPGLQRLKQIMEKRDRMVE
KQLRQHKDSLVTGHWRDLMDYMLQGVALPAVEEGPGQLLEGHVHMAVVDILIGGTETTAT
TLSWAVAFLLHHPEIQQRLQEELDRELGPEGSGSPVSYKDRGRLPLLNATIAEVLRLRPV
VPLALPHRTTRHSSILGYDIPEGTIIIPNLQGAHLDETVWEQPHKFWPDRFLEPGTSPRA
LAFGCGARVCLGEPLARLELFVVLARLLQGFTLLPLGGALPSLQPQPHFGVNLLMQPFEV
RLQPRGVGARVLGQRQ
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgctgttccctgggctgctgctgctgctgctgaccctgctggtcagtgcccgcctgctg
tggggctggtggaagctcaggagcctccgcctcccgccttttgctccaggtttcctgcac
ctgctgcagcccaacctccccatccatctgcttggcctgactcagaaattcgggcctatc
tacaggctccgcttcggcctgcaagatgtggtggtgctgaactccaaaagaaccattgag
gaagccatggtcagaaagtgggaggactttgctggcagacctgagacgctttcctacaaa
ctggtgtctcaggactacccagacctgtcactaggggactactccctgctctggaaggcc
cacaagaaactcacccgttcagccctgctgctgggcattcgcaactccctggagcccatg
gtggaacagctggcccaggaattctgtgagcgcatgagagcccaggccggcgcccctgtg
gccatccagaaggaattttctctccttacctgcagcatcatctgttacctcacctttgga
gacaagatcaaggaggataacttagtacatgcctatcatgactgtgtccaggaagtgatg
gatgcctggaaccactggtcggtccaaattgtggatgtaattccctttctcaggtttttc
cccaatccaggtctccagaggctgaagcagatcatggagaagagggaccgcatggtagaa
aagcagctgaggcagcacaaggacagcctggtgacaggccactggagggacctgatggac
tacatgctccaaggagtggcactgccggcagtggaagagggccctggacagctcctagaa
gggcatgtacatatggctgtggtggacattctcattggtggcactgagaccacagcgacc
actctctcctgggctgtagctttcttgcttcaccaccctgagattcagcagcgactgcag
gaagagctagaccgcgaactgggccccgagggctctggctccccagtctcctacaaggac
cgtgggcggctgcccttgctcaacgccaccatcgccgaggtgctgcgcctgcggcctgtg
gtgcccttggccttgccccaccgcaccacgcggcacagcagcatcctgggctatgacatc
cccgagggcacaatcatcatccccaacctccaaggcgcccacctggacgaaacggtctgg
gagcagccgcacaagttctggcccgaccgcttcctggagccgggcacgagccccagggcg
ctggcctttggctgcggagcgcgcgtgtgcctgggcgagccgctggcgcgcctggagctc
tttgtggtgctggcgcggctgctgcagggcttcacgctgctgccgctcgggggcgccctg
ccctccctgcagccccagccccacttcggcgtcaacctcctgatgcagcctttcgaggtg
cggttgcagccccgaggcgtgggggcccgcgtcctgggccagcgccagtga

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