 | | PATHWAY: ko01053 | |
Entry |
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Name |
Biosynthesis of siderophore group nonribosomal peptides |
Class |
Metabolism; Metabolism of terpenoids and polyketides
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Pathway map |
ko01053 | Biosynthesis of siderophore group nonribosomal peptides |

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Orthology |
K00216 | entA; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase [EC:1.3.1.28] |
K01252 | entB, dhbB, vibB, mxcF; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] |
K01851 | pchA; salicylate biosynthesis isochorismate synthase [EC:5.4.4.2] |
K02362 | entD, pptT; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7] |
K02552 | menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2] |
K04778 | vibH; vibriobactin synthetase |
K04783 | irp5, ybtE; yersiniabactin salicyl-AMP ligase [EC:6.3.2.-] |
K04784 | irp2, HMWP2; yersiniabactin nonribosomal peptide synthetase |
K04785 | irp3, ybtU; yersiniabactin synthetase, thiazolinyl reductase component |
K04786 | irp1, HMWP1; yersiniabactin nonribosomal peptide/polyketide synthase |
K04787 | mbtA; mycobactin salicyl-AMP ligase [EC:6.3.2.-] |
K04788 | mbtB; mycobactin phenyloxazoline synthetase |
K04789 | mbtE; mycobactin peptide synthetase MbtE |
K04790 | mbtC; mycobactin polyketide synthetase MbtC |
K04791 | mbtD; mycobactin polyketide synthetase MbtD |
K04792 | mbtF; mycobactin peptide synthetase MbtF |
K04793 | mbtG; mycobactin lysine-N-oxygenase |
K12237 | vibF; nonribosomal peptide synthetase VibF |
K12239 | pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69] |
K12240 | pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] |
K12241 | pchG; pyochelin biosynthesis protein PchG |
K15653 | mxcG; nonribosomal peptide synthetase MxcG |
K15681 | mxcL; aminotransferase MxcL |
K24108 | asbA; spermidine-citrate ligase |
K24109 | asbB; 3,4-dihydroxybenzoyl-citryl-spermidine/N-citryl-spermidine--spermidine ligase |
K24110 | asbC; 3,4-dihydroxybenzoate---[aryl-carrier protein] ligase |
K24112 | asbE; petrobactin synthase |
K24147 | entH; proofreading thioesterase EntH |
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Compound |
C04171 | (2S,3S)-2,3-Dihydro-2,3-dihydroxybenzoate |
C20883 | 3,4-Dihydroxybenzoyl-[aryl-carrier protein] |
C20884 | (3,4-Dihydroxybenzoyl)adenylate |
C20952 | N1-(3,4-Dihydroxybenzoyl)-N8-citryl spermidine |
C22004 | N8,N'8-Citryl-bis(spermidine) |
C22069 | N1-(3,4-Dihydroxybenzoyl)-N8,N'8-citryl-bis(spermidine) |
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Reference |
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Authors |
Crosa JH, Walsh CT. |
Title |
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria. |
Journal |
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Reference |
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Authors |
Gehring AM, DeMoll E, Fetherston JD, Mori I, Mayhew GF, Blattner FR, Walsh CT, Perry RD. |
Title |
Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis. |
Journal |
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Reference |
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Authors |
Silakowski B, Kunze B, Nordsiek G, Blocker H, Hofle G, Muller R. |
Title |
The myxochelin iron transport regulon of the myxobacterium Stigmatella aurantiaca Sg a15. |
Journal |
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Reference |
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Authors |
Keating TA, Marshall CG, Walsh CT. |
Title |
Vibriobactin biosynthesis in Vibrio cholerae: VibH is an amide synthase homologous to nonribosomal peptide synthetase condensation domains. |
Journal |
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Reference |
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Authors |
Hantash FM, Earhart CF. |
Title |
Membrane association of the Escherichia coli enterobactin synthase proteins EntB/G, EntE, and EntF. |
Journal |
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Related pathway |
ko00400 | Phenylalanine, tyrosine and tryptophan biosynthesis |
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