KEGG   Enterococcus faecalis OG1RF: OG1RF_10459
Entry
OG1RF_10459       CDS       T01882                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
efi  Enterococcus faecalis OG1RF
Pathway
efi03030  DNA replication
efi03410  Base excision repair
efi03420  Nucleotide excision repair
efi03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:efi00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    OG1RF_10459 (ligA)
   03410 Base excision repair
    OG1RF_10459 (ligA)
   03420 Nucleotide excision repair
    OG1RF_10459 (ligA)
   03430 Mismatch repair
    OG1RF_10459 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:efi03032]
    OG1RF_10459 (ligA)
   03400 DNA repair and recombination proteins [BR:efi03400]
    OG1RF_10459 (ligA)
Enzymes [BR:efi01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     OG1RF_10459 (ligA)
DNA replication proteins [BR:efi03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     OG1RF_10459 (ligA)
DNA repair and recombination proteins [BR:efi03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     OG1RF_10459 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     OG1RF_10459 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     OG1RF_10459 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      OG1RF_10459 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT BRCT_2
Other DBs
NCBI-ProteinID: AEA93146
LinkDB
Position
478041..480071
AA seq 676 aa
MEQQPLTLTAATTRAQELRKQLNQYSHEYYVKDQPSVEDYVYDRLYKELVDIETEFPDLI
TPDSPTQRVGGKVLSGFEKAPHDIPMYSLNDGFSKEDIFAFDERVRKAIGKPVAYCCELK
IDGLAISLRYENGVFVRGATRGDGTVGENITENLRTVRSVPMRLTEPISVEVRGECYMPK
QSFVALNEEREENGQDIFANPRNAAAGSLRQLDTKIVAKRNLNTFLYTVADFGPMKAKTQ
FEALEELSAIGFRTNPERQLCQSIDEVWAYIEEYHEKRSTLPYEIDGIVIKVNEFALQDE
LGFTVKAPRWAIAYKFPPEEAETVVEDIEWTIGRTGVVTPTAVMAPVRVAGTTVSRASLH
NADFIQMKDIRLNDHVIIYKAGDIIPEVAQVLVEKRAADSQPYEMPTHCPICHSELVHLD
EEVALRCINPKCPAQIKEGLNHFVSRNAMNIDGLGPRVLAQMYDKGLVKDVADLYFLTEE
QLMTLDKIKEKSANNIYTAIQGSKENSVERLIFGLGIRHVGAKAAKILAEHFGDLPTLSR
ATAEEIVALDSIGETIADSVVTYFENEEVHELMAELEKAQVNLTYKGLRTEQLAEVESPF
KDKTVVLTGKLTQYTREEAKEKIENLGGKVTGSVSKKTDIVVAGEDAGSKLTKAESLGVT
VWNEQEMVDALDASHF
NT seq 2031 nt   +upstreamnt  +downstreamnt
atggaacaacaaccattaacattaacggcggcgacaactcgtgcgcaagaattaagaaaa
caactcaatcaatattcccatgaatattatgtcaaagatcaaccatccgtagaagattat
gtttacgatcgtttgtataaagagttagtcgatattgaaacggagtttcctgatttaatc
acgccagattcgccgacacaacgtgtaggtggtaaagttttatctggttttgaaaaagct
ccgcatgacattccaatgtatagtttaaatgatgggtttagcaaggaagacatttttgct
tttgatgaacgtgttcgtaaggcgattggtaaacccgttgcttactgttgcgagttgaaa
attgacgggttagcaatttcattacgttatgaaaacggggtgtttgtacgcggagcaaca
cgaggcgatggaacggttggtgaaaacattacagagaacttacgaacggttcgctctgta
ccgatgcgtttaacggagcccatttcagtggaagttcgtggcgagtgctacatgcctaaa
caatcctttgtcgcattgaatgaagaacgtgaagaaaatggccaagatatttttgccaat
cctcggaatgcagcggcgggaagcttgcgccaactagatacaaaaattgtggcgaaacgg
aacttaaatacgtttttatacacagttgctgactttgggccaatgaaagcgaagacgcag
tttgaggcattagaagagctttctgcaattggttttagaaccaatcccgaacggcaatta
tgtcagtcaattgatgaagtctgggcctacattgaagaataccatgaaaagcggagcact
ttgccatacgaaatcgatggaattgtgattaaagtgaacgaatttgcgttgcaagatgaa
ttaggtttcactgtcaaagcacctcgctgggcgattgcctacaaatttccaccagaagaa
gcagaaacagtagtggaagatattgaatggacaattgggcgcacgggggtggtcactcct
actgcagtcatggctcctgtacgagtcgcgggaaccacggttagtcgggcaagtttgcat
aatgcagattttattcaaatgaaagatatccgtttaaatgatcatgttattatttacaaa
gccggcgatattatcccagaagtagcgcaagtcctagttgaaaaacgtgcagccgatagt
cagccttatgaaatgccgacacattgtccaatttgtcatagtgagttggtgcatttagat
gaggaagtggcgttacgttgtattaatccaaaatgccctgcgcaaattaaagaagggctg
aatcactttgtctcacgaaacgcaatgaacattgatggcttggggccacgagtgttagca
caaatgtatgacaaaggattagtgaaagacgtagcggatctgtatttcttaacagaagaa
caattaatgactttggataaaatcaaagaaaaatcagcaaacaacatttatactgccatt
caagggagtaaagaaaactctgtcgaacgtttgatttttggcttagggattcgccatgtg
ggtgcgaaagcggcgaaaattttagcggagcattttggtgatttaccaaccttaagtcgt
gcaactgcggaagaaattgtggctttggattcaattggcgaaacaatcgcagacagcgtt
gtgacgtattttgaaaatgaggaagttcatgaattaatggctgaactggaaaaagcccaa
gtgaacttgacatataaaggtctccggacagaacaattagcagaagtggagtcacctttc
aaagacaaaacagttgttttaacaggaaaattaacgcagtacactcgcgaagaagccaaa
gaaaaaattgaaaatcttggtggaaaagttacagggagtgtttcgaaaaaaactgacatt
gtggttgctggcgaagatgcaggcagtaaattaaccaaagctgaaagcttaggcgtgacc
gtttggaatgaacaagaaatggtcgatgcgttagatgcaagtcatttttaa

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