Echinops telfairi (small Madagascar hedgehog): 101642018
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Entry
101642018 CDS
T08707
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00350
Tyrosine metabolism
etf00790
Folate biosynthesis
etf01100
Metabolic pathways
etf04728
Dopaminergic synapse
etf04917
Prolactin signaling pathway
etf05012
Parkinson disease
etf05030
Cocaine addiction
etf05031
Amphetamine addiction
etf05034
Alcoholism
Module
etf_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
101642018 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
101642018 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
101642018 (TH)
09156 Nervous system
04728 Dopaminergic synapse
101642018 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
101642018 (TH)
09165 Substance dependence
05030 Cocaine addiction
101642018 (TH)
05031 Amphetamine addiction
101642018 (TH)
05034 Alcoholism
101642018 (TH)
Enzymes [BR:
etf01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
101642018 (TH)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
Metal_resist
LTP_2
Motif
Other DBs
NCBI-GeneID:
101642018
NCBI-ProteinID:
XP_004717236
LinkDB
All DBs
Position
Unknown
AA seq
493 aa
AA seq
DB search
MPTPGAATPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVVAAAAEP
GDPLEAVAFQEQNGRALLNLLFSLRGTKPSPLSRVVKVFETFEAQIYHLETRPAARPQDG
GSHLEYFVRCEVPRADLAALLSSVRRVSEDLRGAQEDKVPWFPRKVSELDQCHHLVTKFD
PDLDLDHPGFSDQTYRQRRKLIADIAFQYRQGDPIPRVEYTAEEVATWKEVYSTLKGLYA
THACREHLEAFELLERYSGYGEDSVPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLA
FRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLANRTFAQFSQDIGLASLGASDEEIE
KLSTLYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSAEPEVRPFDPDAAAVQPYQD
QTYQPVYFVSESFSDARDKLRSYAARVRRPFSVRLDPYTLAVEVLDSPRSLGRSLEAVQD
ELQALGHALTSIG
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccggtgctgccacaccacagcccaagggcttccgccgggccgtgtcagag
ctggacgccaagcaggctgaagccatcatgtccccccgcttcatcgggcggcggcagagc
ctcatcgaagatgcccgcaaggagcgggaggcggccgtggtggcggcggcggcggagcct
ggggaccccctggaggccgtggctttccaggagcagaacggccgggccctgctgaacctg
ctcttctctctgcggggcaccaagccctcgcccctgtcgcgtgtcgtgaaggtgtttgag
acatttgaagcccaaatctatcacctggagacccggccggctgccaggcctcaggatggg
ggctcccacctggagtactttgtccgctgcgaggtgccccgagcggacctggctgctctg
ctcagctccgtgcgccgggtgtcggaggatctacggggggctcaggaggacaaagtgccc
tggtttccaaggaaagtctctgaactagaccagtgccatcacctggtcaccaagtttgac
ccggacctggacctggaccatccgggcttctcggatcagacctaccggcagcgcaggaag
ctgattgcagacatagccttccagtaccggcagggtgacccaattccccgagtggagtac
acggcagaggaagtcgccacctggaaggaggtgtactccacgctaaaggggctgtacgcg
acccacgcctgccgggaacacctggaggccttcgaactgctggagcgctacagcggctat
ggggaggacagcgtccctcagctggaggacgtgtcccgtttcctgaaggagcggaccggc
ttccaactccggcctgtggctggcctgctgtctgcccgggacttcctggccagcctggcc
ttccgtgtgttccagtgcacacagtacatccgccatgcgtcctcgcccatgcactcccca
gagccggactgctgtcacgagctgctgggtcacgtgcctatgctggccaacaggaccttc
gctcagttctcccaggacatcggcctcgcgtccctgggggcctccgatgaagaaattgag
aagttgtctacgctgtactggttcacggtggagttcgggctgtgcaagcagaatggggag
ttgaaggcctacggggccggcctgctctcctcctacggggagctgctgcactccctgtcc
gcggagcccgaggtccggcccttcgaccccgacgcggcggcggtgcagccataccaggac
caaacctaccagccggtctacttcgtgtcggagagcttcagcgacgccagggacaagctt
aggagctacgcggcgcgcgtccggcgccccttctccgtgcgcctggacccgtatacgctg
gccgtggaggtgctggacagtcctcgctccctcgggcgctcgctggaggccgtccaggac
gagctgcaggcgctgggccacgcactgacctccatcggctag
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