Eublepharis macularius (Leopard gecko): 129331415
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Entry
129331415 CDS
T09084
Symbol
GPX4
Name
(RefSeq) phospholipid hydroperoxide glutathione peroxidase
KO
K05361
phospholipid-hydroperoxide glutathione peroxidase [EC:
1.11.1.12
]
Organism
emc
Eublepharis macularius (Leopard gecko)
Pathway
emc00480
Glutathione metabolism
emc00590
Arachidonic acid metabolism
emc01100
Metabolic pathways
emc04216
Ferroptosis
Brite
KEGG Orthology (KO) [BR:
emc00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
129331415 (GPX4)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
129331415 (GPX4)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
129331415 (GPX4)
Enzymes [BR:
emc01000
]
1. Oxidoreductases
1.11 Acting on a peroxide as acceptor
1.11.1 Peroxidases
1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase
129331415 (GPX4)
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Motif
Pfam:
GSHPx
AhpC-TSA
Motif
Other DBs
NCBI-GeneID:
129331415
NCBI-ProteinID:
XP_054837933
UniProt:
A0AA97L159
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Position
5:5569249..5581225
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AA seq
194 aa
AA seq
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MSFGRFARRAVLWGVLTARGLTRTMCAQEVDWKSAKSIYEFHAIDIDGNDVSLEKYRDHV
CIITNVASKUGKTGVNYTQFVEMYGRYAERGLRILAFPCNQFGKQEPGTDEEIKAFAAGY
GVKFDLFSKIDVNGGDAHPLWKWMKSQPKGRGTMGNAIKWNFSKFLINKEGQVVKRYSPM
DDPSVIEKDLPPYL
NT seq
585 nt
NT seq
+upstream
nt +downstream
nt
atgagctttggccgtttcgcgagacgcgcagtgctgtggggcgtgttgacagcgcggggc
ttgacgcggacgatgtgtgcccaagaagttgactggaaatctgccaaatccatctatgaa
ttccatgccatagacattgatggcaacgatgtctcgctggagaaatacagggatcacgtc
tgcatcatcaccaacgttgcctccaaatgaggcaagacaggcgtaaactacactcagttt
gtcgagatgtatggcagatatgctgagaggggtttacgcattctagccttcccttgcaac
caatttggcaaacaggagccaggcactgatgaggagatcaaagcttttgctgcaggctac
ggggtgaagtttgacctgttcagcaaaatcgatgtgaatggtggcgatgcccaccctctc
tggaagtggatgaagagccagcccaaaggcagaggcaccatggggaatgcaattaaatgg
aattttagcaagttccttatcaacaaggagggccaggtggtcaagaggtacagtccaatg
gatgacccttctgtgatcgagaaggatctgcccccctacctgtag
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