Dipodomys ordii (Ord's kangaroo rat): 105989150
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Entry
105989150 CDS
T07834
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
dord
Dipodomys ordii (Ord's kangaroo rat)
Pathway
dord00350
Tyrosine metabolism
dord00790
Folate biosynthesis
dord01100
Metabolic pathways
dord04728
Dopaminergic synapse
dord04917
Prolactin signaling pathway
dord05012
Parkinson disease
dord05030
Cocaine addiction
dord05031
Amphetamine addiction
dord05034
Alcoholism
Module
dord_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
dord00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
105989150 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105989150 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
105989150 (Th)
09156 Nervous system
04728 Dopaminergic synapse
105989150 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105989150 (Th)
09165 Substance dependence
05030 Cocaine addiction
105989150 (Th)
05031 Amphetamine addiction
105989150 (Th)
05034 Alcoholism
105989150 (Th)
Enzymes [BR:
dord01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
105989150 (Th)
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Ortholog
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GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
105989150
NCBI-ProteinID:
XP_012876436
Ensembl:
ENSDORG00000010289
UniProt:
A0A1S3FIU6
LinkDB
All DBs
Position
Unknown
AA seq
532 aa
AA seq
DB search
MPTPGAATPQPKGFRRAVSELDAKQAEAIMVRGPLRPGGRPPAQRQPGVAGGSGRYTCPC
PPQSPRFVGRRQSLIEDARKEREAAAAAAAASSSSSSEPGDPLEAVVFEEKEGMATLTLL
FSLRAAKPSSLSRAVKVLETFEAKIHHLETRPAPRPREGGPHLEYLVRLEVPSGDLAALL
SSLRRVAEDLHSAKEDKIPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKL
IAEIAFQYKQGQPIPNVKYTAEEIATWKEVYTTLRGLYATHACREHLEAFQLLERFCGYR
EDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPE
PDCCHELLGHVPMLADRTFAQFSQDIGLASLGVSDEDIEKLSTVYWFTVEFGLCKQNGEL
KAYGAGLLSSYGELLHSLSEEPEIRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLR
SYASRIQRPFSVKFDPYTLAIDVLDSPRAVQSSLEGVQDELQTLAHALSALG
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccggtgccgccacgccccagcccaagggcttcaggagggccgtctccgag
ctggatgccaagcaggcggaggccatcatggtgagagggccgctgcgacccgggggccgc
ccgccggcccagcgccagcccggggtggcgggtgggagtggcaggtacacctgtccctgt
cccccgcagtccccgaggttcgttgggcggcggcagagtctcatcgaggatgcccgcaag
gagcgggaggcagccgcggcggctgcagcggcctcctcctcctcctcctcggagcccggg
gacccgctggaggccgtggtgtttgaggagaaggaagggatggccaccctcaccctgctc
ttctccctgcgggccgccaagccttcctcactgtctcgggctgtgaaggtgttggagaca
tttgaagccaaaattcaccacctggaaacgaggccggccccgaggccccgggagggtggc
ccccacctggagtacttggtgcgcctggaggtgcccagtggggacctggccgccctgctc
agctccctacgccgcgtggcggaggacctgcacagcgcgaaggaagacaagatcccctgg
ttcccaaggaaagtctccgaactggacaagtgtcaccatctggtcaccaagtttgaccct
gacctggacttggatcatccgggcttctcggaccaagtgtaccgccagcgcaggaagctg
atagcagagatagcgttccagtataagcagggccagcccattcccaacgtgaagtacaca
gcagaagaaatcgccacctggaaggaggtctacaccacgctgagggggctctacgccacc
cacgcctgccgggagcacctggaggccttccagctgctggagcgcttctgcggctaccgc
gaggacagcatcccgcagctggaggacgtctcccgcttcctgaaggagcggacgggtttc
cagctgcggcctgtggccggcctgctgtctgcccgggacttcctggccagcctggccttc
cgcgtgttccagtgcacgcagtacatccgccacgcctcctctcccatgcactcgcctgag
ccggactgctgtcatgagctgctggggcatgtgcccatgctggccgaccggacctttgcc
cagttttcccaggacatcggcctcgcatccctgggggtctcggatgaggacattgagaaa
ctgtccacagtgtactggttcactgtggagttcgggctgtgcaagcagaatggagagctg
aaggcctatggtgcggggctgctgtcctcctacggggagctcctgcactctttgtcagag
gagcctgagatccgggccttcgatcccgacacggctgctgtgcagccgtaccaagaccag
acctaccagccggtctacttcgtgtcagagagcttcagcgatgccaaggacaagctcagg
agctatgcctcacggatccagcgccccttctcggtgaagttcgacccctacacgctggcc
atcgatgtgctggacagcccccgtgccgtccagagctccctggagggcgtccaggacgag
ctacagacgctggcccatgcgctgagtgcccttggctag
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