KEGG   PATHWAY: ecz01053
Entry
ecz01053                    Pathway                                
Name
Biosynthesis of siderophore group nonribosomal peptides - Escherichia coli O45:K1:H7 S88 (ExPEC)
Class
Metabolism; Metabolism of terpenoids and polyketides
Pathway map
ecz01053  Biosynthesis of siderophore group nonribosomal peptides
ecz01053

Organism
Escherichia coli O45:K1:H7 S88 (ExPEC) [GN:ecz]
Gene
ECS88_2416  menF; isochorismate synthase 2 [KO:K02552] [EC:5.4.4.2]
ECS88_0632  entC; isochorismate synthase 1 [KO:K02361] [EC:5.4.4.2]
ECS88_0634  entB; isochorismatase [KO:K01252] [EC:3.3.2.1 6.3.2.14]
ECS88_0635  entA; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase [KO:K00216] [EC:1.3.1.28]
ECS88_0621  entD; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex [KO:K02362] [EC:6.3.2.14 2.7.8.-]
ECS88_0633  entE; 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [KO:K02363] [EC:6.3.2.14 6.2.1.71]
ECS88_0625  entF; enterobactin synthase multienzyme complex component, ATP-dependent [KO:K02364] [EC:6.3.2.14 6.2.1.72]
ECS88_0636  ybdB; putative esterase [KO:K24147]
ECS88_2032  irp; Salicylate synthase [KO:K04781] [EC:5.4.4.2 4.2.99.21]
ECS88_2041  irp; salicyl-AMP ligase YbtE [KO:K04783] [EC:6.3.2.-]
ECS88_2037  irp; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 (HMWP2) [KO:K04784]
ECS88_2039  irp; Thiazolinyl-S-HMWP1 reductase YbtU [KO:K04785]
ECS88_2038  irp; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 (HMWP1) [KO:K04786]
Compound
C00158  Citrate
C00196  2,3-Dihydroxybenzoate
C00230  3,4-Dihydroxybenzoate
C00251  Chorismate
C00315  Spermidine
C00805  Salicylate
C00885  Isochorismate
C02637  3-Dehydroshikimate
C04171  (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate
C05821  Enterochelin
C06769  Vibriobactin
C12037  Pyochelin
C12038  Yersiniabactin
C12216  Mycobactin S
C12219  Corynebactin
C12220  Myxochelin A
C12221  Myxochelin B
C20883  3,4-Dihydroxybenzoyl-[aryl-carrier protein]
C20884  (3,4-Dihydroxybenzoyl)adenylate
C20885  N-Citryl-spermidine
C20952  N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine
C22004  N8,N'8-Citryl-bis(spermidine)
C22069  N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine)
C22273  Petrobactin
Reference
PMID:12040125
  Authors
Crosa JH, Walsh CT.
  Title
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria.
  Journal
Microbiol Mol Biol Rev 66:223-49 (2002)
DOI:10.1128/MMBR.66.2.223-249.2002
Reference
PMID:9818149
  Authors
Gehring AM, DeMoll E, Fetherston JD, Mori I, Mayhew GF, Blattner FR, Walsh CT, Perry RD.
  Title
Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis.
  Journal
Chem Biol 5:573-86 (1998)
DOI:10.1016/S1074-5521(98)90115-6
Reference
PMID:11029592
  Authors
Silakowski B, Kunze B, Nordsiek G, Blocker H, Hofle G, Muller R.
  Title
The myxochelin iron transport regulon of the myxobacterium Stigmatella aurantiaca Sg a15.
  Journal
Eur J Biochem 267:6476-85 (2000)
DOI:10.1046/j.1432-1327.2000.01740.x
Reference
PMID:11112537
  Authors
Keating TA, Marshall CG, Walsh CT.
  Title
Vibriobactin biosynthesis in Vibrio cholerae: VibH is an amide synthase homologous to nonribosomal peptide synthetase condensation domains.
  Journal
Biochemistry 39:15513-21 (2000)
DOI:10.1021/bi001651a
Reference
PMID:10692387
  Authors
Hantash FM, Earhart CF.
  Title
Membrane association of the Escherichia coli enterobactin synthase proteins EntB/G, EntE, and EntF.
  Journal
J Bacteriol 182:1768-73 (2000)
DOI:10.1128/JB.182.6.1768-1773.2000
Related
pathway
ecz00400  Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway
ko01053   
LinkDB

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