Danio rerio (zebrafish): 797406 Help Entry 797406            CDS       T01004                                  Symbol espl1 Name (RefSeq) separin isoform X1   KO K02365   separase [EC:3.4.22.49] Organism dre  Danio rerio (zebrafish) Pathway dre04110   Cell cycle dre04114   Oocyte meiosis Brite KEGG Orthology (KO) [BR:dre00001]  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     797406 (espl1)    04114 Oocyte meiosis     797406 (espl1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:dre01002]     797406 (espl1)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:dre03036]     797406 (espl1) Enzymes [BR:dre01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.49  separase      797406 (espl1) Peptidases and inhibitors [BR:dre01002]  Cysteine peptidases   Family C50: separase family    797406 (espl1) Chromosome and associated proteins [BR:dre03036]  Eukaryotic type   Sister chromatid separation proteins    Separase     797406 (espl1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C50 TPR_12 CHAT Motif Other DBs NCBI-GeneID:  797406 NCBI-ProteinID:  XP_001337869 ZFIN:  ZDB-GENE-030131-5188 Ensembl:  ENSDARG00000075354 UniProt:  A0A8M1Q1L6 LinkDB All DBs Position 6:complement(39668848..39700893) Genome browser AA seq 2182 aa AA seqDB search MALKSLKTEDYVQQLSCVKDTIVLHNELKKHVDGGLGPYGRTMCDRIIRACNQRLGNGAV DAGLQERIVELVELAVQGFQLLEESGMQSTPFYLEKIVFHILQKVASLGAHGPACRLGQL VYRRLKCLSAEIDDFNVLVRNCFAVLWNSLLSNKPSASTLPPRDRLHCQLQALTFRLLEQ GSSSSSSPSKVPLFVEEAVVEYERSCGGFTQDDVSFLTSELRELFSGAFINPQDSASTSS LLAVWCEVAFKVSKLLCKSSFSPEAVELLRGTLKEVNGHVGLRSALGLADRAVQMQCVLS SGGECSKSFTECARALRMLPCAMSSSESHALLEACQLVVWTLEASQCKGMDVTTLLACFS FLEEYQEFLLAQQKNSFSLQVQYSLCFSFYQGFICTYDSLHASQVSVGETLDRVLLFCRS TAGRMLAELRTLNNDNLLLKAVCAVNNVVYELFNRKLYEGAFGLSMIVCQELCKDCPPSL PMDRVNRCFMLTVQCSRRAGHLEQALDWIVRWIQALGSQILDHLTEPVSMWVKTKCDAAR AGEDDTRLRTLRDGLGESLVDEEVMMCLLEEELRVYKEQTGDTAQERYNTLCDLLEICHE ETPHTLRRATYLCEMAQVVCYQDFSQQTDCSAVDFTHEALRLLEAEPETAENTDRLKDEK AHASLWLYICTLESNLQEAVDTEKRLCAVQEENKRDVNMDPVPTNDLEYEDKQKSQESQL VYDGLRFNLLAHSKQSEPLDKCLSLWRSLLKGAVPAVRDPKLTASSMTLMAALYTLMGKH LQALEGYQLAATLFHVLGDGQSSANAFCHSTRILLYLGSPQLAQVDLEKAEKSLSSVTIS EGTSIISMLAMLQKAQLHYALGQVESGVSCLMEVIKESAQHHSKSWYLLRARALQTASEY LSLDTLALNSQLRQSIMQQGLKTPDTAQYEGLKLLCSLVMMLLGNGFYGAPGPNTDTRFV DKGDSVVFKWLLLSEVLVCSERMVITRSSSGAVHEAKAQCLEALKLATKLQTLSHCAELL VLKAELELMKGATEASSLDLEQVRHLLDLCTDFGQGRQQKSEVKIKPRKGRPAAPSSSGH ISEEEDDLSGILSSRALPKEPVENMARLGSQGASPPLKPKCQHGLSCLTHEETCSCLCCT ELSVARVSIHWALLQADLQTDPERSLRLRQSARKRCRYVVTKLQRSLAALVHSKKSPNVC LSLLQAEQGKVHLGAVLQLLRTGDKGKAAILWEEIEAGLEAVTPKGALTPELGPIRATLL GAKAVACCLALAMKKQCIPEELFSSLWHWNPPKVKPQLKSKHRSKSPDAAPLEAGVKHNP KVKSGLEENESRKTKETTVISKKAKDSVPKITITKSSMVFKTPKATRTTRPKSVSTSTGI SDLRAFDFNNEVPDISVNFTPSLHRSTNQSATAKSKASSKGSFQVYKDSSPAAEKAVVVP AAPKRTKRSRFKVEFSDESDNDAAPLAVMEKSEKKKNTFKTSRTLKPTLNTIPSDTKLVS STVDPEPSRRTRTTKKSTALPSIGGLSSEEELGVSSQTRTRRGRPKKSTSSADTEEPERM RMIKEEEQRVLLNVSMEELRGSDTETKDTGSPDADCEVLRRDLGADFGRECFSELRRAGQ NGSGSHTALPHATTSPADLSVETVQSYLRSSWLLLHHFPFPSLYPHICSLLAQSFGQTDP IITAMLHAQALGVSTRHHMTRHVVNQFRKLKKSCNDVAEGLGALSLEETSGATQSKKLSA LEQIFSFTASNPMQFPQTHCQQFTQQLEDLPAGVTVCLLSLTGVHPDEIGNTILLTRLER GSTPITVRIPTADREQSVAGLLEEMDGVLKGQKEVSTVAEKSQWWDGRKALDARVEKMLE EMEEALGVWRTLFLPLTSDPKLDVQVKSLQKALKSTKITRDTLKVILSASPLLSLPDLQC LLEGMNVQDKDLLKLLQRGVAELRGREEPQGHTVLILDKYLQRLPWENIACLKSQSVTRM PSLHAVLGHSHLREVDTSCVLSCGVNPKQVYYVLNPDGNLPDTENRFKEWFTGERTWQGV CGRAPDPEKLQEAVTTKDLYIYIGHGAGARFLDAQRVLKVPVRTAALLFGCSSAALSVLG QQEGTGIILSYLTAGCPLVLGNLWDVTDRDLDRFTSALLQSWLSAGSGSSLLQHLAKSRS ATHLKHIIGAAPIAYGLPVHIH NT seq 6549 nt NT seq  +upstreamnt  +downstreamnt atggcattaaagagcttgaaaacagaagattacgttcagcagttatcctgtgtcaaggac accatagtcctccacaacgaactgaagaaacatgtggatggtggcttgggtccttatggt cgcacaatgtgtgatcgtatcatcagagcctgcaaccagcggctgggcaacggcgctgtg gatgctggccttcaggagcggatagtggagctggtggaactggctgtccaagggtttcaa ctgcttgaagagtccggcatgcagagcacccccttttatctggagaaaatagtctttcac atcctacagaaagtcgcaagccttggagctcatggtcctgcttgtcgactgggtcagctc gtgtatagaagactgaaatgtttgtctgcagagattgatgactttaatgtcctggtgcgg aattgctttgcagtcttgtggaacagtctcctctctaacaaaccgagtgcttccaccctc cctccacgagacagactccactgtcagctgcaagctttaacattcagactccttgaacag ggctccagctcgtcctcttccccatccaaagttcctctgttcgtggaggaagcagtagtg gagtacgaacgatcatgtggaggttttactcaagacgatgtgagttttctgacctctgaa ttgcgtgagctgttctctggtgctttcatcaatcctcaggactctgcatcaacttcttca ctgctggctgtgtggtgtgaggtggcatttaaagtgtctaaactgctctgcaaaagtagc ttttcacctgaggctgttgaactcttgcgaggcactctgaaggaggttaatggccacgtt ggcctgcgttcggctctgggtctggcagaccgggcagtgcagatgcagtgtgtgttaagt tctggaggtgaatgcagtaagagcttcactgaatgtgcccgtgctctccggatgttgcct tgtgccatgtccagctcagagtctcatgccctgttagaggcttgtcagctggtggtttgg acgttggaagccagtcagtgtaaaggaatggatgtgaccactttgctggcttgtttttcc tttttggaagaatatcaggaatttctgcttgcacagcaaaagaactcgttttcgctgcag gtccaatactctctttgtttcagtttttaccagggcttcatctgcacatatgatagtctt catgcttctcaggtgtctgtgggcgagaccttggacagagtgctattgttctgccggtcg accgcaggacgtatgcttgctgaactgcggacactcaataatgacaacttgctgcttaaa gcagtgtgtgcagtgaataatgtggtgtacgagctgtttaacaggaagctgtatgaagga gcctttggattgtcgatgattgtgtgtcaggagctctgtaaggactgcccgccctctctt cctatggatcgggtcaaccgctgtttcatgctgacagtgcagtgtagtcgccgcgcaggc catctggagcaggctctggactggattgttcgctggattcaggctttgggctcacagatt ttggatcatctcactgaacctgtgtcgatgtgggtcaaaactaagtgtgatgccgccaga gcaggcgaggatgacacacgcctgaggactctgagggacgggttaggagaatccttagtg gatgaggaggttatgatgtgtttgttagaggaggagttgcgtgtatataaggagcagact ggagacacagcacaggaacgctacaacacactctgcgacctcttggaaatctgccatgaa gaaaccccacacacactaagaagagctacgtatctgtgtgagatggcacaggttgtgtgc tatcaggacttcagccagcagactgactgctcagcagttgattttacccacgaggctttg cggttgctggaagcagaaccagagacggcagagaatactgataggctgaaggatgagaaa gcccacgcttccctgtggctctatatctgcactcttgagtctaacctgcaggaggctgtg gacacagagaagcgtttgtgtgcagtgcaggaggagaataaaagagatgtgaatatggat cctgttcccacaaatgatctggagtacgaggacaaacagaaatcacaagagagccagtta gtctacgatggactacgcttcaacctgctggctcacagcaagcaaagtgaacctctagat aaatgtttgtctctatggcggagtctcctcaagggggctgtgcctgcagttagagaccct aaactcacagcttcttccatgactttgatggctgccctatacacacttatgggcaagcac ctgcaagctctggagggatatcagcttgctgccacccttttccatgtacttggtgatggc cagagtagtgccaatgccttctgccactctaccaggatcttgctttacctgggttcaccg cagcttgcacaggtggacttagaaaaagcagaaaagagcttgtcatctgtcaccatctct gagggcacatctattatctccatgctggccatgttgcaaaaagcacagctacactatgct ctaggacaggtggagagtggcgtgtcctgcctgatggaggtgataaaggaatctgctcag catcattctaagagctggtacctgctcagggctcgagcactgcagacagccagtgaatac ttgagtctggacacactggctttgaactcacagctacgccagagcatcatgcagcagggt ctaaagactccagacactgctcaatatgaagggttgaagctgttgtgtagcctggtgatg atgttattgggcaacgggttttacggagcgcctggaccaaacactgacactcgctttgtg gataaaggagacagtgttgtgtttaagtggctgctgctgagtgaagtgctggtgtgctcg gagagaatggtgatcaccaggagcagcagcggagccgttcatgaagctaaagctcagtgt ctagaggctctcaaactggccaccaaactacagacactcagccactgtgctgagctgttg gtgctgaaggcagagctggagctgatgaagggtgcaactgaagctagtagtttagaccta gagcaagttagacatttacttgatctctgcacagattttggccagggacgacaacagaaa tctgaagtgaaaatcaaaccacgcaaaggtcgtcccgctgccccttcttcctctggtcac atctctgaggaagaggatgatctgagtgggatcctcagctctcgtgcccttccgaaggag cctgtggagaacatggctagattaggaagccaaggagcttctccccctctaaagcccaaa tgccagcatggcctctcctgtctgacccatgaagagacctgctcttgtctctgctgcact gagctcagcgtggctcgagtcagcatccactgggcactattacaggcagatctccagaca gatcccgaacgctctctcagactacgccagtctgccaggaaacgctgccgctatgttgta actaaacttcagagaagtttggcagcacttgtacactccaaaaaatcacctaatgtctgc ttgtcactgcttcaggctgaacagggtaaagtgcatctgggtgctgtgcttcaactgctc agaactggagacaaagggaaagctgccatcttgtgggaggagatagaagcaggattagag gcagtgacacctaaaggagcactgacaccagaacttgggcctatcagagctactctactg ggggctaaagccgtagcctgctgcttggcgttggcaatgaagaaacagtgtatacccgaa gagctgttttcttcattgtggcactggaatccaccaaaggttaaaccgcaattaaaatct aagcatcgatccaagagtccggacgcagctcctctagaggcaggtgttaaacataaccct aaagttaagagtggacttgaggagaatgaaagcagaaaaaccaaagagaccactgtcatt tcgaagaaagctaaagactctgtgcccaaaattaccatcacaaaatcctccatggttttt aaaacgcccaaagcaacgagaacaacccggcccaaatctgtctccactagcactggcatc agtgacctgagagcatttgacttcaataatgaggtgcctgacatttcagtcaacttcaca ccatcattacaccgatctacaaaccaaagtgcgactgcaaagtcaaaagcgtcctcaaag ggttcgttccaggtttacaaagattcttctcctgctgcagagaaagctgtagttgtcccg gctgctcctaaacgaacaaagcgttctcgcttcaaggttgagttcagcgatgaaagcgac aacgatgctgctcctcttgctgtaatggaaaagtcagagaaaaagaaaaacacctttaaa acatcacgcaccttgaaaccaacccttaacaccatccctagtgacaccaaacttgtgagc tccacagtagatccagaaccctccagacgaacacggaccactaagaaaagcacagctctt ccctccattggtggcctctcttctgaggaagaacttggagtatcttcacagacacgtacg cgtagaggacgaccaaagaagagcaccagctcagcagacacagaggagccagagaggatg aggatgattaaggaggaagaacagagggttcttttgaatgtcagcatggaggagctcaga ggctctgacactgagacaaaagacactggaagtccagatgctgactgtgaggtcttgagg agagatctaggtgcagattttgggcgagagtgtttcagtgagctcaggagagctggacag aatggatcaggatctcacacagctctgccacatgcaactacatctcctgcagacttgtca gtagagacggtccagtcatacctgcgctcctcatggctcctcctgcaccacttcccgttt ccttctctttatcctcacatctgctcattactcgctcagtcattcggtcaaacggacccc atcatcacagcaatgctgcatgcacaggcactgggagtgtccactcgccaccatatgacc cgtcacgtggttaaccagttcagaaagttgaagaaatcctgtaacgatgtagcagaaggt cttggagctctgagtctggaggaaacatctggagcaacgcagtcaaagaaactctctgcg ttggagcagatcttttcattcacagcatcaaacccaatgcagtttccacagacacactgt cagcagttcacacagcagctggaagatctacctgcaggagtgaccgtatgcttgctgtca ctgacgggggtgcatcctgatgaaattggcaacactattcttctgacccgactggagcgc ggctctaccccaatcacagttcgaatccccactgcagacagagagcaatctgttgctggc ctgttggaagaaatggatggagtcttgaaaggacaaaaggaagtgagcacagtggctgag aaatcacagtggtgggacggaaggaaggctttagatgcccgtgtggagaaaatgctggag gagatggaagaggctttaggagtgtggcgaactctttttctgcctttgacctctgatcct aagcttgatgttcaggtaaagagcctccaaaaggctcttaaatcaacaaagatcacacgg gacactctcaaggtgattctatcagcgtctccactgctgtccctgccagacctgcagtgt cttctggaaggaatgaatgtgcaggacaaggacctgctgaagctcctgcagagaggcgtg gctgaactgagagggagggaggagccacagggacacactgttctgattttagacaagtac ttgcagaggttgccgtgggagaacattgcttgtctgaagtctcagtcggtcactcgaatg ccctcattacacgcggtgcttggacacagtcatctgagagaggtggatacaagttgtgtt ctatcttgtggtgtgaaccctaagcaggtttactatgtgctaaacccagatggaaacctg cccgacactgagaatcgcttcaaagagtggtttacaggtgaacgaacatggcagggggtt tgtggaagggctcctgatccggagaaactacaagaggctgtgaccactaaagatctctac atatacatcggacatggtgcaggagcccgctttctggatgcgcagagagttttgaaggtg cctgtgaggaccgcagctcttctgttcggctgcagtagtgctgctctcagtgtgcttggt cagcaggagggaacgggcatcatcctcagctacctgaccgctggatgtccattggtgctg ggtaacctgtgggatgtgacagatcgtgacttggatcgattcacatcggctctgctccag tcttggctctctgctggttctggctcttcacttcttcagcatttggcgaaatcacgcagc gcaactcatttaaaacacataatcggtgctgcgcccattgcgtatggtttaccggtgcat atacactag

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