KEGG   PATHWAY: gaf00531
Entry
gaf00531                    Pathway                                
Name
Glycosaminoglycan degradation - Gambusia affinis (western mosquitofish)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
gaf00531  Glycosaminoglycan degradation
gaf00531

Module
gaf_M00076  Dermatan sulfate degradation [PATH:gaf00531]
gaf_M00077  Chondroitin sulfate degradation [PATH:gaf00531]
gaf_M00078  Heparan sulfate degradation [PATH:gaf00531]
gaf_M00079  Keratan sulfate degradation [PATH:gaf00531]
Other DBs
GO: 0006027
Organism
Gambusia affinis (western mosquitofish) [GN:gaf]
Gene
122830251  si:dkey-72l14.3; glyco_hydro_56 domain-containing protein [KO:K01197] [EC:3.2.1.35]
122831723  hyal3; hyaluronidase-3 [KO:K01197] [EC:3.2.1.35]
122833793  hyal1; hyaluronidase-1 [KO:K01197] [EC:3.2.1.35]
122834194  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
122834509  hyaluronidase-2-like isoform X1 [KO:K01197] [EC:3.2.1.35]
122834513  hyaluronidase-2-like [KO:K01197] [EC:3.2.1.35]
122836089  spam1; hyaluronidase PH-20 [KO:K01197] [EC:3.2.1.35]
122836090  hyaluronidase-4 [KO:K01197] [EC:3.2.1.35]
122836091  hyal6; hyaluronoglucosaminidase 6 [KO:K01197] [EC:3.2.1.35]
122845225  gusb; beta-glucuronidase [KO:K01195] [EC:3.2.1.31]
122837431  iduronate 2-sulfatase-like [KO:K01136] [EC:3.1.6.13]
122827759  idua; alpha-L-iduronidase isoform X1 [KO:K01217] [EC:3.2.1.76]
122819373  arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
122819209  hpse; heparanase isoform X1 [KO:K07964] [EC:3.2.1.166]
122842393  hpse2; inactive heparanase-2 [KO:K07965] [EC:3.2.1.-]
122829630  sgsh; N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
122830110  hgsnat; heparan-alpha-glucosaminide N-acetyltransferase [KO:K10532] [EC:2.3.1.78]
122842269  si:dkey-192p21.6; heparan-alpha-glucosaminide N-acetyltransferase isoform X1 [KO:K10532] [EC:2.3.1.78]
122823243  naglu; alpha-N-acetylglucosaminidase isoform X1 [KO:K01205] [EC:3.2.1.50]
122822484  galns; N-acetylgalactosamine-6-sulfatase [KO:K01132] [EC:3.1.6.4]
122829908  glb1; beta-galactosidase [KO:K12309] [EC:3.2.1.23]
122819289  gnsb; glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b [KO:K01137] [EC:3.1.6.14]
122826641  gnsa; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
122819221  hexb; beta-hexosaminidase subunit beta isoform X1 [KO:K12373] [EC:3.2.1.52]
122835568  hexa; beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526   
G00711   
G00872  DWA-2
G01391   
G01945   
G01977   
G02632   
G09660   
G10008   
G10505  Hyaluronic acid
G12336   
G13034   
G13035   
G13036   
G13037   
G13038   
G13039   
G13040   
G13041   
G13042   
G13043   
G13073   
G13074   
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
gaf00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
gaf00533  Glycosaminoglycan biosynthesis - keratan sulfate
gaf00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   
LinkDB

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