Danio rerio (zebrafish): 768185
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Entry
768185 CDS
T01004
Symbol
hsd17b7
Name
(RefSeq) 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
KO
K13373
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:
1.1.1.62
1.1.1.270
]
Organism
dre
Danio rerio (zebrafish)
Pathway
dre00100
Steroid biosynthesis
dre00140
Steroid hormone biosynthesis
dre01100
Metabolic pathways
Module
dre_M00101
Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:
dre00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
768185 (hsd17b7)
00140 Steroid hormone biosynthesis
768185 (hsd17b7)
Enzymes [BR:
dre01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
768185 (hsd17b7)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
768185 (hsd17b7)
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GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
Epimerase
SDR
Rdx
NAD_binding_10
Motif
Other DBs
NCBI-GeneID:
768185
NCBI-ProteinID:
NP_001070796
ZFIN:
ZDB-GENE-061013-378
Ensembl:
ENSDARG00000088140
UniProt:
Q08BC5
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Position
6:complement(37482423..37497347)
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AA seq
340 aa
AA seq
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MKKVVLVTGANSGIGLALCERLLNEDAQIELCLACRNMQRAEAARKALLVSHPQARVSLL
HLDVGNMHSVVKGAEEFKKKFNRLDYLYLNAGIMPNPTVDHVAFYRGLFSRNAIKMLTTG
EGILTQEDKVTPIGLQEVFATNLFGHFLLVKELEPLLCQTEHNSLVIWTSSSNAQRSSFN
LEDVQHKNGPLPYSSSKYASDLLSLALNRHYNSQGMFSSVICPGLVMTNLTYGILPSLFW
TIIMPILFLIRIFTNSFTLSPYNGAEALYWLFKQKPESLDPMAKYHSLTSGLGNNYTRPS
KMDLDENMSEAFYVKLLELEDTVRKKLRAENPDFKERNGM
NT seq
1023 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaagtagttttggtaaccggtgcaaacagtggcattggtcttgcactgtgtgag
cgtctcctgaatgaggatgcccagatcgagctctgtctggcctgcaggaacatgcaaaga
gctgaagctgcccgaaaggctctactcgtatctcatccacaggctcgggtttctctgttg
cacttagatgtgggcaacatgcactctgtggtcaagggtgcagaggagttcaagaagaag
tttaacagattggactatctgtatctcaatgctggaatcatgcctaatcccacggtggat
cacgtagccttttatcggggcctgttttctagaaatgcgattaaaatgttgaccacgggg
gagggtattctgacccaggaagataaggtcacacccattggtttgcaggaggtgtttgct
actaatctttttggtcatttccttctggtgaaagaactggagcctttattgtgccagaca
gagcacaattctttagtcatctggacgtcctccagtaatgcccagcgatcctcctttaat
ctcgaagatgtgcagcataagaacggccctttgccctacagctcgtcgaaatatgcttca
gacctgcttagcttagccttgaaccgccactacaacagccagggtatgttctcatcagtg
atctgccctggtctggtcatgactaacctcacctatggcattctgccttcattgttctgg
actatcatcatgccaatattgtttcttataaggatattcaccaattcttttaccctctca
ccttacaatggagcggaggctttgtattggctgttcaagcagaaacctgagtctctggac
ccgatggccaaataccatagtttgacctctgggctcggaaacaattacacccgaccaagc
aagatggatcttgatgaaaacatgtcagaggccttctatgtgaagctgttagagctggaa
gatacagtgcggaagaagctaagagcagagaatcctgatttcaaagaaagaaatggaatg
tga
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