KEGG   PATHWAY: dme04820
Entry
dme04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Drosophila melanogaster (fruit fly)
Class
Cellular Processes; Cell motility
Pathway map
dme04820  Cytoskeleton in muscle cells
dme04820

Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG10067  Act57B; actin 57B [KO:K05692]
Dmel_CG10119  LamC; lamin C, isoform A [KO:K07611]
Dmel_CG1019  Mlp84B; muscle LIM protein at 84B, isoform C [KO:K09377]
Dmel_CG10497  Sdc; syndecan, isoform A [KO:K16336]
Dmel_CG10540  cpa; capping protein alpha [KO:K10364]
Dmel_CG11326  Tsp; thrombospondin, isoform F [KO:K04659]
Dmel_CG12008  kst; karst, isoform E [KO:K06115]
Dmel_CG12051  Act42A; actin 42A [KO:K05692]
Dmel_CG12908  Ndg; nidogen, isoform A [KO:K06826]
Dmel_CG14622  DAAM; dishevelled associated activator of morphogenesis, isoform D [KO:K04512]
Dmel_CG14808  Scgdelta; sarcoglycan delta, isoform E [KO:K12563]
Dmel_CG14964  MnM; myomesin and myosin binding protein [KO:K12567] [EC:2.7.11.1]
Dmel_CG1539  tmod; tropomodulin, isoform G [KO:K10370]
Dmel_CG1560  mys; myospheroid, isoform C [KO:K05719]
Dmel_CG15792  zip; zipper, isoform A [KO:K10352]
Dmel_CG1651  Ank; ankyrin, isoform E [KO:K09255]
Dmel_CG16858  vkg; viking, isoform B [KO:K06237]
Dmel_CG17158  cpb; capping protein beta, isoform B [KO:K10365]
Dmel_CG17654  Eno; enolase, isoform B [KO:K01689] [EC:4.2.1.11]
Dmel_CG17927  Mhc; myosin heavy chain, isoform O [KO:K17751]
Dmel_CG17952  LBR; lamin B receptor, isoform C [KO:K19532] [EC:1.3.1.70]
Dmel_CG18250  Dg; dystroglycan, isoform A [KO:K06265]
Dmel_CG18290  Act87E; actin 87E, isoform C [KO:K05692]
Dmel_CG1915  sls; sallimus, isoform A [KO:K12567] [EC:2.7.11.1]
Dmel_CG1977  alpha-Spec; alpha spectrin, isoform A [KO:K06114]
Dmel_CG30084  Zasp52; Z band alternatively spliced PDZ-motif protein 52, isoform F [KO:K19867]
Dmel_CG31999  CG31999; uncharacterized protein, isoform C [KO:K17307]
Dmel_CG32138  Frl; Formin-like, isoform A [KO:K23957]
Dmel_CG32626  AMPdeam; AMP deaminase, isoform H [KO:K01490] [EC:3.5.4.6]
Dmel_CG3299  Vinc; vinculin, isoform B [KO:K05700]
Dmel_CG33556  form3; formin 3, isoform A [KO:K23958]
Dmel_CG3399  capu; cappuccino, isoform A [KO:K02184]
Dmel_CG4027  Act5C; actin 5C, isoform D [KO:K05692]
Dmel_CG4145  Col4a1; collagen type IV alpha 1, isoform A [KO:K06237]
Dmel_CG42309  Mlp60A; muscle LIM protein at 60A, isoform F [KO:K09377]
Dmel_CG42677  wb; wing blister, isoform C [KO:K05637]
Dmel_CG42734  Ank2; ankyrin 2, isoform N [KO:K09255]
Dmel_CG45062  CG45062; uncharacterized protein, isoform A [KO:K01539] [EC:7.2.2.13]
Dmel_CG45760  [KO:K01539] [EC:7.2.2.13]
Dmel_CG4843  Tm2; tropomyosin 2, isoform F [KO:K10374]
Dmel_CG4898  Tm1; tropomyosin 1, isoform K [KO:K10373]
Dmel_CG5657  Scgbeta; sarcoglycan beta [KO:K12566]
Dmel_CG5670  Atpalpha; Na pump alpha subunit, isoform A [KO:K01539] [EC:7.2.2.13]
Dmel_CG5870  beta-Spec; beta spectrin, isoform A [KO:K06115]
Dmel_CG6831  rhea; rhea, isoform B [KO:K06271]
Dmel_CG6944  Lam; lamin, isoform B [KO:K07611]
Dmel_CG7107  up; upheld, isoform I [KO:K12046]
Dmel_CG7152  Syn1; Syntrophin-like 1, isoform C [KO:K24064]
Dmel_CG7526  frac; faulty attraction, isoform C [KO:K17307]
Dmel_CG7851  Scgalpha; sarcoglycan alpha, isoform B [KO:K27061]
Dmel_CG8111  Tmem43; transmembrane protein 43 [KO:K27488]
Dmel_CG8663  nrv3; nervana 3, isoform E [KO:K01540]
Dmel_CG9258  nrv1; nervana 1, isoform B [KO:K01540]
Dmel_CG9261  nrv2; nervana 2, isoform F [KO:K01540]
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
dme04512  ECM-receptor interaction
dme04814  Motor proteins
KO pathway
ko04820   

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