KEGG   DRUG: ナロキソン塩酸塩
エントリ  
D01340                      Drug                                   
一般名   
ナロキソン塩酸塩 (JP18);
Naloxone hydrochloride (JP18/USP)
商品名   
米国の商品 
  後発品
NALOXONE HCI (HF Acquisition Co. LLC), NALOXONE HYDROCHLORIDE (A-S Medication Solutions), NALOXONE HYDROCHLORIDE (A-S Medication Solutions), NALOXONE HYDROCHLORIDE (Akorn), NALOXONE HYDROCHLORIDE (AuroMedics Pharma LLC), NALOXONE HYDROCHLORIDE (AuroMedics Pharma LLC), NALOXONE HYDROCHLORIDE (AuroMedics Pharma LLC), NALOXONE HYDROCHLORIDE (Baxter Healthcare Corporation), NALOXONE HYDROCHLORIDE (Bryant Ranch Prepack), NALOXONE HYDROCHLORIDE (General Injectables & Vaccines), NALOXONE HYDROCHLORIDE (General Injectables & Vaccines), NALOXONE HYDROCHLORIDE (General Injectables & Vaccines), NALOXONE HYDROCHLORIDE (General Injectables and Vaccines), NALOXONE HYDROCHLORIDE (HF Acquisition Co LLC), NALOXONE HYDROCHLORIDE (HF Acquisition Co LLC), NALOXONE HYDROCHLORIDE (HF Acquisition Co LLC), NALOXONE HYDROCHLORIDE (HF Acquisition Co LLC), NALOXONE HYDROCHLORIDE (HF Acquisition Co. LLC), NALOXONE HYDROCHLORIDE (HF Acquisition Co. LLC), NALOXONE HYDROCHLORIDE (Henry Schein), NALOXONE HYDROCHLORIDE (Henry Schein), NALOXONE HYDROCHLORIDE (Henry Schein), NALOXONE HYDROCHLORIDE (Henry Schein), NALOXONE HYDROCHLORIDE (Hikma Pharmaceuticals USA), NALOXONE HYDROCHLORIDE (Hospira), NALOXONE HYDROCHLORIDE (Hospira), NALOXONE HYDROCHLORIDE (International Medication Systems), NALOXONE HYDROCHLORIDE (International Medication Systems), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Mylan Institutional LLC), NALOXONE HYDROCHLORIDE (Padagis Israel Pharmaceuticals), NALOXONE HYDROCHLORIDE (Proficient Rx LP), NALOXONE HYDROCHLORIDE (Somerset Therapeutics), NALOXONE HYDROCHLORIDE (Somerset Therapeutics), NALOXONE HYDROCHLORIDE (A-S Medication Solutions), NALOXONE HYDROCHLORIDE (Quality Care Products), NALOXONE HYDROCHLORIDE (Sandoz), NALOXONE HYDROCHLORIDE (Civica), NALOXONE HYDROCHLORIDE (Hikma Pharmaceuticals USA), NALOXONE HYDROCHLORIDE (Hikma Pharmaceuticals USA), NALOXONE HYDROCHLORIDE (Medical Purchasing Solutions)
組成式   
C19H21NO4. HCl
質量    
363.1237
分子量   
363.8353
構造式   
Simcomp   
クラス   
鎮痛薬
 DG01586  オピオイド受容体拮抗薬
コード   
薬効分類: 2219
ATCコード: A06AH04 V03AB15
化学構造グループ: DG01155
商品 (DG01155): D01340<JP/US> D11620<US>
商品 (mixture): D10250<US>
効能    
呼吸促進薬, オピオイド受容体拮抗薬
コメント  
ノルモルフィン誘導体
麻薬拮抗薬
ターゲット 
OPRM1 [HSA:4988] [KO:K04215]
OPRK1 [HSA:4986] [KO:K04214]
OPRD1 [HSA:4985] [KO:K04213]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa05032  モルヒネ依存症
構造マップ 
map07039  麻薬性鎮痛剤
map07224  オピオイド受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  22  呼吸器官用薬
   221  呼吸促進剤
    2219  その他の呼吸促進剤
     D01340  ナロキソン塩酸塩 (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 A 消化管と代謝作用
  A06 便秘薬
   A06A 便秘薬
    A06AH 末梢性オピオイド受容体拮抗薬
     A06AH04 ナロキソン
      D01340  ナロキソン塩酸塩 (JP18) <JP/US>
 V その他
  V03 その他すべての治療用製剤
   V03A その他すべての治療用製剤
    V03AB 解毒剤
     V03AB15 ナロキソン
      D01340  ナロキソン塩酸塩 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗中毒薬/物質乱用治療薬
  オピオイド遮断薬
   ナロキソン
    D01340  ナロキソン塩酸塩 (JP18)
医薬品グループ [BR:jp08330]
 鎮痛薬
  DG01586  オピオイド受容体拮抗薬
   DG01155  ナロキソン
    D01340  ナロキソン塩酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   オピオイド
    OPRM1
     D01340  ナロキソン塩酸塩 (JP18) <JP/US>
    OPRK1
     D01340  ナロキソン塩酸塩 (JP18) <JP/US>
    OPRD1
     D01340  ナロキソン塩酸塩 (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D01340  ナロキソン塩酸塩
医薬品グループ [BR:jp08330]
 鎮痛薬
  DG01586  オピオイド受容体拮抗薬
   DG01155  ナロキソン
リンク   
CAS: 357-08-4
PubChem: 7848403
LigandBox: D01340
日化辞: J219.954H
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