KEGG   PATHWAY: ko04820
Entry
ko04820                     Pathway                                
Name
Cytoskeleton in muscle cells
Class
Cellular Processes; Cell motility
Pathway map
ko04820  Cytoskeleton in muscle cells
ko04820

Orthology
K06236  collagen type I alpha
K19720  collagen type III alpha
K19721  collagen type V/XI/XXIV/XXVII, alpha
K08131  collagen type IX alpha
K04660  decorin
K06793  versican core protein
K14211  elastin
K06238  collagen type VI alpha
K16857  thrombospondin 1
K04659  thrombospondin 2/3/4/5
K06825  fibrillin 1
K23342  fibrillin 2/3
K06237  collagen type IV alpha
K17307  fibulin 1/2
K06255  basement membrane-specific heparan sulfate proteoglycan core protein
K06826  nidogen (entactin)
K05717  fibronectin 1
K06257  syndecan 1
K16336  syndecan 2
K16337  syndecan 3
K16338  syndecan 4
K06254  agrin
K08118  biglycan
K07601  desmocollin 2
K07597  desmoglein 2
K12642  plakophilin 2
K10056  junction plakoglobin
K10381  desmoplakin
K07606  vimentin
K07610  desmin
K05637  laminin, alpha 1/2
K06480  integrin alpha 1
K06481  integrin alpha 2
K06476  integrin alpha 2B
K06482  integrin alpha 3
K06483  integrin alpha 4
K06484  integrin alpha 5
K06485  integrin alpha 6
K06583  integrin alpha 7
K06584  integrin alpha 8
K06585  integrin alpha 9
K06586  integrin alpha 10
K06587  integrin alpha 11
K06487  integrin alpha V
K05719  integrin beta 1
K06493  integrin beta 3
K06525  integrin beta 4
K06588  integrin beta 5
K06589  integrin beta 6
K06590  integrin beta 7
K06591  integrin beta 8
K06271  talin
K05700  vinculin
K21073  actinin alpha 2/3
K05692  actin beta/gamma 1
K12315  actin, gamma-enteric smooth muscle
K06265  dystroglycan 1
K12565  alpha-sarcoglycan
K27061  epsilon-sarcoglycan
K12566  beta-sarcoglycan
K12563  delta-sarcoglycan
K12564  gamma-sarcoglycan
K27062  zeta-sarcoglycan
K22194  sarcospan
K10366  dystrophin
K24063  alpha-syntrophin
K24064  beta-syntrophin
K26998  dystrobrevin alpha
K27393  filamin-C
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
K01540  sodium/potassium-transporting ATPase subunit beta
K09259  ankyrin-3
K06114  spectrin alpha, non-erythrocytic (fodrin)
K06115  spectrin beta, non-erythrocytic 1/4/5
K23932  spectrin beta, non-erythrocytic 2
K09377  cysteine and glycine-rich protein
K24220  myosin heavy chain 1/2/3/4/8/13/7B/15
K17751  myosin heavy chain 6/7
K10352  myosin heavy chain 9/10/11/14
K05738  myosin light chain 1
K12749  myosin light chain 3
K12750  myosin light chain 4
K10351  myosin regulatory light chain 2
K12753  myosin regulatory light chain 5
K12754  myosin regulatory light chain 7
K12755  myosin regulatory light chain 9
K12758  fast skeletal myosin light chain 2
K12557  myosin-binding protein C, slow-type
K12558  myosin-binding protein C, fast-type
K12568  myosin-binding protein C, cardiac-type
K24494  myosin-binding protein H
K10354  actin, alpha skeletal muscle
K12314  actin, alpha cardiac muscle
K05865  troponin C, slow skeletal and cardiac muscles
K10371  troponin I, slow skeletal muscle
K10372  troponin T, slow skeletal muscle
K12042  troponin C, skeletal muscle
K12043  troponin I, fast skeletal muscle
K12046  troponin T, fast skeletal muscle
K12044  troponin I, cardiac muscle
K12045  troponin T, cardiac muscle
K10373  tropomyosin 1
K10374  tropomyosin 2
K09290  tropomyosin 3
K10375  tropomyosin 4
K12567  titin [EC:2.7.11.1]
K19875  myotilin
K19879  telethonin
K24066  synaptopodin-2
K18267  nebulin
K25865  nebulette
K26050  myozenin
K23353  PDZ and LIM domain protein 1/2/3/4
K10364  F-actin-capping protein subunit alpha
K10365  F-actin-capping protein subunit beta
K27381  xin actin-binding repeat-containing protein
K24421  nebulin-related-anchoring protein
K22028  myopalladin
K19867  PDZ and LIM domain protein 5/6/7
K10370  tropomodulin
K06273  zyxin
K14365  four and a half LIM domains protein 1
K14380  four and a half LIM domains protein 2
K24414  four and a half LIM domains protein 3
K22030  leiomodin
K21433  ankyrin repeat domain-containing protein 1
K21434  ankyrin repeat domain-containing protein 2
K21438  ankyrin repeat domain-containing protein 23
K23957  formic-like protein
K23958  inverted formin-2
K04512  dishevelled associated activator of morphogenesis
K05740  diaphanous 1
K05741  diaphanous 2
K05745  diaphanous 3
K02184  formin 2
K24495  myomesin
K01689  enolase 1/2/3 [EC:4.2.1.11]
K09255  ankyrin-2
K27382  creatine kinase M-type [EC:2.7.3.2]
K10653  tripartite motif-containing protein 54
K10654  tripartite motif-containing protein 55
K10655  tripartite motif-containing protein 63 [EC:2.3.2.27]
K01490  AMP deaminase [EC:3.5.4.6]
K17531  obscurin-RhoGEF [EC:2.7.11.1]
K08573  calpain-3 [EC:3.4.22.54]
K10388  plectin
K21761  nesprin-3
K19326  nesprin-1
K19346  nesprin-2
K19347  SUN domain-containing protein 1/2
K27488  transmembrane protein 43
K12569  emerin
K19532  Delta14-sterol reductase (lamin-B receptor) [EC:1.3.1.70]
K12641  lamin A/C
K07611  lamin B
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
ko04512  ECM-receptor interaction
ko04814  Motor proteins
LinkDB

DBGET integrated database retrieval system