Felis catus (domestic cat): 101089004
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Entry
101089004 CDS
T02385
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04148
Efferocytosis
fca04330
Notch signaling pathway
fca04668
TNF signaling pathway
fca05010
Alzheimer disease
fca05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101089004 (ADAM17)
04668 TNF signaling pathway
101089004 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101089004 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
101089004 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
101089004 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
fca01002
]
101089004 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
fca04090
]
101089004 (ADAM17)
Enzymes [BR:
fca01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
101089004 (ADAM17)
Peptidases and inhibitors [BR:
fca01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
101089004 (ADAM17)
CD molecules [BR:
fca04090
]
Proteins
101089004 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
101089004
NCBI-ProteinID:
XP_003984558
UniProt:
M3W8I1
LinkDB
All DBs
Position
A3:133473608..133526855
Genome browser
AA seq
828 aa
AA seq
DB search
MRQCLLFLTSVVPFVLAPRPPDGPGFGSPQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
QASTHLETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKDESEYAVKWQDFFTGHVV
GEPDSRVLAHIGDDDITVRINTDGAEYNIEPLWRLINDTTDKRMLVYKSEDIKNISRLQS
PKVCGYIKADNEELLPKGLVDREPPDELVHRVKRRADPNPMKNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQDVKPGERHYNM
AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCSSECMLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGNAADDTVCLDLGKCKDGKCVPFCEREQRLESCACNETDNSC
KVCCRDPSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMD
SASVRIVKPFPAPQTPGRPQPLQAAPAPPPPVPAAPKLDHQRMDTIQEDPSTDSHVDEDG
FEKDPFPNSSTAAKSFEDLTGRPVTRSEKASSFKLQRQNRVGSKETEC
NT seq
2487 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtgtctcctcttcctgaccagcgtggttcctttcgtgctggcgccgcgacct
ccggacgggccgggcttcggctccccgcagcgactcgaaaagcttgattctttactctca
gactacgatatcctctctttatccaatatccagcagcactcagtaagaaaacgggatcta
caagcctcaacacatttagaaacactactaactttttcagccttgaaaaggcattttaaa
ttatacctgacgtcaagtactgaacgcttttcccagaatttcaaagtcgtggtggtagat
ggtaaagacgaaagcgagtatgccgtcaagtggcaggacttctttactggacacgtggtc
ggtgagcctgactctagagttctagcccacataggagatgatgatattacagtaagaatc
aacacagatggggcagaatataatatagagccactttggagactaattaatgatactaca
gacaaaagaatgttagtttataaatctgaagatatcaagaatatttcacgtctgcagtct
ccaaaagtgtgtggttatataaaggcggataatgaagagttgcttccaaaagggctagta
gacagagagccacctgacgagcttgttcatcgggtgaagagaagagctgaccctaatccc
atgaagaacacgtgtaaattgttggtggtagcagatcatcgcttttacaaatacatgggc
agaggggaagagagcacaactacaaattacttgatagagcttattgacagagttgatgac
atctatcggaacacttcatgggacaacgcgggttttaaaggttacggaatacagatcgag
cagattcgcattctcaagtctccacaagatgtgaaacctggtgaaaggcactataacatg
gcaaaaagttatccaaatgaagaaaaggatgcttgggatgtgaagatgttgctagagcaa
tttagctttgatatagctgaggaagcatctaaagtctgcctcgcacatcttttcacctat
caagattttgatatgggaactcttggattagcttacgttggttctcccagagcaaacagc
cacggaggtgtttgtccaaaggcttactatagtccaattggaaagaagaatatctatttg
aatagtggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgac
ctggttacaactcatgaattgggacacaattttggagcagaacatgatccggatggccta
gcggaatgtgccccaaatgaggaccagggaggaaaatatgttatgtatcccatagcggtg
agtggagatcacgagaacaataagatgttttcaaactgcagtaagcagtccatctataag
accattgaaagtaaggcccaggagtgtttccaagaacgaagcaacaaagtgtgtgggaac
tccagggtggacgaaggagaggaatgcgatcctggcatcatgtacctgaacaacgacacc
tgctgcagcagcgaatgcatgctcaaggagggtgtgcagtgcagtgataggaacagtcct
tgctgtaaaaactgtcagttcgagactgcccagaagaagtgccaggaggctattaatgct
acctgcaaaggcgtgtcttactgcacaggtaacagcagcgagtgcccccctcccggaaac
gccgcagatgacacggtgtgcttggatcttggcaagtgtaaagatgggaagtgcgttccc
ttctgtgagagggagcagcggctggagtcctgtgcgtgtaacgagactgacaactcgtgc
aaggtgtgctgccgggacccctcgggccggtgcgtgccctatgtggacgctgaacaaaag
aacttattcttgaggaaaggaaagccctgtacggtgggattttgtgacatgaatggcaaa
tgtgagaaacgagtccaggacgtcatcgagcgattctgggacttcattgaccagttgagc
atcaacacttttgggaagtttttagcggacaacatcgtgggttccgtcctggttttctcc
ttgatattttggatccctttcagcattcttgtccattgtgtggacaagaaactggataag
cagtacgagtcgctgtctctgttccaccccagcaacgtggaaatgctaagcagcatggac
tcggcctcggttcgcatcgtcaagcccttccccgcgccccagacccccggccgcccgcag
cccctccaggccgcccccgcgccgcccccgccggtgcctgcggctcccaagctggaccac
cagcgcatggacacgatccaggaggaccccagcacggactcgcacgtggacgaggacggc
tttgagaaggacccctttcccaacagcagcacggccgccaagtcgttcgaggacctcacg
ggccggcccgtcacgaggagcgagaaggcctcgtccttcaaattgcagcgtcagaaccgc
gtgggcagcaaggagacggagtgctag
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