Felis catus (domestic cat): 493932 Help Entry 493932            CDS       T02385                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism fca  Felis catus (domestic cat) Pathway fca01524   Platinum drug resistance fca04010   MAPK signaling pathway fca04115   p53 signaling pathway fca04148   Efferocytosis fca04210   Apoptosis fca04215   Apoptosis - multiple species fca04623   Cytosolic DNA-sensing pathway fca04650   Natural killer cell mediated cytotoxicity fca04657   IL-17 signaling pathway fca04668   TNF signaling pathway fca04726   Serotonergic synapse fca04932   Non-alcoholic fatty liver disease fca04933   AGE-RAGE signaling pathway in diabetic complications fca04936   Alcoholic liver disease fca05010   Alzheimer disease fca05012   Parkinson disease fca05014   Amyotrophic lateral sclerosis fca05016   Huntington disease fca05020   Prion disease fca05022   Pathways of neurodegeneration - multiple diseases fca05132   Salmonella infection fca05133   Pertussis fca05134   Legionellosis fca05145   Toxoplasmosis fca05146   Amoebiasis fca05152   Tuberculosis fca05160   Hepatitis C fca05161   Hepatitis B fca05162   Measles fca05163   Human cytomegalovirus infection fca05164   Influenza A fca05165   Human papillomavirus infection fca05167   Kaposi sarcoma-associated herpesvirus infection fca05168   Herpes simplex virus 1 infection fca05169   Epstein-Barr virus infection fca05170   Human immunodeficiency virus 1 infection fca05200   Pathways in cancer fca05203   Viral carcinogenesis fca05205   Proteoglycans in cancer fca05206   MicroRNAs in cancer fca05210   Colorectal cancer fca05222   Small cell lung cancer fca05416   Viral myocarditis fca05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     493932 (CASP3)    04668 TNF signaling pathway     493932 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     493932 (CASP3)   09143 Cell growth and death    04210 Apoptosis     493932 (CASP3)    04215 Apoptosis - multiple species     493932 (CASP3)    04115 p53 signaling pathway     493932 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     493932 (CASP3)    04650 Natural killer cell mediated cytotoxicity     493932 (CASP3)    04657 IL-17 signaling pathway     493932 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     493932 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     493932 (CASP3)    05206 MicroRNAs in cancer     493932 (CASP3)    05205 Proteoglycans in cancer     493932 (CASP3)    05203 Viral carcinogenesis     493932 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     493932 (CASP3)    05222 Small cell lung cancer     493932 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     493932 (CASP3)    05161 Hepatitis B     493932 (CASP3)    05160 Hepatitis C     493932 (CASP3)    05164 Influenza A     493932 (CASP3)    05162 Measles     493932 (CASP3)    05168 Herpes simplex virus 1 infection     493932 (CASP3)    05163 Human cytomegalovirus infection     493932 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     493932 (CASP3)    05169 Epstein-Barr virus infection     493932 (CASP3)    05165 Human papillomavirus infection     493932 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     493932 (CASP3)    05133 Pertussis     493932 (CASP3)    05134 Legionellosis     493932 (CASP3)    05152 Tuberculosis     493932 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     493932 (CASP3)    05145 Toxoplasmosis     493932 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     493932 (CASP3)    05012 Parkinson disease     493932 (CASP3)    05014 Amyotrophic lateral sclerosis     493932 (CASP3)    05016 Huntington disease     493932 (CASP3)    05020 Prion disease     493932 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     493932 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     493932 (CASP3)    05416 Viral myocarditis     493932 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     493932 (CASP3)    04932 Non-alcoholic fatty liver disease     493932 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     493932 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     493932 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:fca01002]     493932 (CASP3) Enzymes [BR:fca01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      493932 (CASP3) Peptidases and inhibitors [BR:fca01002]  Cysteine peptidases   Family C14: caspase family    493932 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  493932 NCBI-ProteinID:  NP_001009338 UniProt:  Q8MJU1 LinkDB All DBs Position B1:complement(15537846..15559916) Genome browser AA seq 277 aa AA seqDB search MENSENSVDAKSIKNSETKIFHGSKSMDSGIYMDNSYKMDYPEMGLCIIINNKNFHESTG MPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVSREDHSKRSSFICVLLS HGEEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTED DIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHELEFMHILTRVN RKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacagtgaaaactcagtggatgcaaaatccattaaaaattccgaaacaaagatc ttccatggaagcaaatcaatggactctggaatatacatggacaacagttacaaaatggat taccctgaaatgggtttatgtataataattaataataagaactttcatgaaagtaccgga atgccgtctcggtctggtacagatgtggatgcggcgaacctccgagaaacattcacaaac ttaaaatacgaagtcaggaataaaaacgatcttacacgcgaacaaattgtggcgttgctg gacagtgtttctagagaagatcatagcaaaaggagcagttttatttgcgtgcttctaagc catggtgaagaaggaatcatttatggaacaaacggacctgttgacctgaaaaaattaaca ggtttcttcagaggggattattgtagaagtctaaccggcaaacccaaactcttcattatt caggcctgccgaggcacggaactggactgcggcattgagactgacagtggtaccgaggat gacatcgcctgtcagaaaataccagtggaggccgacttcttatatgcgtattccacagcc cctggttactactcctggcgaaattccaaggatggatcctggttcatccagtcactttgc tcgatgctcagactgtatgctcacgagcttgagttcatgcacattcttactcgggttaac cgaaaggtggcaacagaatttgagtccttttctcttgactctgcttttcatggaaagaaa cagattccatgtattgtgtctatgctcacaaaagaactatatttttatcactaa

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