KEGG   DRUG: ロスバスタチンカルシウム
エントリ  
D01915                      Drug                                   
一般名   
ロスバスタチンカルシウム (JP18);
Rosuvastatin calcium (JP18/USP);
ZD 4522
商品名   
  後発品
米国の商品 
  後発品
ROSUVASTATIN (A-S Medication Solutions), ROSUVASTATIN (Accord Healthcare), ROSUVASTATIN (Amneal Pharmaceuticals NY LLC), ROSUVASTATIN (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN (AvPAK), ROSUVASTATIN (Bryant Ranch Prepack), ROSUVASTATIN (Bryant Ranch Prepack), ROSUVASTATIN (Camber Pharmaceuticals), ROSUVASTATIN (DIRECT RX), ROSUVASTATIN (Direct_Rx), ROSUVASTATIN (Golden State Medical Supply), ROSUVASTATIN (NuCare Pharmaceuticals), ROSUVASTATIN (NuCare Pharmaceuticals), ROSUVASTATIN (NuCare Pharmaceuticals), ROSUVASTATIN (Preferred Pharmaceuticals), ROSUVASTATIN (Preferred Pharmaceuticals), ROSUVASTATIN (Proficient Rx LP), ROSUVASTATIN (Quality Care Products), ROSUVASTATIN (REMEDYREPACK), ROSUVASTATIN (ScieGen Pharmaceuticals), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (A-S Medication Solutions), ROSUVASTATIN CALCIUM (American Health Packaging), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Aphena Pharma Solutions - Tennessee), ROSUVASTATIN CALCIUM (Ascend Laboratories), ROSUVASTATIN CALCIUM (Aurobindo Pharma Limited), ROSUVASTATIN CALCIUM (Biocon Pharma), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Bryant Ranch Prepack), ROSUVASTATIN CALCIUM (Cadila Pharmaceuticals Limited), ROSUVASTATIN CALCIUM (Cardinal Health 107), ROSUVASTATIN CALCIUM (Denton Pharma), ROSUVASTATIN CALCIUM (EMC PHARMA), ROSUVASTATIN CALCIUM (Glenmark Pharmaceutials), ROSUVASTATIN CALCIUM (Golden State Medical Supply), ROSUVASTATIN CALCIUM (MSN LABORATORIES PRIVATE LIMITED), ROSUVASTATIN CALCIUM (Major Pharmaceuticals), ROSUVASTATIN CALCIUM (NorthStar RxLLC), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Northwind Pharmaceuticals), ROSUVASTATIN CALCIUM (Novadoz Pharmaceuticals LLC), ROSUVASTATIN CALCIUM (NuCare Pharmaceuticals), ROSUVASTATIN CALCIUM (NuCare Pharmaceuticals), ROSUVASTATIN CALCIUM (NuCare Pharmaceuticals), ROSUVASTATIN CALCIUM (NuCare Pharmaceuticals), ROSUVASTATIN CALCIUM (NuCare Pharmaceuticals), ROSUVASTATIN CALCIUM (PURACAP LABORATORIES LLC DBA BLU PHARMACEUTICALS), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals Inc.,), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Preferred Pharmaceuticals), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (Proficient Rx LP), ROSUVASTATIN CALCIUM (QUALLENT), ROSUVASTATIN CALCIUM (Quality Care Products), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (REMEDYREPACK), ROSUVASTATIN CALCIUM (Rising Pharma Holdings), ROSUVASTATIN CALCIUM (Shandong New Time Pharmaceutical), ROSUVASTATIN CALCIUM (Solco Healthcare LLC), ROSUVASTATIN CALCIUM (Sun Pharmaceutical Industries), ROSUVASTATIN CALCIUM (TORRENT PHARMACEUTICALS LIMITED), ROSUVASTATIN CALCIUM (Torrent Pharmaceuticals Limited), ROSUVASTATIN CALCIUM (Tris Pharma), ROSUVASTATIN CALCIUM (UMEDICA LABORATORIES PRIVATE LIMITED), ROSUVASTATIN CALCIUM (Westminster Pharmaceuticals)
組成式   
(C22H27FN3O6S)2. Ca
質量    
1000.2835
分子量   
1001.1374
構造式   
クラス   
脂質降下薬
 DG01946  脂質低下薬
  DG01660  HMG-CoA還元酵素阻害薬
トランスポーター基質薬
 DG01913  ABCG2基質薬
 DG02856  SLCO1B1基質薬
コード   
薬効分類: 2189
ATCコード: C10AA07
化学構造グループ: DG00357
商品 (DG00357): D01915<JP/US>
商品 (mixture): D11520<JP>
効能    
脂質異常症治療薬, HMG-CoA還元酵素阻害薬
  疾患
高コレステロール血症 [DS:H01635]
家族性高コレステロール血症 [DS:H00155]
ターゲット 
HMGCR [HSA:3156] [KO:K00021]
  パスウェイ
hsa00900  テルペノイド骨格の生合成
代謝    
Transporter: SLCO1B1 [HSA:10599], ABCG2 [HSA:9429]
相互作用  

構造マップ 
map07024  HMG-CoA 還元酵素阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  21  循環器官用薬
   218  高脂血症用剤
    2189  その他の高脂血症用剤
     D01915  ロスバスタチンカルシウム (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 C 循環器系
  C10 脂質修飾剤
   C10A 脂質修飾剤、単剤
    C10AA HMG-CoA 還元酵素阻害薬
     C10AA07 ロスバスタチン
      D01915  ロスバスタチンカルシウム (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 心血管治療薬
  脂質異常症治療薬, ヒドロキシメチルグルタリルコエンザイムA還元酵素阻害薬
   ロスバスタチン
    D01915  ロスバスタチンカルシウム (JP18)
医薬品グループ [BR:jp08330]
 脂質降下薬
  DG01946  脂質低下薬
   DG01660  HMG-CoA還元酵素阻害薬
    DG00357  ロスバスタチン
     D01915  ロスバスタチンカルシウム
 トランスポーター基質薬
  DG01913  ABCG2基質薬
   DG00357  ロスバスタチン
    D01915  ロスバスタチンカルシウム
  DG02856  SLCO1B1基質薬
   DG00357  ロスバスタチン
    D01915  ロスバスタチンカルシウム
医薬品クラス [BR:jp08332]
 心血管系用薬
  DG01946  脂質低下薬 [商品一覧]
   D01915  ロスバスタチンカルシウム
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  オキシドレダクターゼ (EC1)
   デヒドロゲナーゼ
    HMGCR
     D01915  ロスバスタチンカルシウム (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D01915  ロスバスタチンカルシウム
  D01915  ロスバスタチンカルシウム錠
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D01915
日本・米国・欧州の新薬 [jp08328.html]
 日米欧での承認状況
  D01915
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物トランスポーター
  D01915
ゲノムバイオマーカー [jp08341.html]
 医薬品応答に影響を与える多型と変異
  D01915
医薬品グループ [BR:jp08330]
 脂質降下薬
  DG01946  脂質低下薬
   DG01660  HMG-CoA還元酵素阻害薬
    DG00357  ロスバスタチン
 トランスポーター基質薬
  DG01913  ABCG2基質薬
   DG00357  ロスバスタチン
  DG02856  SLCO1B1基質薬
   DG00357  ロスバスタチン
リンク   
CAS: 147098-20-2
PubChem: 7848977
LigandBox: D01915
LinkDB    

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