Delphinapterus leucas (beluga whale): 111184074 Help Entry 111184074         CDS       T05885                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism dle  Delphinapterus leucas (beluga whale) Pathway dle00350   Tyrosine metabolism dle00790   Folate biosynthesis dle01100   Metabolic pathways dle04728   Dopaminergic synapse dle04917   Prolactin signaling pathway dle05012   Parkinson disease dle05030   Cocaine addiction dle05031   Amphetamine addiction dle05034   Alcoholism Module dle_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:dle00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     111184074 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     111184074 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     111184074 (TH)   09156 Nervous system    04728 Dopaminergic synapse     111184074 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     111184074 (TH)   09165 Substance dependence    05030 Cocaine addiction     111184074 (TH)    05031 Amphetamine addiction     111184074 (TH)    05034 Alcoholism     111184074 (TH) Enzymes [BR:dle01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      111184074 (TH) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  111184074 NCBI-ProteinID:  XP_022447966 UniProt:  A0A2Y9PRV2 LinkDB All DBs Position Unknown AA seq 492 aa AA seqDB search MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARNERQKAEAAAAAAA ATEPGEALGGRAGKAALNLLFTLRATKPPALSRAVKVFETFEAQIYHLETRPAQKPQAGG PHLEYFVRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDP DLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYTTLRGLYAT HACREHLEAFELLEHFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAF RVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEK LSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEGPEIRAFDPDAAAVQPYQDQ TYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRALDGVRDE LHALTHALSAIS NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgcccacccccaacgctgcctcgccgcaggccaagggcttccgcagggccgtctccgag ctggacgccaagcaggccgaggccatcatgtccccacgcttcgtcgggaggcggcagagc ctcatccaggatgcccgcaacgagcggcagaaggcggaggccgccgccgccgccgccgcc gccacggagccgggcgaggccctggggggacgggccgggaaggccgcgctgaatctcctc ttcaccctgcgggccaccaagccccccgcgctgtcccgggctgtgaaggtgtttgagaca tttgaagcccaaatctaccacctggagacccggcccgcccagaagccgcaggcagggggc ccgcacctggagtacttcgtgcgctgtgaggtacccagcgccgccctgcccaccctgctc agctctcttcgccgcgtggccgaagatgtgaggggcgctggggagaacaaggtcctctgg ttcccaaggaaagtttctgagctggacaagtgtcaccacctggtcaccaagtttgaccct gacctggacttggaccatccgggcttctcggaccaggtgtaccgccagcgcaggaagctg attgctgagatcgccttccagtacaagcaaggcgaccctattccccacgtggagtacacg gccgaggagactgccacctggaaggaggtctacaccacgctgcggggcctctacgccacc cacgcgtgccgggaacacctggaggctttcgagctgctggagcacttctgcgggtaccgg gaggacagcatcccccagctggaggacgtctcccgcttcctgaaggagcggaccggcttc cagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctggccttc cgcgtcttccagtgcacccagtacatccgccatgcctcctcacccatgcactcccccgag ccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccggaccttcgcc cagttctcccaggacattggcctcgcatccctgggggcatcggacgaagaaattgagaag ctgtccacgctgtactggttcaccgtggagtttgggctgtgcaaacagaacggcgaggtg aaggcctacggagcggggctgctgtcctcctatggggagctcctgcattccctgtctgag gggcccgagatccgggccttcgaccccgatgcagcggccgtgcagccctaccaggaccag acttatcaacctgtctacttcgtgtctgagagtttcagcgatgccaaggacaaactcagg agctatgcctcccgcatccagcgccccttctccgtgaagttcgacccatacacgctggcc atcgatgtgctggacagtccccacgccatccgacgcgccctggatggtgtccgggacgag ctgcacgccctcacccacgccctgagtgccatcagctag

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