Danio rerio (zebrafish): 557983
Help
Entry
557983 CDS
T01004
Symbol
arhgef1
Name
(RefSeq) rho guanine nucleotide exchange factor 1
KO
K12330
Rho guanine nucleotide exchange factor 1
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04270
Vascular smooth muscle contraction
dre04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
557983 (arhgef1)
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
557983 (arhgef1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dre04131
]
557983 (arhgef1)
Membrane trafficking [BR:
dre04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
557983 (arhgef1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PH_13
PH
DUF7744
Motif
Other DBs
NCBI-GeneID:
557983
NCBI-ProteinID:
NP_001038313
ZFIN:
ZDB-GENE-060616-136
Ensembl:
ENSDARG00000055837
UniProt:
F1Q4Y0
LinkDB
All DBs
Position
16:complement(29265737..29355401)
Genome browser
AA seq
1005 aa
AA seq
DB search
MDYEDAHNGRGLSGAQGLNPVMNIIGAEDEDFENDEQPMVDDQCIHFNSIELLKSRPTHL
LVFLHHVMLQFDCAPVLCYLHADLMKNLNTKDTKKHFGEFYNTFLEKGAILKVSVPSNIA
PEIDRLRPELINEEQQKRYANEIQFAQSPEILRQLEDFRQKRMMGMTPNERELNDVESHR
PTDRIPMDMKEKAVAESLLEKMVEANPSIVPDKDKSNSIFGAVAYYMKYLGVKTRAFDNK
KSKSGWRPSVPSMLKPWSVNKQIKPVKPPGIGYDGKQSRLDFEAKQNKQPPHRVSVSDSV
TPPGRKTGITVSGSTHGSESSEELPISVSVTPSPDFQTDTVGIINNRTDPKPASEGGEVS
PVSTGGTVSICEPLAVIDVPPEDIQDSGSVEGDKTPEIALLTPTFVPAPQQEEIEPRLLE
LEQDPLNWRELASSESLHKLSKKEAKRQEVINELFVTEQAHVRMLSVLQTVFSRPLEKQE
YMTANEVATIFSSLDDIIEMHYVFYENLKKLREEDEYIVKTISTPLLNRFSGSEGEWFQK
LTARFCSYQSWALEQIKSRQKKDPRFNAFILEAESKPQCRRLQLKDIIPIEMQRLTKYPL
LLENIAKNTEDATEKEKINQAAESCRKILNHVNEEVKQMENLLILKDYQRRLDTSGLKPS
NELYSEYKTIDLTNRTMLFEGPLTWRVTKEKAIDVHCVLLSDLLVLFQKQDDKMLLKCQS
KSNIAVQEGKQMLSPIIKLESVFLREVATDPKALYVIFTWDSGAQIYELVAQSVGERKNW
TEAIKSAVDELKKASKSNTKLERNSRAGSVPNNIAVPLYGPAHPPLSPTENGGELLKNRV
GRFSEKIRESDPPLIDYLAANGFDLLTHSHTPPEKSATVALDEVMCLKRLLVGSISLSDD
AQTLGENGGMAPESQDADGTQLSVEESSTEAGPEVEEHEEDVENKGEEEKGISAPLVLSE
ERMEEVQMRLQALEEQLKRLRLVEEDHYKLQEALAKYTLQGGHYN
NT seq
3018 nt
NT seq
+upstream
nt +downstream
nt
atggattacgaagacgcccataatgggcgcgggctgtcaggtgctcagggtttaaatcca
gtcatgaacataatcggagcagaggatgaagactttgagaatgatgagcagcctatggtg
gacgatcagtgcattcactttaacagtattgagctgttgaagtccaggcccacccacctg
ctggtgttccttcatcatgtcatgctacagtttgactgtgctcctgtgctatgctacctt
catgctgacctcatgaagaacctcaataccaaagacaccaagaagcactttggggaattc
tacaacactttcctggagaaaggagcgattctcaaagtatctgtaccaagtaacatcgcc
cctgaaatagatcgcttgcgtccagaactgatcaatgaagagcagcaaaaacgttacgct
aatgaaatacagtttgcgcagagtccagagatactgcgacagctggaagacttcaggcaa
aagaggatgatgggaatgacacctaatgagcgggaattaaatgatgtggaatcccatcga
cccactgatcgcatccctatggacatgaaggagaaggctgtcgctgaatccctgctggaa
aagatggttgaggccaacccctcaattgttcctgacaaggacaaaagtaactccatcttt
ggagcagtggcttattatatgaagtatcttggagtcaagaccagagcttttgacaacaag
aagtccaagtcaggatggcggccctcggttccatctatgctgaagccatggtcagtcaac
aagcagattaaaccagtcaaaccgcctggaatcggctatgacggtaagcaaagtagattg
gactttgaagcaaagcaaaacaaacaacctcctcatcgagtgtctgttagtgatagtgtc
acccctccagggcgaaaaactggtattaccgtgtcagggagcactcatgggtcagagagc
agtgaagagttacccatcagtgtgagtgtgactcccagccctgactttcaaactgataca
gtaggtatcatcaacaatcgcacagaccccaaaccagcctctgagggtggagaagtgtct
ccagtcagcactggtgggactgtgtccatctgtgaacctctcgctgtcattgatgtccct
ccagaagacattcaggacagcggcagcgtggaaggtgacaaaacaccggaaatcgctctc
ctcactcccacttttgtcccggcccctcagcaagaagagatagagccccgtctcctggag
ctcgagcaggacccactcaactggagagaacttgcttccagtgaaagcctgcataagctg
agcaagaaggaagccaaaagacaagaagtcataaatgagctgtttgtgacagaacaagca
cacgtccgtatgctgagtgtattgcagacagtgttttctcgtccacttgagaagcaagag
tatatgactgcaaatgaggtggccaccatcttctccagcctggatgacatcatagagatg
cactatgttttctatgagaacctgaagaaactgcgtgaagaagatgaatacattgtcaaa
actatcagcacaccacttctcaacagattcagtggatctgaaggagaatggtttcaaaag
ctcacagcacgcttctgtagctaccagtcctgggctctggagcagatcaagagcaggcag
aagaaggacccccgattcaatgcttttatactggaagcagagagtaagccacagtgtcgg
aggctacagctaaaggatatcatacccatagagatgcagagactaacaaaataccctctt
ctgctggaaaacattgctaagaacacagaggatgcaacagaaaaagagaaaattaaccaa
gcagcagaatcctgccgtaagatcctcaaccatgtcaatgaagaagtcaaacaaatggag
aacctgctgattttgaaagactaccagcgtcgactggatacctcaggactgaaacccagc
aatgaactctacagtgagtacaagaccattgatctgaccaaccgaacgatgctgtttgaa
ggacctctgacatggagggtgaccaaagagaaagcaatcgatgtgcactgtgtgttgctg
tcagacctgctggtcttgtttcagaagcaggatgataagatgcttttgaagtgtcagagc
aaaagcaacatcgccgttcaggaaggcaagcagatgctgagtccaatcatcaagctggag
tctgttttcctcagagaggtggccactgacccgaaggccctgtatgttatcttcacctgg
gacagtggagcacagatctatgaactggtggctcagtctgtcggggagaggaaaaactgg
acagaggcgattaagtctgcggttgatgagctgaagaaggcatcaaagagcaacaccaaa
ctggaaaggaatagcagggctggcagtgtgccaaacaacattgctgtacctctatatggc
ccagctcatcctcctcttagccccactgaaaatggaggtgaactgctgaaaaatcgcgtc
gggcgatttagtgagaagattcgagaaagtgatcctccactcatcgactatctagcagcc
aacggctttgacctgctcacccacagccacacacctccggagaaatctgctactgttgct
ttggatgaagtcatgtgtttgaagaggctattggttgggagtattagcctgtcagatgat
gctcagactcttggggaaaacggtgggatggcacctgaaagtcaggatgcagatggaact
caactgtcagtggaggaatcgagcacagaagcaggtcctgaagtagaagagcatgaggaa
gatgtagagaataaaggagaagaggagaaaggtatcagtgctcctctcgtgctgtctgag
gagcgcatggaggaggtgcagatgagactgcaggctctggaggagcagctgaagagattg
aggttggttgaggaggaccattataaattacaagaagctcttgctaaatacacacttcag
gggggccattacaattga
Danio rerio (zebrafish): 562455
Help
Entry
562455 CDS
T01004
Symbol
arhgef12a
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04270
Vascular smooth muscle contraction
dre04625
C-type lectin receptor signaling pathway
dre04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
562455 (arhgef12a)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
562455 (arhgef12a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
562455 (arhgef12a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dre04131
]
562455 (arhgef12a)
Membrane trafficking [BR:
dre04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
562455 (arhgef12a)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
PH
Motif
Other DBs
NCBI-GeneID:
562455
NCBI-ProteinID:
XP_009290006
ZFIN:
ZDB-GENE-121017-3
Ensembl:
ENSDARG00000030532
UniProt:
E7FDV8
LinkDB
All DBs
Position
15:24913250..25004369
Genome browser
AA seq
1357 aa
AA seq
DB search
MSDTRSTVSDRTSSFLSRDHPPDKRPKSDKLPGTPTHEFDPTDVLVQKSGCVVADRRPES
CGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKQDGAAMRAGVQTGDRIIKVNGTLVTQS
NHVEVVKLIKSGSYVALTVLGRPPGLPQIPLPEVDVGLESPDVFGDPFITSPNSYNAAER
TSSPLVSWEENSALHNQRMDSRRTGLKDQQDTQESPCLRNSEDGSWAEEDQYKRDFSPEA
FWSGNSVPSVHRRFYPASPESQRDSNCSSPKSTPRDSFNSCPSPEVDYGSDLDSRFPSTV
GSPRLVSEIIAAEDDDFDSEQEQVNGQCSCFQSIQLLKTRPAHLAAFLHHVISQFDPAPL
LCYLYADLYKQTNSKETRRIFTDFLTFFIDRGANLKVTVPESISSELERRRPELIPEELH
RQYIQTMQETLFPDVQRNLEDFRQKRSMGLTLADTELSRLDSEQLAVDRERACAESILSK
IDDVLLTSQPTEEEKCSTIQYVIFMYMKHLGVRAKEQRNLESKRVRINFLPSKLRKSKTE
KDGEEKLKKSRFPIRVPPRWPGRLDSVPSGRVGDSIKQRPQKQMSQPALGGSELIDAGRL
RGSQSSEGSDLLHSPGLITSSPFSAPYSSPSDPSGRDSEFNMSPSAVVPRLSDGLQSGDP
LDSIYPPCDYIPYNVDQLDEDRDGDRPPDVGTPKPSRRFEDLQSEDDQGSDVYSDVDPPN
WQQLVGRDVLAGLTPHEIKRQEVINELFYTERAHVRMLKVLDKVFYQKLNRDNILPPADI
KYIFTNLEEIIQLHVRIVDQMTAICKKNETSVIDHIGDELLSWFSSGEEEKIKQAVGTFC
SNQPFALELIKSRQKKDQRFSSFMQEAESNRLCRRLQLKDIIPAEMQRFTKYPLLMDNIA
KYTDESEEKDKVRRAAECCRQILNHVNQSVKESENKQRLEDYQRRLDLSSLKQSENPMIS
EFKNLDLTKRKMVHEGPLSWKINKDKTIELYTLLLEDILVLLQKQDERLILRCHSKNLAG
TAETKHIFSPIIKLSTVLVRSVATDNRSFFVISMSKNGAQIYELMAQTVSEQRMWQRQIT
QRAEVMNTKPHSVIPLPQHDGDRDGVELSKFSKGSDRISTGSIQSAEKDGEFSPSAALRD
CVPDTNPGEEDQVARAGRDASYQDSELLNGRETDSLSCSSKADEALKTLAALKQVLLTQL
MAQDEGERLGRSAGSRLLRTTSLRTPVEHNSNRTPSRAQDYTSGDTGFYECPEDYAAYLV
LEGFGGSGESSTDDDFQVGRKEPGLAHSCAADSGISLKFSSPSSGSTSRLSRQVLSHLRC
LQANLNHLKEMETKYYNLLRQRPVGSAAEADESREKK
NT seq
4074 nt
NT seq
+upstream
nt +downstream
nt
atgagcgacacacggtctacagtcagtgacagaaccagtagctttctcagcagagaccac
cctcccgacaagaggcccaaaagtgataagctgcccggtaccccaacacacgagtttgac
ccaacagacgtgctggtgcagaagagtggatgtgtagtggctgacaggagacctgagtct
tgtgggctagtgcagagatgcgtgatcattcagaaagatgagaacggctttgggctgacc
gtcagtggggacaaccctgttttcgtgcagctcgtcaaacaggatggcgctgccatgcga
gcaggtgttcagacgggggacaggatcattaaggtgaacgggaccttggtaacgcaatca
aaccatgttgaggtggtgaagttaatcaaatccggctcttatgtagctctcacagtatta
ggccgaccgcccgggttgccccagatccccctccctgaggtggacgtgggtctcgagtca
ccggatgttttcggggacccttttattacatctcccaactcttacaatgcagcagaacgc
acctcctctcctcttgtatcatgggaagagaacagtgctctacacaaccaaagaatggac
agcagaaggactggtttaaaggatcaacaggacacgcaggagagtccgtgtctcaggaac
agtgaagatggctcatgggcggaagaggatcaatataagagagatttcagcccagaggct
ttttggagcggaaattcagtgccatctgtccaccggcgcttctacccagcttctccagag
agtcagcgggactctaactgttccagtccgaaaagtacccccagagacagcttcaactcc
tgcccttctcctgaagttgactacggctctgacctggattctcgattcccatccaccgta
gggagcccacgtttggtttctgagatcattgctgctgaagatgatgactttgactctgag
caggagcaggttaatggccagtgcagctgcttccagagcatccagctgctcaagactcga
cctgctcatcttgctgcttttctgcatcatgtgatctctcagtttgaccctgcacctctg
ctctgctatctgtatgctgacctctacaaacagaccaactccaaagaaactcggcgcatc
ttcacggacttcttgacgttcttcatagaccggggggcaaatttgaaagtcactgtgcct
gaatccatctcgtctgaactcgagcggaggagaccagaattgattcctgaggaattacac
aggcagtacatacagacaatgcaggaaactctctttcctgatgtacagaggaacctggaa
gacttcaggcagaagcgtagtatgggcttgaccctggcggatacagagctgtctcgtctg
gactctgaacagctggctgtagacagagagagagcctgtgctgaaagcatcctctcaaag
atagatgacgttctgttgacttcacaacccacagaagaggagaaatgctccactatacag
tatgtgatcttcatgtacatgaagcatctgggagttcgggcgaaagaacaacgaaacctg
gaatccaaacgagttcgaattaatttccttccttccaaactaaggaaaagcaaaacagaa
aaggatggggaggagaaactaaaaaagtctcgcttccccatccgggtgcccccgcggtgg
cccggtcgcctcgattcagtaccatctggtagggtcggggacagcatcaagcaaagacct
cagaagcagatgtctcagccggcactgggcggctcagagctgatcgatgccggacgtctg
aggggcagtcagtcaagtgagggctcagacctgctccacagcccaggactgatcacctct
tccccctttagtgccccctacagctcaccgtcagacccctctggcagggactctgagttc
aatatgagcccgtctgcggtggttcctcggctcagtgatgggctgcagtctggagatcca
ctggacagcatttacccaccctgtgactacatcccatacaacgtggaccagctggatgaa
gacagagatggagacagacctcctgatgtgggcacacctaaaccgagcagaaggtttgag
gatctgcagagtgaggatgatcaggggagtgatgtttactctgatgtagatcctccaaac
tggcagcagctggtcgggcgtgatgttttagcaggcctgacgccccacgagatcaagaga
caagaagtcattaatgagctgttctacacggagcgagctcacgtacgcatgttgaaggtc
ctagacaaggtcttctaccagaaactcaaccgagacaacatactgccccctgctgacatc
aagtacatattcaccaacctggaggaaatcatccaactccacgtgagaatagtggatcaa
atgacagcaatttgcaagaagaacgagacgtctgtaatcgaccacataggagacgagttg
ttgtcttggttcagcagtggagaggaggagaagatcaagcaagcagtgggcactttctgc
agtaaccagcccttcgccctggagctcatcaaatcccgacagaagaaggaccaacgtttc
tcctccttcatgcaggaggctgaaagcaatcgactgtgtcggcgtctacagctaaaggac
atcatccctgcagagatgcagaggttcaccaaatacccattattaatggacaacattgcc
aaatacacagatgagtcagaggaaaaagacaaagtgagacgagcagcagaatgctgtcga
cagattctcaaccacgtcaatcagtctgtgaaggagtccgagaataaacagagactggaa
gactaccagagacggctggacctctcttccctcaagcagagcgagaacccaatgatctca
gagttcaagaacctggatctcactaaacgaaagatggtccacgagggtcctctctcctgg
aagataaataaagacaaaacaattgagttgtatacgttactcctggaagacatactggtg
ctgctgcagaagcaggacgagcgtctcattctcaggtgtcacagtaagaacctggcagga
acagctgaaaccaaacacatcttcagccctatcatcaagctcagcactgtgctggtgcgc
tctgtggccacagataatagatcattctttgtgatctccatgtccaaaaacggagctcag
atttatgagctgatggcccagacggtgtctgagcagaggatgtggcaacggcagatcact
cagagggcagaggttatgaacaccaaacctcacagtgtcattcctttgcctcaacacgat
ggcgacagagacggtgtggagttaagcaagttcagcaaaggctctgatcggatctccaca
ggaagcatccagtccgcagagaaagacggtgaattttcgccctcagcagccctgcgggac
tgtgtgcccgataccaaccctggggaagaggaccaggtcgcgagagctggcagagacgct
tcctatcaggactctgaacttttgaacggcagggaaacagactctctatcttgttcatct
aaagctgacgaggccctgaaaacattggcagcgctaaagcaggtgctgctgactcagctg
atggctcaggatgagggtgagcgattgggccgatcggccggcagtcgtctgctcaggacc
acctctttacgcacaccagtggagcacaactccaaccgcacccctagtcgagctcaggac
tacacctctggcgacacaggcttctatgagtgcccggaggattacgcagcgtacctggtt
ctggagggcttcggtggctcgggcgagagcagcactgatgatgattttcaggttgggaga
aaggagcctggtttggcccacagctgcgctgctgactctgggatcagcctgaagttctcc
tcgccctcctctggcagcacgtcccgtctcagcagacaggtgctctcacacctgcgctgc
ctgcaggccaacctcaaccacctcaaggagatggaaactaagtattataatctacttcgc
caaaggcctgtcggatcagcagcagaagcagacgagagcagagagaagaaataa
Danio rerio (zebrafish): 565268
Help
Entry
565268 CDS
T01004
Symbol
arhgef11
Name
(RefSeq) rho guanine nucleotide exchange factor 11
KO
K12331
Rho guanine nucleotide exchange factor 11
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04270
Vascular smooth muscle contraction
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09150 Organismal Systems
09153 Circulatory system
04270 Vascular smooth muscle contraction
565268 (arhgef11)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dre04131
]
565268 (arhgef11)
Membrane trafficking [BR:
dre04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
565268 (arhgef11)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
RhoGEF
PH_16
PDZ
PDZ_6
PDZ_2
RGS
Pept_S41_N_bact
Motif
Other DBs
NCBI-GeneID:
565268
NCBI-ProteinID:
NP_001027010
ZFIN:
ZDB-GENE-070604-1
UniProt:
Q49U75
LinkDB
All DBs
Position
7:complement(5113686..5220567)
Genome browser
AA seq
1417 aa
AA seq
DB search
MNVRHPTSTLDRLSSLTLGDSERRSSPGQQRETLPDLSSDNTGTGLVQRCVVVQRDNLGF
GFTVCGERIKLVQNVRPGGAAVKAGVQEGDRIIKVNGSMVSSMSHQEVVKMIKSGTYVAL
TLQGPPPSVASTPLQPLPSDLLSNHRTAPGEAPPLPQTPPTGSSTPTQRITGPKPLQDPE
VQKHATEILRKMLEQEEAELQNLLEEQSRNPSVSLEERIERAKRRASQVRVKIQQDVDGT
RSDAVANYLTAGEGRLSIDSSEGDVEVCESPFSSPSSFLRNPLIHRQTSDTHTSDSGKMQ
IIGPEEEEEDDGYTINEMDGPFQDIELLKSRPAHMTVFMRYVFGQLLDPNPLLFYLSVEA
YLGSSPKDARSLAPQICSHFLDHDAPLKIKVREEFLTDIENRLHAQEDIRGPLSELQQQV
LPDIQDQLQDYRNKQTMGLGSLFGESDLQQLDGDPVKEKQVVDKQIVALWEILSKHEEDR
SSPLASAVHLYLRHSGIKLRDSKVFPGLMSEKEKWLPFFPKAKKLSSAKRERDGEDKKRN
PILKYIGKPRSTSQSTFHVPLSPTEVRPGSVRNIIQQFESNSDSLEDGELEGQRLSGSFG
EDSMESPTISVRLARSESLKAQGEGRRRGGGTGAEFVPRSRSDVDMEDCEEREGPGLRPL
HHSASSSASSSSARSLENPTPPYTPRSQRRIVEVPVSLLPDAPALDEDVIDSHNWQDTVE
PHILASLTSREIDRQAVIYELFTTEVSHLRTLRVLDQVFYQKMQSVLSPEELSCIFLNLR
QVYELHASLCESMKKCRESVIVQGIGDIMLARFEGEAGDQFEEQVSHLCSQQSPALELIK
NKQRKDPRFAHLIQECEASPHCRRLQLKDLLVSEMQRLTKYPLLLDNIIKYTETSSPDLP
LLRRAQACCRGILQEVNEDVRETEHRHLLSQYQRRLDATPLERLANPVAAQFRNLDLTTK
RMVHEGPLTWRVGKDKAIEIQALLLSDLLLLLQRGPDDRLILRCPSRSLGGVTDLKTPFC
PVVCLDSCLVRPVATDNKALYVISTSERQIYELVAGTLLEKNTWKDQLEKTISAAAQGGS
TKPNTPRFRSPGAGVRLSADQSEGSESRMYPDREDEMVLSPVVTPADAAEECPDEDPDPG
QKNKAGVAESALQDVETLRQLIFRDLEDGWSQDSDDTPTNETANERSPFTDRPGNESSDP
APSESSSQWEEEPVEAPPLEVLQPAVQVVRKAVGVGCSLPDDITDDVTASQSSEDGGNLF
YLVMSTDQVVSDESTTDELKDLHHSVFSSSFINEEEEQDTPCLSPTDQSLIESQGHRPGL
SQSQSSVQRHVIKNVDEIFNTMEELMKKLQHLRDIEADHHKLLKKLRKPLPVDKMSSDGV
HKSPTAARLSSLDRGAGDGKEGVSTEPAQPQIQSTGF
NT seq
4254 nt
NT seq
+upstream
nt +downstream
nt
atgaatgtccgacacccgacctccacgctggacaggttgagcagtctgacattaggagac
tctgagcgcaggtcttctcctggccagcagagggaaacactgcctgatctctcttcagac
aacaccggaacgggtttggtccaaagatgcgtggtcgtgcagagggacaatctggggttt
ggcttcacggtgtgcggagagagaatcaaactggtgcagaacgtccggccgggtggagca
gcggtgaaggctggagttcaggaaggagaccgaatcattaaggtcaatggctccatggtt
tcctccatgtcccatcaggaagtggtgaagatgatcaaatctgggacgtatgtagcactg
actcttcaaggcccgcctccttcagtcgcatccaccccactgcagccccttccttctgac
ctcctgtccaatcacaggacagcaccgggtgaagccccacctcttccacagactccaccc
acaggaagcagcaccccaactcagaggatcacaggacccaaacctttacaggaccctgag
gtgcagaaacacgccacagaaatcctccgaaagatgctggagcaggaggaggccgagctg
cagaatcttctggaggagcagtccagaaacccctcagtttcattagaggagcggatcgaa
cgtgccaaacgaagagccagtcaggtcagagtgaagatccagcaggacgtggacggcact
cgatcagatgcagtcgctaactatctcacagcaggagaaggccgactgtccatagactcc
agtgaaggagacgtggaggtgtgtgagagccccttctcctctccatcatccttcctcagg
aaccccctgacccaccggcggacctccgacacgcacacctctgattcgggaaagatgcag
atcattggaccagaggaagaagaggaggatgatgggtacacgatcaatgagatggacggg
ccgtttcaggacatcgagctgctgaagagtcgtccggcacacatgacggtgttcatgaga
tacgtcttcggtcagctgctggatccaaacccactgctgttttacctgtcggtggaggcg
tatctgggttcgagcccgaaagacgcccggtcactcgccccgcagatctgctcacacttc
ctggaccatgatgctcctctgaagatcaaagtgcgtgaggagtttctgactgatatcgag
aatcgtcttcatgctcaggaggacattcgaggacctctttctgaactacagcagcaggtg
cttccagatatccaggatcagctgcaggactacaggaataagcagacgatgggtctgggc
tctctttttggagagtctgacctgcagcagctggatggagaccctgtcaaagagaagcag
gtggtggacaaacagattgtggccctctgggaaatactctcaaaacatgaggaggacaga
agttctcctttagcatctgccgttcatctatatctccgacattcgggaattaaactcaga
gactccaaagtgtttcccggcttgatgtccgagaaggaaaagtggcttcctttctttccc
aaagccaaaaagctgagcagcgcaaaacgagagagagatggagaggacaagaagagaaac
cccatactgaagtacatcggcaaacccaggagcacatcgcagtccacgttccatgtcccc
ctgtcccccactgaagttcgtccgggcagcgtcaggaacatcattcagcagtttgagagt
aattccgactctctggaggacggagagctggaggggcagagattgtccggcagcttcggg
gaggacagtatggagagtccgaccatctcagtgcgtttggctcgcagcgagtccttaaaa
gctcagggggaggggcgtcggcgaggaggcgggacgggggcagagtttgttcctcgttcc
cgtagtgatgtggacatggaggactgtgaggagagggaggggccaggactgaggccgtta
catcacagcgcatcatcatcagcctccagcagctccgcacggtcgttggagaacccgacg
ccgccgtacacgcctcggtctcagcgcaggattgtggaagttccggtgtctctgttacct
gacgctccggctctggatgaggacgtgatcgactcgcacaactggcaggacacagtggag
ccgcacatattagcatcgctaacgtcacgagagatcgacagacaggctgtcatctacgag
ctgttcacaacagaagtttctcatctgcgaacactgagggttcttgatcaggtgttttat
cagaagatgcagagcgtcctcagtccagaagagctatcctgtattttcctgaacctccgt
caagtctatgagctgcacgcaagtttatgtgagtccatgaagaagtgcagagaatcagtg
atagttcagggcattggagacatcatgctggccagatttgagggagaggctggagatcag
tttgaggagcaggtttcgcatctgtgcagtcaacagagtccagcgctggagctcatcaag
aacaaacagcgaaaagaccctcgattcgcccacctcatacaggagtgtgaggccagtcct
cactgccggcggctgcagctgaaggatctgctggtgtcagagatgcagcgcttgaccaaa
tatccactgctgctggacaacatcatcaaatacacagagacaagttctcctgatctgccg
ctcctccggagagctcaggcgtgctgtcgtgggattctgcaggaagtgaatgaggacgtg
agggagactgaacaccggcatttgctcagccaataccagcgcagactggatgccacgcct
ctggagagactggccaatcccgtcgcagcgcagtttaggaatctggatctcaccaccaag
aggatggtccacgaggggccgctcacgtggagagtcggcaaagacaaagccattgagatc
caggcgctgctgctctcagacctgctgctcttgctccagcgggggccggacgacaggctc
atcctgcgatgtccgtcacgctcgctgggcggagttacagacctcaaaacacccttctgt
cctgtggtttgcctcaattcctgcctcgtccgccccgtcgccacagacaataaagcgctg
tatgtgatcagcacatccgagaggcagatctatgagctggtggccggaacgttactggag
aaaaacacttggaaagaccagctggaaaagacaatctctgcagccgctcaaggaggatca
accaaaccaaacacaccacgtttcaggtctccaggtgcgggtgtgagattatctgccgat
cagtcagaaggctctgaatcccgcatgtatccagacagagaggatgagatggttctctct
cctgtcgtcacaccggctgatgcagctgaagagtgtccggatgaagatccagacgcgggc
cagaaaaacaaagctggagtggctgaatctgctctccaggacgtggaaactctgcggcag
ctgatcttccgagacctggaggatgggtggagtcaagattcagatgacacgcccactaac
gaaacagccaatgagaggagtccgttcacagacagaccgggaaatgagtcatctgatcct
gcccccagcgaaagttctagccaatgggaggaggagcctgtggaagctccgcctctggag
gtgctgcagcctgctgttcaggtggtgaggaaagctgtgggtgtgggctgttctcttcct
gatgacatcaccgatgatgtcaccgccagccaatcgtctgaggacggaggaaacctgttc
tatctggtgatgtcgacggatcagggtgtttcagacgagagcaccacagacgagctcaaa
gatcttcatcactctgtgttttcgtcatcttttatcaatgaggaggaggagcaggacacg
ccctgtctatcgccaactgaccaatcactgatcgagagccagggtcacagaccaggcctc
agccaatcacagagcagcgtccagcgtcatgtgatcaaaaatgtggatgagatcttcaac
actatggaggagctgatgaagaaactgcagcacctgagggacattgaagcggatcaccac
aaactcctgaagaaactacgcaaaccacttcctgttgacaaaatgtctagtgatggggtc
cacaaatctccaacagcggcgcgactctcttcactggaccgcggagcaggagatggtaag
gagggcgtctcaacggaaccagctcaacctcaaatccagtccactggtttctga
Danio rerio (zebrafish): 571031
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Entry
571031 CDS
T01004
Symbol
arhgef12b
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
dre
Danio rerio (zebrafish)
Pathway
dre04270
Vascular smooth muscle contraction
dre04625
C-type lectin receptor signaling pathway
dre04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
571031 (arhgef12b)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
571031 (arhgef12b)
09153 Circulatory system
04270 Vascular smooth muscle contraction
571031 (arhgef12b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dre04131
]
571031 (arhgef12b)
Membrane trafficking [BR:
dre04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
571031 (arhgef12b)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
Motif
Other DBs
NCBI-GeneID:
571031
NCBI-ProteinID:
XP_009300160
ZFIN:
ZDB-GENE-070705-36
Ensembl:
ENSDARG00000100913
UniProt:
A0A8M3ASS4
LinkDB
All DBs
Position
5:complement(64558648..64693768)
Genome browser
AA seq
1422 aa
AA seq
DB search
MSGTQSTLAERFPKKASRTGSILSKDHPPDKKAKSDKASVPLSHEFDPTGLVQRCVIIQK
DENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHVEVVKLIKSG
SYVALTVLGRPPGLPQIPLSDGEGEEGSPFSLSSPHSPGPIGPERSCSSPSPSERKAASL
PVWGITEDYRNPTSKLLKEIQDIPQNQNQEQLSKPTGQDESISPRPGEGELEDFSGDVDR
PPSWQGDAGTEPLWTNNNMTPVTPCLFPESPCQRETPCHSPKTTPRDSLNSCPSPDAEDT
PDLDSQSSVGSPCSRPVAHIIGAEDEDFGKEQEQMNGQCSCFQSIDLLKSRPAHLAAFIH
HVVSQFDPAPLLCYLYADLYKQSSTKETRRILMDTFFIDKTANLKVTVPESIIADLERTA
HSTNAERKRPEQMSEDVHRQYVQQLQDTLLTDVQKNLEDFRHKRSMGLTLAEAELARLDT
ERMRDRVALEKERSCAEHILSKIEEVLLTSQATEEDKCSTMQFVILSYMKQLGVKVKELR
GLDHKPKLMNPFHKIKKSMKPEKDGIEEKAKKTRFPNVFPQRRPSKIDALSQPKQRTPKP
QLPLGTGEQADGSSLPVRSSQSSEGSDGTNALITSPPYSAPAGQGTDAISRETETGGLPS
SALPKLGEGTVSGDLQDSSSTNTHFDFSNCMLEHLQEEEAETEKTQDSGTPRPDRSRMDP
LGSGEVQSEDDQCVEAELEPPNWQTLVSRDVLSTLTPQEIKRQEVINELFYTERAHLRMM
KVLENLFYQPLIRDAILPPADIKNIFSNLEEIVQLHLSLTEQMAAVRKKNETALIDSIGD
DLLSWFSEEEEDKIKRAVGTYCSNQPFALELIKSKQKKDQRFNAFIQETESNRHCRRLQL
KDIIPVETLRLTKYPLLLENIAKYTEDSEERSKVKRAGECCRKILTHVNQEVKEAENKQR
LEDYQRRLDLSSLKQSENPMIAEFKSLDLTKRKMVHEGPLSWKVNKDKTIELYTLLLEDI
LVLLQRQDEKLILKCHSKNLAGTAETKHIFSPIIKLSTVMVRSVATDNRSFFVLSMSDNG
AQIYELMAQTVSEQKTWQCLITQRADCMKTKLHNIIPLPQTDGEREEVEMINSGVQKLSK
DTEPITLASIQSPVEKDDTEVIPTPIPSTNPFENKSDEEAEEEEENSLQDQAEDDEAFVV
ADLSDRLTFLKQRSRLGIAIDEDEAEVFELQPLIADEALRTLATLRQLLINQFSGQEDTD
RENKSEDQQEHIEMTCPQQGSDDSAAIQSPLENGSDRGENPQELPSGDTGFFETSEDCVS
AGSYMVLEVFAGSGESSTDDDAQGCSVEPVAGGDSGIDLKKLLSSSSQSTGGPNINRQIM
THLRLLQGNLQQLKETEIKYNQLRQRLSEETATDTEENKDKS
NT seq
4269 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcacacagtccacgcttgctgagaggtttcccaaaaaagcgagcaggacagga
agtattctcagcaaggaccatcccccagataaaaaggccaaaagcgacaaggcgtcagtc
cccctctcgcatgagtttgaccccacagggcttgtgcagcgttgtgttatcatccagaaa
gatgagaatggctttgggctgacagtgagcggcgataaccctgtgtttgtacagcttgta
aaagaggatggagctgccatgcgagctggtgttcagactggtgaccggatcataaaggtc
aatgggacgttagttacacattcaaatcatgtagaagttgtaaagctaataaaatcgggc
tcgtatgtggccctgacggtgctggggagaccgcctggcttgcctcagattcccctgtca
gacggcgagggggaagaagggtctccgttctcgctcagttctcctcactccccagggccc
atcggaccagagcgctcctgttcctcccccagcccctcagagcgaaaagcagcctctctg
cctgtatggggcataacagaggactacagaaaccctacatctaaactactgaaggaaatc
caggacattccacagaaccagaaccaagagcagctcagcaaacccactggacaggatgaa
tccatatctccgagaccaggtgaaggagagctggaggattttagtggagatgtggatcga
cccccttcctggcagggtgatgctgggacggagccattatggaccaacaataacatgact
ccagttactccttgtcttttcccagagagcccatgccaaagagagaccccctgccacagc
ccaaagaccacacctcgagacagcctcaactcctgtccctcgccggatgcagaagacaca
cctgacctagattctcagtcaagtgtagggagcccttgctctcgtcctgtagcacatatc
atcggtgctgaggatgaagactttggcaaagagcaggaacagatgaatggccagtgtagc
tgttttcagagcatagacctcctgaaatctcgacctgctcacctggcagctttcatccat
cacgtagtctctcagtttgaccctgcaccgctgctctgctacctctacgctgatctttac
aaacaatccagcaccaaagagacacgacgaatcctcatggataccttcttcatagacaaa
acagctaatttgaaagtaacagtacctgaatccatcatcgctgacctggagaggaccgca
cactcaaccaatgcagagcggaagaggccggagcaaatgtctgaagatgtacaccgacaa
tatgtgcaacaactgcaggacactcttctaactgacgttcagaagaacctagaagacttt
aggcacaagcgcagtatgggtctgacattggctgaagctgaactggcccgtctggataca
gagagaatgagagatcgtgtggctttggaaaaagagcgatcctgtgcagagcacatcctt
tctaagatagaagaagtcctattgacgtcacaagccacagaggaagataagtgtagcacc
atgcaatttgtgatactatcgtatatgaaacagctcggtgtgaaagtgaaggagttgcga
gggctggaccacaaacccaagttaatgaatccattccacaaaataaagaaaagtatgaag
cctgagaaggatggaattgaggagaaagcgaagaaaacacgatttcctaatgtctttcct
cagagacgaccaagcaagattgacgctttatcacagccgaagcagcgtacgccaaagcct
cagctgcctctgggaactggagagcaggcagacgggtcgtctcttcctgtacggagcagt
cagtccagcgagggctcagatggcaccaatgccctgatcacatcaccgccttacagcgct
ccagcaggacagggcacagacgccatcagccgagagactgagactgggggacttccctct
tctgccctgcccaaattgggagagggtactgtctcaggggatttgcaggactcctcatct
acaaacactcactttgacttcagcaattgcatgctggagcatttacaggaggaagaagct
gagactgaaaagacgcaggactctggcacccccaggcctgacaggagcaggatggatccg
ctgggctctggagaggtgcagagtgaagatgatcagtgtgttgaagccgaactcgagcct
ccaaactggcagacactagtgagcagagacgtcctgtccacactcactcctcaggaaatt
aagagacaagaagtcatcaatgagctgttctacacggagcgagcacaccttcgaatgatg
aaggttctggagaatttattttaccagccgctgatcagagatgccatccttcctcctgca
gacatcaaaaacatcttcagcaacctggaggagatcgttcagctgcacttgtctttaacc
gaacaaatggccgccgtacggaagaagaacgagaccgctctcattgactcaataggagat
gatctgctttcctggttcagtgaagaagaggaggataagatcaagagagcggtgggcacc
tactgcagtaaccagcccttcgccctggagctcatcaagagcaaacagaagaaagaccag
cgcttcaatgccttcatacaggagacagagagcaaccgtcattgtcgcaggctgcagttg
aaagacattattcctgtggagacgttacgactcacaaagtatcctcttctgctggagaac
atcgccaaatacacagaggactctgaggagagaagtaaagtgaaacgggctggcgaatgc
tgtagaaagatcctcactcacgtcaaccaggaggtgaaggaagccgaaaacaagcagagg
ctggaggactaccagagaagactggacctgtcctcactgaagcagagcgaaaaccccatg
atagcagagttcaagagcttggacttgaccaagaggaagatggtgcacgaggggccgctg
tcctggaaggtcaacaaagacaaaaccattgagctgtacacgttgctgctggaggatata
ttggtgctacttcaaaggcaggatgagaagctgatcttaaaatgccacagtaagaatctg
gcgggcaccgctgagaccaaacacatcttcagccccatcatcaagctcagcactgtgatg
gtgcgctccgttgccaccgacaacaggtcgttctttgtgctgtcgatgtctgataatgga
gcccagatctatgagctgatggcccagaccgtatcagagcaaaagacgtggcagtgtcta
atcacacaaagagcagactgcatgaagaccaaactacacaacatcattccattacctcag
accgatggggaacgtgaagaggtggagatgatcaactctggtgttcagaagctaagcaaa
gacactgaaccgattactttagcgagcatccagtctccagtagaaaaagacgacactgag
gtcatcccaaccccaatacccagcaccaacccctttgagaacaaatctgatgaggaggct
gaagaagaggaggaaaactctctacaggaccaggctgaagacgatgaagcgtttgttgtg
gcagatctgagcgatcgactgacgttcctgaaacagcgctccagactcggcatcgccatc
gatgaggacgaggccgaagtcttcgagctgcagccgctcatagctgatgaagctctcagg
acattggcgacattgaggcaactcctgatcaaccagttttccggtcaggaggacacagac
agagagaacaagagtgaagatcaacaggagcatatagagatgacgtgccctcagcagggc
tcagacgacagcgctgccatccagtctccgcttgagaacggctcagacagaggagagaat
ccacaggaactaccatccggggacaccggcttctttgagacgtctgaagattgtgtgtct
gcaggcagttatatggtgctggaggtgtttgcgggctcaggagagagcagcacagatgac
gatgcgcagggctgcagtgtggagcctgtggctggtggagattcaggcatcgacttgaag
aagctcctgtcttcatcttctcaaagcactggaggacccaacatcaacagacagatcatg
acacacttacgtctactacagggcaacctgcagcagctgaaggagaccgaaatcaagtat
aaccagctacgccaaaggctatcagaggaaacagctactgacacagaggaaaacaaagat
aaaagttag
DBGET
integrated database retrieval system
