Menstrual cycle-dependent periodic fever (PFMCD) is a rare disease characterized by recurrent high fever with each menstrual cycle. It has been reported mutations in HTR1A cause this disease. HTR1A encodes the serotonin receptor 1A that plays a critical role in serotonergic transmission.
Menstrual cycle-dependent febrile episode mediated by sequence-specific repression of poly(ADP-ribose) polymerase-1 on the transcription of the human serotonin receptor 1A gene.
