KEGG   Dipodomys merriami (Merriam's kangaroo rat): 138827923
Entry
138827923         CDS       T11079                                 
Symbol
Cyp21a2
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
dmer  Dipodomys merriami (Merriam's kangaroo rat)
Pathway
dmer00140  Steroid hormone biosynthesis
dmer01100  Metabolic pathways
dmer04925  Aldosterone synthesis and secretion
dmer04927  Cortisol synthesis and secretion
dmer04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:dmer00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    138827923 (Cyp21a2)
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    138827923 (Cyp21a2)
   04927 Cortisol synthesis and secretion
    138827923 (Cyp21a2)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    138827923 (Cyp21a2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:dmer00199]
    138827923 (Cyp21a2)
Enzymes [BR:dmer01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     138827923 (Cyp21a2)
Cytochrome P450 [BR:dmer00199]
 Cytochrome P450, animal type
  CYP21 family
   138827923 (Cyp21a2)
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 138827923
NCBI-ProteinID: XP_069879608
LinkDB
Position
Unknown
AA seq 485 aa
MLFLGLLLLLILLAGTRLLWGQWEHRNLHLPPLAPGFLHILKPNLPLYLLGLTRKLGPIY
RLRLGLQDVVVLNSKRAIEEALVRKWVDFAGRPQTPSCKGLWLLMDLSLGDYSLLWKAHK
KLTRSALLLGIRDSMEPLVEQLTQEFCERMRAQEGRPVAIQEEFSFLACSIICGLTFGDR
DKSFVNAVYSCVQDLMNAWDHWSVQILNVVPILRFFPNPGLRKLKRIISNRDHIVEQQLR
WHKENLVAGQWKDMTGYMLQRMGQVKGDEGPGELLEGHVHMAMVDLFIGGTETTATTLSW
AVAFLVHHPEIQQRLQNELDLELGSGPLGSHIPHKVRTRLPLLNATIAEVLRLRPVVPLA
LPHRTIRPSSILGYDIPKDTIIIPNLQGANLDETIWERPQEFWPDRFLEPGKSPRVLTFG
CGARVCLGEPLARLELFVVLARLLQTFTLLPLEGAPPSLQPQPFYTVNLQMQPFQVRLQP
RGQGQ
NT seq 1458 nt   +upstreamnt  +downstreamnt
atgctgtttcttgggcttctgttgctgctgatactgctggccggcacccgcctgctatgg
ggccagtgggagcacaggaacctccacctcccgcccctcgccccaggcttcctgcacatc
ctgaagcccaacctccccctctacctgctgggcctcactcggaaacttgggcccatttac
aggctccgtttggggctgcaagatgtggtggtgctgaactccaagagggctattgaggag
gctctggtcagaaagtgggtagactttgccggccgaccccagacaccatcctgtaagggc
ctgtggcttcttatggacctgtcactaggggactactccctgctatggaaggcccacaag
aaactcacccgttctgccctgctgctggggatccgagactccatggagccgctggtggag
cagctgacccaagaattctgtgagcgaatgagggcccaggagggccgccctgtggccatc
caggaggagttctctttcctcgcctgcagcatcatttgcggcctcacctttggagacagg
gacaaatcctttgtaaatgctgtttacagctgtgttcaggatctgatgaacgcttgggac
cactggtccgtccaaattttgaacgtggtccccattctcaggttcttccccaacccaggt
ctccggaagctgaagcggatcatatcaaacagggatcacattgtagagcagcagctgagg
tggcacaaggagaatctggtggcaggccaatggaaggacatgacaggctacatgctccaa
aggatggggcaggtgaaaggggatgagggccctggagagctcctggaagggcacgtgcac
atggccatggtggatctttttatcggtggcactgaaaccacagcaaccactctctcctgg
gctgtggctttcctggttcatcaccctgagattcagcagcgactgcagaatgagctagac
cttgaactggggtctggccccttgggctcccatatcccacacaaggtccgcacgcggctg
cccttgctcaatgccaccattgccgaggtgctccggctacggcctgttgtgcctttggct
ttgccccaccgcaccatccggcccagcagcatcttgggctatgacatccctaaggacaca
atcattatccccaacctccaaggcgcaaatcttgatgagacgatctgggaacggccacag
gaattctggcctgaccgcttcctggagcctggcaagagccccagagtactgacattcggt
tgtggggcccgcgtgtgcctgggagagccactggcccgcttagagctcttcgtggtactg
gcccgcctgctccagactttcacactgctgccacttgagggcgccccgccctcgctgcag
ccccagcccttctacactgtcaacctccagatgcagcccttccaagtgcgcctgcagcct
cggggccagggccagtga

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