Dipodomys merriami (Merriam's kangaroo rat): 138818674
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Entry
138818674 CDS
T11079
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
dmer Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00350
Tyrosine metabolism
dmer00790
Folate biosynthesis
dmer01100
Metabolic pathways
dmer04728
Dopaminergic synapse
dmer04917
Prolactin signaling pathway
dmer05012
Parkinson disease
dmer05030
Cocaine addiction
dmer05031
Amphetamine addiction
dmer05034
Alcoholism
Module
dmer_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
dmer00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
138818674 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
138818674 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
138818674 (Th)
09156 Nervous system
04728 Dopaminergic synapse
138818674 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
138818674 (Th)
09165 Substance dependence
05030 Cocaine addiction
138818674 (Th)
05031 Amphetamine addiction
138818674 (Th)
05034 Alcoholism
138818674 (Th)
Enzymes [BR:
dmer01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
138818674 (Th)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
138818674
NCBI-ProteinID:
XP_069865789
LinkDB
All DBs
Position
Unknown
AA seq
498 aa
AA seq
DB search
MPTPGAAAPQPKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIEDARKEREAAAAAAAASS
SSSEPGDPLEAVVFEEKEGMATLTLLFSLRAAKPSSLSRAVKVLETFEAKIHHLETRPAP
RPREGGPHLEYLVRLEVPSGDLAALLSSLRRVAEDLHSVKEDKIPWFPRKVSELDKCHHL
VTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGQPIPHVKYTAEEIATWKEVYTTL
RGLYATHACREHLEAFQLLERFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDF
LASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGVS
DEDIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEIRAFDPDTAAV
QPYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAVDVLDSPRAVQSSL
EGVQDELQILAHALSALG
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccctggtgccgccgcgccccagcccaagggcttccggagggccgtctccgag
ctggacgccaagcaggcggaggccatcatgtccccgaggttcgttgggcggcggcagagt
ctcatcgaggatgcccgcaaggagcgggaggcggctgcggcggctgcggcggcctcctcc
tcctcctcggagcccggggacccgctggaggctgtggtgtttgaggagaaggaagggatg
gccaccctcaccctgctcttctccctgcgggccgccaagccttcttcactgtctcgggct
gtgaaggtgttggagacatttgaagccaaaattcaccacctggaaacgaggccggcccca
agaccccgggagggtggcccccacctggagtacttggtgcgcctggaggtgcccagcggg
gacctggccgccctgctcagctccctgcgccgcgtggcggaggacctgcacagcgtgaag
gaagacaagatcccctggttcccaaggaaagtctccgagctggacaagtgtcaccatctg
gtcaccaagtttgaccctgacctggacttggatcatccgggtttctcggaccaagtgtac
cgccagcgcaggaagctgatagcagagatagcgttccagtataagcagggccagcccatt
ccccacgtgaaatacactgcagaagagatcgccacctggaaggaggtctacaccacgctg
agggggctctacgccacccacgcctgccgggagcacctggaggccttccagctgctggag
cgcttctgcggctaccgcgaggacagcatcccgcagctggaggacgtctcccgcttcctg
aaggagcggacgggtttccagctgcggcctgtggccggcctgctgtctgcccgggacttc
ctggccagcctggccttccgcgtgttccagtgcacgcagtacatccgccacgcctcctct
cccatgcactcgcctgagccggactgctgtcatgagctgctcgggcatgtacccatgctg
gccgaccggacctttgcccagttttcccaggacattggcctcgcatccctgggggtctcg
gatgaggacattgagaaactgtccacagtgtactggttcactgtggagttcgggctgtgc
aagcagaatggagagctgaaggcctatggtgcggggctgctgtcctcctacggggagctc
ctgcactctttgtcagaggagcccgagatccgggccttcgatcccgacacggctgccgtg
cagccgtaccaagaccagacctatcagccggtctacttcgtgtcggagagcttcagcgat
gccaaggacaagctcaggagctatgcttcacggatccagcgccccttctcggtgaagttc
gacccctacacgctggccgtcgacgtgctggacagcccccgcgccgtccagagctccctg
gagggcgtccaggacgagctacagatactggcccatgcgctgagtgcccttggctag
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