Danio rerio (zebrafish): 573111
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Entry
573111 CDS
T01004
Symbol
tpmt.2
Name
(RefSeq) thiopurine S-methyltransferase, tandem duplicate 2
KO
K00569
thiopurine S-methyltransferase [EC:
2.1.1.67
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00983
Drug metabolism - other enzymes
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00983 Drug metabolism - other enzymes
573111 (tpmt.2)
Enzymes [BR:
dre01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.67 thiopurine S-methyltransferase
573111 (tpmt.2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
TPMT
Methyltransf_11
Methyltransf_25
UDPG_MGDP_dh_N
Motif
Other DBs
NCBI-GeneID:
573111
NCBI-ProteinID:
NP_001028758
ZFIN:
ZDB-GENE-041010-177
Ensembl:
ENSDARG00000028012
UniProt:
Q5XJQ2
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All DBs
Position
19:47299166..47309583
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AA seq
246 aa
AA seq
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MSAQADREVDLSEWENCWQEGRTGFHRSDVHNLLKANVDKLICGRPEVRFFFPLCGKAVD
MKWLADLGHTVVGVDISEKGIKEFFQEQNLEYNEEAVADIPGAKLFKESPQRNEPPTIPA
KSTDGKISIYQCDLYKFSSAVAGHFGGIWDRGALVAINPCDRQKYASLLVSLMSSDCRYL
LDTLEYNPELYKGPPFFVSEDDIKTVFGGSCNIDLLQSVGGLEEGHKSWRLDSLTEKLYL
LTTKTQ
NT seq
741 nt
NT seq
+upstream
nt +downstream
nt
atgtctgcgcaggccgaccgtgaggtggatctgtccgagtgggagaactgctggcaggaa
ggaagaaccggtttccacagatctgatgtgcacaatttgctgaaggctaatgtggacaaa
ctcatatgtggacgaccggaggttcggttcttcttcccgctttgtggaaaggctgtagat
atgaaatggctggctgatttggggcacacggttgttggtgttgacatttctgaaaaagga
attaaagagtttttccaagagcaaaatctggagtataatgaagaagctgtggcagatatt
cctggagcaaagcttttcaaggaatcgccacagcggaatgaaccaccaactattccagca
aagagcacagatgggaagatctccatctatcagtgtgatttatacaagttctccagtgct
gttgcgggacactttggagggatctgggatcgaggagcactggtggctataaacccatgt
gatcggcaaaagtatgcgagtctgcttgtgtctttaatgagcagcgactgcaggtatctg
ctggacacgctggaatataaccctgagctttataaaggtccaccattcttcgtgtcagaa
gacgacataaaaactgtattcggaggaagctgtaatattgatcttctgcagagtgtgggt
ggcttggaggaagggcacaaatcatggagactggattcactcacagagaaactttacctg
ctcactactaaaactcaataa
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