Desmodus rotundus (common vampire bat): 112306749 Help Entry 112306749         CDS       T05907                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism dro  Desmodus rotundus (common vampire bat) Pathway dro01524   Platinum drug resistance dro04010   MAPK signaling pathway dro04115   p53 signaling pathway dro04148   Efferocytosis dro04210   Apoptosis dro04215   Apoptosis - multiple species dro04623   Cytosolic DNA-sensing pathway dro04650   Natural killer cell mediated cytotoxicity dro04657   IL-17 signaling pathway dro04668   TNF signaling pathway dro04726   Serotonergic synapse dro04932   Non-alcoholic fatty liver disease dro04933   AGE-RAGE signaling pathway in diabetic complications dro04936   Alcoholic liver disease dro05010   Alzheimer disease dro05012   Parkinson disease dro05014   Amyotrophic lateral sclerosis dro05016   Huntington disease dro05020   Prion disease dro05022   Pathways of neurodegeneration - multiple diseases dro05132   Salmonella infection dro05133   Pertussis dro05134   Legionellosis dro05145   Toxoplasmosis dro05146   Amoebiasis dro05152   Tuberculosis dro05160   Hepatitis C dro05161   Hepatitis B dro05162   Measles dro05163   Human cytomegalovirus infection dro05164   Influenza A dro05165   Human papillomavirus infection dro05167   Kaposi sarcoma-associated herpesvirus infection dro05168   Herpes simplex virus 1 infection dro05169   Epstein-Barr virus infection dro05170   Human immunodeficiency virus 1 infection dro05200   Pathways in cancer dro05203   Viral carcinogenesis dro05205   Proteoglycans in cancer dro05206   MicroRNAs in cancer dro05210   Colorectal cancer dro05222   Small cell lung cancer dro05416   Viral myocarditis dro05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:dro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112306749 (CASP3)    04668 TNF signaling pathway     112306749 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     112306749 (CASP3)   09143 Cell growth and death    04210 Apoptosis     112306749 (CASP3)    04215 Apoptosis - multiple species     112306749 (CASP3)    04115 p53 signaling pathway     112306749 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     112306749 (CASP3)    04650 Natural killer cell mediated cytotoxicity     112306749 (CASP3)    04657 IL-17 signaling pathway     112306749 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     112306749 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112306749 (CASP3)    05206 MicroRNAs in cancer     112306749 (CASP3)    05205 Proteoglycans in cancer     112306749 (CASP3)    05203 Viral carcinogenesis     112306749 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     112306749 (CASP3)    05222 Small cell lung cancer     112306749 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112306749 (CASP3)    05161 Hepatitis B     112306749 (CASP3)    05160 Hepatitis C     112306749 (CASP3)    05164 Influenza A     112306749 (CASP3)    05162 Measles     112306749 (CASP3)    05168 Herpes simplex virus 1 infection     112306749 (CASP3)    05163 Human cytomegalovirus infection     112306749 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     112306749 (CASP3)    05169 Epstein-Barr virus infection     112306749 (CASP3)    05165 Human papillomavirus infection     112306749 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     112306749 (CASP3)    05133 Pertussis     112306749 (CASP3)    05134 Legionellosis     112306749 (CASP3)    05152 Tuberculosis     112306749 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     112306749 (CASP3)    05145 Toxoplasmosis     112306749 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     112306749 (CASP3)    05012 Parkinson disease     112306749 (CASP3)    05014 Amyotrophic lateral sclerosis     112306749 (CASP3)    05016 Huntington disease     112306749 (CASP3)    05020 Prion disease     112306749 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     112306749 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112306749 (CASP3)    05416 Viral myocarditis     112306749 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112306749 (CASP3)    04932 Non-alcoholic fatty liver disease     112306749 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     112306749 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112306749 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:dro01002]     112306749 (CASP3) Enzymes [BR:dro01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      112306749 (CASP3) Peptidases and inhibitors [BR:dro01002]  Cysteine peptidases   Family C14: caspase family    112306749 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  112306749 NCBI-ProteinID:  XP_024418512 LinkDB All DBs Position Unknown AA seq 288 aa AA seqDB search MQESAQYIKVPMENAENSVDSKSVKNSETRLIHGSKSMDSGISLDCSYKMDYPEMGVCII INNKNFHKNTGMACRSGTDVDAANLRETFMNLKYEVRNKNDLTHEEMVELMRNVSEEDHS KRSSFVCVLLSHGEEGVIFGTNGAVELRDLTRFFRGDCCRSLTGKPKLFIIQACRGTELD CGIETDSGVDDDMTCQKIPVEADFLYAYSTAPGYYSWRNAKDGSWFIQSLCTMLKQYANK LELMHILTRVNRKVAIEFESFSFDPNFHAKKQIPCIVSMLTKELYFYH NT seq 867 nt NT seq  +upstreamnt  +downstreamnt atgcaggagtcagcccagtatataaaagttcccatggagaacgctgaaaactcagtggat tcaaagtccgttaaaaattcagaaacaaggctcatccatggcagtaaatcgatggactct ggaatatccctggactgtagttacaagatggattatcccgaaatgggcgtgtgcataata atcaataataagaactttcataaaaatactggaatggcatgtcggtctggtacagatgta gatgcagcaaacctcagggaaacgttcatgaacttgaaatacgaggtcaggaacaaaaat gatcttacacacgaggaaatggtggaattgatgcgcaatgtttctgaagaagaccatagc aaaaggagcagttttgtctgcgtgcttttaagccacggggaggaaggagtcatttttgga acaaacggagctgttgagctgagagacttaacacggtttttcagaggggattgctgtaga agtctcactggaaaacccaaacttttcattattcaggcctgccgaggcacagagctggac tgcggcatcgagactgacagcggcgtcgatgatgacatgacgtgtcagaaaattccagtg gaggcagacttcctgtatgcgtattctacggcgcccggttactattcctggagaaatgcg aaggatgggtcctggttcatccagtcactctgcactatgctgaaacagtacgcaaacaag ctcgagctcatgcacattcttactcgggttaaccgaaaggtagcgatcgaatttgagtcc ttttcctttgacccgaattttcatgcaaagaaacagattccgtgcattgtttctatgctc acaaaagagctgtatttttatcactaa

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