Delphinapterus leucas (beluga whale): 111173401 Help Entry 111173401         CDS       T05885                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle01524   Platinum drug resistance dle04010   MAPK signaling pathway dle04115   p53 signaling pathway dle04148   Efferocytosis dle04210   Apoptosis dle04215   Apoptosis - multiple species dle04623   Cytosolic DNA-sensing pathway dle04650   Natural killer cell mediated cytotoxicity dle04657   IL-17 signaling pathway dle04668   TNF signaling pathway dle04726   Serotonergic synapse dle04932   Non-alcoholic fatty liver disease dle04933   AGE-RAGE signaling pathway in diabetic complications dle04936   Alcoholic liver disease dle05010   Alzheimer disease dle05012   Parkinson disease dle05014   Amyotrophic lateral sclerosis dle05016   Huntington disease dle05020   Prion disease dle05022   Pathways of neurodegeneration - multiple diseases dle05132   Salmonella infection dle05133   Pertussis dle05134   Legionellosis dle05145   Toxoplasmosis dle05146   Amoebiasis dle05152   Tuberculosis dle05160   Hepatitis C dle05161   Hepatitis B dle05162   Measles dle05163   Human cytomegalovirus infection dle05164   Influenza A dle05165   Human papillomavirus infection dle05167   Kaposi sarcoma-associated herpesvirus infection dle05168   Herpes simplex virus 1 infection dle05169   Epstein-Barr virus infection dle05170   Human immunodeficiency virus 1 infection dle05200   Pathways in cancer dle05203   Viral carcinogenesis dle05205   Proteoglycans in cancer dle05206   MicroRNAs in cancer dle05210   Colorectal cancer dle05222   Small cell lung cancer dle05416   Viral myocarditis dle05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:dle00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     111173401 (CASP3)    04668 TNF signaling pathway     111173401 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     111173401 (CASP3)   09143 Cell growth and death    04210 Apoptosis     111173401 (CASP3)    04215 Apoptosis - multiple species     111173401 (CASP3)    04115 p53 signaling pathway     111173401 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     111173401 (CASP3)    04650 Natural killer cell mediated cytotoxicity     111173401 (CASP3)    04657 IL-17 signaling pathway     111173401 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     111173401 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     111173401 (CASP3)    05206 MicroRNAs in cancer     111173401 (CASP3)    05205 Proteoglycans in cancer     111173401 (CASP3)    05203 Viral carcinogenesis     111173401 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     111173401 (CASP3)    05222 Small cell lung cancer     111173401 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     111173401 (CASP3)    05161 Hepatitis B     111173401 (CASP3)    05160 Hepatitis C     111173401 (CASP3)    05164 Influenza A     111173401 (CASP3)    05162 Measles     111173401 (CASP3)    05168 Herpes simplex virus 1 infection     111173401 (CASP3)    05163 Human cytomegalovirus infection     111173401 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     111173401 (CASP3)    05169 Epstein-Barr virus infection     111173401 (CASP3)    05165 Human papillomavirus infection     111173401 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     111173401 (CASP3)    05133 Pertussis     111173401 (CASP3)    05134 Legionellosis     111173401 (CASP3)    05152 Tuberculosis     111173401 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     111173401 (CASP3)    05145 Toxoplasmosis     111173401 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     111173401 (CASP3)    05012 Parkinson disease     111173401 (CASP3)    05014 Amyotrophic lateral sclerosis     111173401 (CASP3)    05016 Huntington disease     111173401 (CASP3)    05020 Prion disease     111173401 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     111173401 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     111173401 (CASP3)    05416 Viral myocarditis     111173401 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     111173401 (CASP3)    04932 Non-alcoholic fatty liver disease     111173401 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     111173401 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     111173401 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:dle01002]     111173401 (CASP3) Enzymes [BR:dle01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      111173401 (CASP3) Peptidases and inhibitors [BR:dle01002]  Cysteine peptidases   Family C14: caspase family    111173401 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  111173401 NCBI-ProteinID:  XP_022426661 UniProt:  A0A2Y9N0H4 LinkDB All DBs Position Unknown AA seq 412 aa AA seqDB search MENNENSVDSKSIKTSETKILHGSKSMDSGISLDYSYKMDYPERGLCIIINNKNFHESTG MACRSGTDVDAANLWETFTNLKYEVRNKNDLTCEEILELMYSVSKEDHSKRSSFICVLLS HGEEGKIFGTNGPVDLKKLTGFFRGDCCISLTGKPKLFVIQACRGTELDCGIETDSGVED DMACQKIPVEADFLYAYSTAPGSRKQSSSSSYSWRNEVGSTCPWCCVWVAANIHEQEDPQ GESGLQASLQARSDCVSMPQSWATGKPNDDVAFRNSKTKWRFCGLESRHSGARSSGQGPT KLKSRCPWAVFSSGGLTQEETISRLIKVIGRTQFLMAVFWLTVSRTSPSATTSHPRVLAS RAPLQAVHDMLFAFRPAGGSLTSNISSLQRRPRPPFEVFTCSGQAQPGSSPF NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt atggagaacaatgaaaattcagtggattcaaaatccattaaaacttcagagacaaagatc ttacatggaagcaaatcaatggactctggaatatccttggactatagttacaaaatggat tatcctgaaaggggtttatgtataataattaataataagaactttcatgaaagtactggg atggcatgtcggtctggtacagacgtagatgcagcaaacctctgggaaaccttcacgaac ttgaaatacgaagttaggaataaaaatgatcttacatgtgaagaaattttggaattaatg tacagtgtttctaaagaagatcatagcaaaaggagcagttttatttgcgtgcttctaagc catggcgaggaaggaaaaatttttggaacaaatggacctgtcgatctgaaaaaattaaca ggtttcttcagaggggattgttgtataagcctaactggcaaacctaaacttttcgttatt caggcttgccgaggcacagaactggactgtggtattgagacagacagtggtgttgaggat gacatggcctgtcagaaaataccggttgaggcggacttcttgtatgcatattctacagca cctggatccagaaagcaaagcagcagcagctcctatagctggcggaatgaagtcgggagc acctgtccatggtgttgtgtgtgggtagcagcaaacatacatgagcaagaagacccacaa ggagagtctgggctccaggcatcgctccaagcaaggagtgactgcgtgagcatgccacag agttgggcaactgggaagccgaatgatgatgtggcttttaggaactcaaaaacaaagtgg aggttttgtggtctggagtccaggcacagtggagctaggtcctcaggtcaggggccaacc aagctgaaatcaaggtgcccgtgggctgtgttctcatctggaggtttgactcaggaagaa accatttccaggctcattaaagttattggtagaactcagttccttatggctgttttctgg ctgactgtcagccggacatcaccctcagcaactacgagccaccctcgggtcctcgcctcg agggcccctttacaggcggttcatgacatgctgtttgcttttaggccagcaggaggatct ctcacttcaaatatctcctccctccagagaaggcccaggcccccttttgaggtgttcact tgctcaggtcaggctcagccaggatcatctcccttttga

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