KEGG   DISEASE: らい性結節性紅斑
エントリ  
H01473                                                             

名称    
らい性結節性紅斑
概要    
Reactional states of leprosy are expressions of immunological disturbance and are generally divided into two variants: type 1 (Jopling's type I or reversal reaction) and type 2 (Jopling's type II reaction). Erythema Nodosum Leprosum (ENL), the main symptom of a type-2 reaction in leprosy, is caused by a humoral immune response to Mycobacterium leprae. Patients with ENL become acutely sick with fever, malaise, and crops of painful erythematous nodules. Inflammation often affects other systems causing iritis, neuritis, myositis, lymphadenitis, arthritis, dactylitis, and orchitis.
カテゴリ  
皮膚と軟部組織の疾患
階層分類  
ヒト疾患 [BR:jp08402]
 皮膚疾患
  皮膚と軟部組織の疾患
   H01473  らい性結節性紅斑
ICD-11 による疾患分類 [BR:jp08403]
 01 感染症・寄生虫症
  マイコバクテリア症
   1B20  ハンセン病
    H01473  らい性結節性紅斑
病原体   
Mycobacterium leprae [GN:mle mlb]
治療薬   
サリドマイド [DR:D00754]
クロファジミン [DR:D00278]
コメント  
See also H00344 Leprosy.
リンク   
ICD-11: 1B20.21
ICD-10: A30.8 L52
MeSH: D004893
文献    
  著者
Pocaterra L, Jain S, Reddy R, Muzaffarullah S, Torres O, Suneetha S, Lockwood DN
  タイトル
Clinical course of erythema nodosum leprosum: an 11-year cohort study in Hyderabad, India.
  雑誌
Am J Trop Med Hyg 74:868-79 (2006)
DOI:10.4269/ajtmh.2006.74.868
文献    
  著者
Voorend CG, Post EB
  タイトル
A systematic review on the epidemiological data of erythema nodosum leprosum, a type 2 leprosy reaction.
  雑誌
PLoS Negl Trop Dis 7:e2440 (2013)
DOI:10.1371/journal.pntd.0002440
文献    
  著者
Travassos AR, Antunes J, Pacheco D, Almeida LS, Filipe P, Marques MS
  タイトル
Erythema nodosum leprosum associated with minocycline.
  雑誌
Acta Dermatovenerol Alp Pannonica Adriat 21:39-41 (2012)
DOI:10.2478/v10162-012-0011-6
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