Delphinus delphis (saddleback dolphin): 132429319
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Entry
132429319 CDS
T11117
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ddp Delphinus delphis (saddleback dolphin)
Pathway
ddp00350
Tyrosine metabolism
ddp00790
Folate biosynthesis
ddp01100
Metabolic pathways
ddp04728
Dopaminergic synapse
ddp04917
Prolactin signaling pathway
ddp05012
Parkinson disease
ddp05030
Cocaine addiction
ddp05031
Amphetamine addiction
ddp05034
Alcoholism
Module
ddp_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ddp00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
132429319 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
132429319 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
132429319 (TH)
09156 Nervous system
04728 Dopaminergic synapse
132429319 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
132429319 (TH)
09165 Substance dependence
05030 Cocaine addiction
132429319 (TH)
05031 Amphetamine addiction
132429319 (TH)
05034 Alcoholism
132429319 (TH)
Enzymes [BR:
ddp01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
132429319 (TH)
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Other DBs
NCBI-GeneID:
132429319
NCBI-ProteinID:
XP_059873554
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Position
8:108899025..108906202
AA seq
493 aa
AA seq
DB search
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARNERQKAEAAAAAAA
AAAEPGEALGGRAGKAALNLLFTLRATKPPALSRAVKVFETFEAQIHHLETRPAQKPQAG
GLHLEYFVRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFD
PDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYTTLRGLYA
THACREHLEAFELLEHFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLA
FRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIE
KLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQD
QTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRALDGVRD
ELHALTHALSAIS
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccaacgctgcctcaccgcaagccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaggccatcatgtccccacgcttcgtcgggaggcggcagagc
ctcatccaggatgcccgcaacgagcgacagaaggcggaggccgccgccgccgccgctgct
gcagccgcggagccgggcgaggccctggggggacgggccgggaaggccgcgctgaatctc
ctcttcaccctgcgggccaccaagccccccgcgctgtcccgggctgtgaaggtgtttgag
acatttgaagcccaaatccaccacctggagacccggcccgcccagaagccgcaggcaggg
ggcctgcacctggagtacttcgtgcgctgtgaggtacccagcgccgccctgcccaccctg
ctcagctcccttcgccgcgtggccgaagatgtgcggggcgctggggagaacaaggtcctc
tggttcccaaggaaagtttctgagctggacaagtgtcaccacctggtcaccaagtttgac
cctgacctggacttggaccatccgggcttctcggaccaggtgtaccgccagcgcaggaag
ctgattgctgagatcgccttccagtacaagcaaggcgaccctattccccacgtggagtac
acggccgaggagactgccacctggaaggaggtctacaccacgctgcggggcctctacgcc
acccacgcgtgccgggaacacctggaggctttcgagctgctggagcacttctgcgggtac
cgggaggacagcatcccccagctggaggacgtctcccgcttcctgaaggagcggaccggc
ttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctggcc
ttccgcgtgttccagtgcacccagtacatccgccatgcctcctcacccatgcactccccc
gagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccggaccttc
gcccagttctcccaggacatcggcctcgcatccctgggggcatcggacgaagaaattgag
aagctgtccacgctgtactggttcaccgtggagtttgggctgtgcaaacagaacggcgag
gtgaaggcctacggagcggggctgctgtcctcctatggggagctcctgcattccctgtct
gaggagcccgagatccgggccttcgaccccgacgcagcggccgtgcagccctaccaggac
cagacttatcaacctgtctacttcgtgtctgagagcttcagcgacgccaaggacaaactc
aggagctatgcctcccgcatccagcgccccttctccgtgaagttcgacccatacacgctg
gccatcgatgtgctggacagcccccacgccatccgacgcgccctggatggtgtccgggac
gagctgcacgccctcacccacgccctgagcgccatcagctag
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