Dipodomys spectabilis (banner-tailed kangaroo rat): 122102061
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Entry
122102061 CDS
T07891
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00350
Tyrosine metabolism
dsp00790
Folate biosynthesis
dsp01100
Metabolic pathways
dsp04728
Dopaminergic synapse
dsp04917
Prolactin signaling pathway
dsp05012
Parkinson disease
dsp05030
Cocaine addiction
dsp05031
Amphetamine addiction
dsp05034
Alcoholism
Module
dsp_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
122102061 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
122102061 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
122102061 (Th)
09156 Nervous system
04728 Dopaminergic synapse
122102061 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
122102061 (Th)
09165 Substance dependence
05030 Cocaine addiction
122102061 (Th)
05031 Amphetamine addiction
122102061 (Th)
05034 Alcoholism
122102061 (Th)
Enzymes [BR:
dsp01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
122102061 (Th)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
122102061
NCBI-ProteinID:
XP_042528526
LinkDB
All DBs
Position
Unknown
AA seq
502 aa
AA seq
DB search
MPTPGAAAPQPKGFRRAVSELDAKQAEAIMVRGQSPRFVGRRQSLIEDARKEREAAVAAA
AASSSSSEPGDPLEAVVFEEKEGMATLTLLFSLRAAKPSSLSRAVKVLETFEAKIHHLET
RPAPRPREGGPHLEYLVRLEVPSGDLAALLSSLRHVADDLHSAKEDKIPWFPRKVSELDK
CHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGQPIPHVKYTAEEIATWKEV
YTTLRGLYATHACREHLEAFQLLERFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLS
ARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLAS
LGVSDEDIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEIRAFDPD
TAAVQPYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPRAV
QSSLEGVQDELQTLAHALSALG
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccggtgccgccgcgccccagcccaagggcttccggagggccgtctctgag
ctggacgccaagcaggcggaggccatcatggtgagagggcagtccccgaggttcgttggg
cggcggcagagtctcatcgaggatgcccgcaaggagcgggaggcggccgtggcggctgca
gcggcctcctcctcctcctcggagcccggggacccgctggaggccgtggtgtttgaggag
aaggaagggatggccaccctcaccctgctcttctccctgcgggctgccaagccttcctca
ctgtctcgggctgtgaaggtgttggagacatttgaagccaaaattcaccacctggaaacg
aggccggccccgaggccccgggagggtggcccccacctggagtacttggtgcgcctggag
gtgcccagcggggacctggccgccctgctcagctccctgcgccatgtggcggatgacctg
cacagcgcgaaggaggacaagatcccctggttcccaaggaaagtgtctgagctggacaag
tgtcaccatctggtcaccaagtttgaccctgacctggacttggatcatccgggcttctcg
gaccaagtgtaccgccagcgcaggaagctgatagcagagatagcattccagtataagcag
ggccagcccattccccacgtgaagtacactgcagaagagatcgccacctggaaagaggtc
tacaccacgctgagggggctctatgccacccacgcctgccgggagcacctggaggccttc
cagctgctggagcgcttctgcggctaccgcgaggacagcatcccgcagctggaggacgtc
tcccgcttcctgaaggagcggacaggcttccagctgcggcctgtggccggcctgctgtct
gcccgggacttcctggccagcctggccttccgtgtgttccagtgcacgcagtacatccgc
cacgcctcctctcccatgcactcgcctgagccggactgctgtcatgagctgctcgggcat
gtgcccatgctggccgaccggacctttgcccagttttcccaggacattggcctcgcatcc
ctgggggtctcggatgaggacattgagaaactgtccacagtgtactggttcactgtggag
ttcgggctgtgcaagcagaatggagagctgaaggcctatggtgcggggctgctgtcctcc
tacggggagctcctgcactctttgtcagaggagcctgagatccgggcctttgatcccgac
acggctgccgtgcagccataccaagaccagacctaccagccggtctacttcgtgtcggag
agcttcagcgatgccaaggacaagctcaggagctatgcctcacggatccagcgccccttc
tcggtgaagttcgacccctacacgctggccatcgacgtgctggacagcccccgtgccgtc
cagagctccctggagggcgtccaggacgagctacagacgctggcccatgcgctgagtgcc
cttggctag
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