Danio rerio (zebrafish): 100330031
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Entry
100330031 CDS
T01004
Symbol
itchb
Name
(RefSeq) itchy E3 ubiquitin protein ligase b
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04120
Ubiquitin mediated proteolysis
dre04144
Endocytosis
dre04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100330031 (itchb)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100330031 (itchb)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100330031 (itchb)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dre04131
]
100330031 (itchb)
04121 Ubiquitin system [BR:
dre04121
]
100330031 (itchb)
Enzymes [BR:
dre01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100330031 (itchb)
Membrane trafficking [BR:
dre04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100330031 (itchb)
Ubiquitin system [BR:
dre04121
]
Ubiquitin ligases (E3)
HECT type E3
100330031 (itchb)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100330031
NCBI-ProteinID:
NP_001289155
ZFIN:
ZDB-GENE-131024-2
Ensembl:
ENSDARG00000099199
UniProt:
U6C7R6
LinkDB
All DBs
Position
23:complement(43531956..43595780)
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AA seq
867 aa
AA seq
DB search
MACSVAKAAPANGFPMKAQLQIMVISAKLKENKKNWFGPSPYVEVCVDGQSKKTEKCNNT
HSPKWKQSFVVIVTPFSKLIFRVWSHQTLKSDLLLGVATLDISETLKSHDMKICEVVQTL
QLCDRDQSDSIGDLSVCLDGLQVDPEMFQSAEASNQNTLNGESELNEDSGRSRDPSPSVS
EGQDRPAAPNGRVNGLDSPSVSARSSRAQRPPRPSRPPPPTPRRPTSSPASSTGSFPDGS
DSSRSDTPVRNPTGGGASDSSPAPTVEQPGRTALSVGPTPSRIPSMVNAGPLPPGWEQRV
DQNGRLYFVDHVEKRTTWERPEPLPSGWERRVDPMGRVYFVDHITRTTTWQRPTMETVRN
YEQWQHQRSQLQGAMQQFNQRFIIGLQDQASATQNKEFDPLGPLPHGWEKRTDSNGRVYF
VHHPTRSTQWEDPRTQGLLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSSL
ENGPQITYVRDFKAKVQYFRFWCQQLSMPQHIKINVSRKTLFEDSFQQIMSFSAQDLRRR
LWIIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLK
YFKFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPLTLKDLESIDPEFYNSLIWIKDNNI
EECGLEMFFSVDKEILGEVSTHELKPDGGNIQVTEENKEEYIRLVAEWRLSRGVEEQTQA
FFEGFNEVLPQQYLQYFDAKELEVMLCGMQEIDLNDWQRNTIYRHYTSSSKQIMWFWQFI
KEMDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLD
LPPYRSYEQLKEKLMFAIEETEGFGQE
NT seq
2604 nt
NT seq
+upstream
nt +downstream
nt
atggcctgcagtgtcgctaaagctgctcctgctaatggcttcccaatgaaggctcagctg
cagatcatggtgatttctgccaaactcaaggaaaacaagaagaactggttcggtccgagt
ccgtatgtggaggtgtgtgtagatggccagtcgaagaagacagagaaatgcaacaacaca
cactcgcccaagtggaagcagtcgttcgtagtgatcgtgactccattcagcaagctgatc
ttccgtgtttggagccaccagacgctcaaatcagaccttctgctgggcgtggccacactc
gacatcagcgagacgctcaagtcacatgacatgaaaatctgtgaggtggtgcagacgcta
caactgtgcgacagggatcagtctgacagcatcggggatctgtccgtgtgtctggacggc
ctgcaggtggatcctgaaatgttccagtcagctgaggccagcaaccagaatactttaaat
ggggaatctgagctcaatgaagactcgggccgaagcagagatccatctccttcagtgtca
gagggtcaggatcgtccggcggctcctaacgggcgagtgaatggcttggattctccttca
gtttctgccagaagctctcgagctcagagacctccgcggccctcacgccctcctccaccc
acccctcgcagacccacatcttctccagcttcctctaccggctcatttccagacggcagc
gattcgtctcgttcagacactccagttcggaatcccacagggggaggagcctcagattct
agccccgcccccacagtggagcagcctggtaggacggcccttagtgtaggccccaccccc
agcaggatccccagcatggtgaacgctggaccgctgccacccggttgggagcagcgtgtg
gatcagaatggccgtctgtactttgttgatcatgtggagaagaggacgacatgggagaga
ccagagccactgccgtcaggctgggagcggcgcgtggacccgatgggtcgggtgtatttc
gtggatcacatcaccagaaccaccacatggcagcggcccaccatggagacggtgcgcaac
tatgagcagtggcagcaccagcgcagtcagctgcagggggcaatgcagcagttcaaccag
aggttcatcatcgggctccaggatcaggcttcagccacccagaataaggagtttgatccg
ctgggtccactgccgcacggctgggagaagagaacagactccaatggcagagtttatttt
gttcatcacccgaccagatccacacagtgggaggatccgcgaactcaaggtctgcttaat
gagaagcctctgcctgaaggatgggagatgaggttcacggtcgatggcatcccttacttt
gtagatcacaaccgcagaaccactacttatatcgacccgcgcactggaaaatcctccctt
gagaacggtcctcagatcacatacgtacgagacttcaaagccaaagttcagtacttcaga
ttctggtgtcagcaattatcgatgccgcagcacataaagatcaacgtcagccgcaaaact
ctctttgaggactccttccagcagatcatgagttttagtgctcaggatctgcggcgcagg
ctctggatcatctttcctggagaagaaggactggattatggaggagtggccagagagtgg
tttttcctgctgtcccacgaggtcctgaacccgatgtactgcctgtttgaatacgccggg
aaagacaactactgtctgcagataaaccccgcctcctacatcaaccccgaccacctcaaa
tacttcaagttcattggtcgcttcatcgccatggctttgtttcatgggaagttcatcgac
acaggcttttctctgccgttctacaagcgcatcctgaacaagccgctgactctcaaagac
ctggagtccatcgacccggagttttacaactcgctcatctggatcaaggataataacatc
gaggagtgcggcctggagatgtttttctcggtggataaggagattctgggtgaagtgtcg
actcacgagctgaagccggacggaggaaacattcaggtcaccgaggagaataaggaggag
tatattaggctggtggcagagtggcgtctgtctcgcggtgtggaggaacaaactcaagct
ttctttgagggattcaacgaggttcttccacagcagtacctgcagtatttcgatgccaaa
gaactggaggtgatgttgtgtgggatgcaggaaatcgacctgaacgactggcagaggaac
accatttacagacattacacctcctccagtaaacagatcatgtggttctggcagttcatt
aaggagatggacaatgaaaagcgtatgagactcctgcagttcgtcacaggcacctgccgt
ctgcctgtcggaggattcgcagacctcatggggagcaatggaccacagaagttctgcatc
gagaaggtcggcaaagagaactggcttcctcggagccacacatgcttcaaccgtctggat
ctccctccgtaccgaagctacgagcagctgaaggagaagctgatgttcgccatcgaggag
accgagggcttcggtcaggagtga
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