Globicephala melas (long-finned pilot whale): 115846098
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Entry
115846098 CDS
T11080
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X4
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
gmf Globicephala melas (long-finned pilot whale)
Pathway
gmf04148
Efferocytosis
gmf04330
Notch signaling pathway
gmf04668
TNF signaling pathway
gmf05010
Alzheimer disease
gmf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
gmf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
115846098 (ADAM17)
04668 TNF signaling pathway
115846098 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
115846098 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
115846098 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
115846098 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
gmf01002
]
115846098 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
gmf04090
]
115846098 (ADAM17)
Enzymes [BR:
gmf01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
115846098 (ADAM17)
Peptidases and inhibitors [BR:
gmf01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
115846098 (ADAM17)
CD molecules [BR:
gmf04090
]
Proteins
115846098 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
115846098
NCBI-ProteinID:
XP_030700412
LinkDB
All DBs
Position
12:83451482..83503683
Genome browser
AA seq
830 aa
AA seq
DB search
MRQCVLFLSSLVPFVLAPRPPDEPGFGSPQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
QASTHLETLLIFSALKRHFKLYLTSSTERFSQNFKVVVVDGKDESEYPVKWQDFFSGHVV
GEPDSRVLAHIGDDDITIRINTDGVEYNVEPLWRLINDTKDKRVLVYKSEDIKNVSRLQS
PKVCGYIKADNEELLPKGLVGREPPDELVHRVKRRADPNPLKNTCKLLVVADHRFYRYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVRPGEKHFNM
AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPTGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCMLRPGVQCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGDAADDTVCLDLGKCKDGKCVPFCEREQRLESCACNETDNSC
KVCCRDPSGRCLPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWEFIDKLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQFESLSLFHPSNVEMLSSMD
SASVRIIKPFPAPPTPGRLQPPQPAPAVPPAPLVPVAPKLDHQRMDTIQEDPSTDSHADE
DGFEKDPFPNSSAAAKSFEDLTDHPVTRSEKPSSFKLQRQNRINSKETEC
NT seq
2493 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtgtgtcctcttcctgagcagcttggttcctttcgtgctggcgccgcgaccg
ccggacgagccgggcttcggctccccccagcgactcgaaaagcttgattctttgctctca
gactacgatatcctctctttatccaatatccaacagcactctgtaagaaaaagggatcta
caggcttcaacacacttagaaacactactaattttttcagccttgaaaaggcattttaaa
ttatacctgacatcaagtactgaacgcttttcccaaaatttcaaagtcgtggtggtagat
gggaaagatgaaagcgagtaccccgtcaaatggcaggacttcttcagtggacatgtggtt
ggtgagcctgactctagggttctagcccacataggagatgatgatatcacaataagaatc
aacacagatggggtggaatataatgtagagccactttggagactaattaatgatactaaa
gacaaaagagtgttagtttataaatctgaagatatcaagaatgtttcacgtttgcagtct
ccaaaagtgtgtggttatataaaggcggataatgaagagttgcttccaaaagggctggta
ggcagagagccacctgatgagcttgttcatcgggtgaagagaagagctgaccctaatccc
ctgaagaacacgtgtaaattattggtggtagcagatcatcgcttttacagatacatgggc
agaggggaagagagtacaactacaaactacttgatagagctaattgacagagttgatgac
atctatcggaacacttcatgggacaatgcaggttttaaaggttatggaatacagatagag
cagattcgcattctcaagtctccacaagaggtaagacctggtgaaaagcacttcaatatg
gcaaaaagttacccaaatgaagaaaaggatgcttgggacgtgaagatgctgctagagcaa
tttagctttgatatagctgaagaagcatctaaagtctgcctagcacatcttttcacctac
caagattttgatatgggaactcttggattagcttatgttggttctcccagagcaaacagt
catggaggtgtttgcccaaaggcttattatagtccaactggaaagaaaaatatctatttg
aatagtggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgac
ctcgttacaactcatgaattggggcacaattttggagcagaacacgatccagatggtcta
gcagaatgtgccccaaatgaggaccagggaggaaagtacgttatgtatcccatagctgtg
agtggcgatcacgagaacaataagatgttttcaaactgcagtaaacagtccatctataag
accattgaaagtaaggcccaggagtgttttcaagaacgcagcaacaaagtgtgcgggaac
tccagggtggacgagggggaggagtgtgaccccggcatcatgtacctgaacaatgacacc
tgctgcaacagtgactgcatgctgaggccgggcgtccagtgcagtgataggaacagtcct
tgctgtaaaaactgtcagttcgagacggcccagaagaagtgccaagaggccattaatgct
acgtgcaaaggcgtgtcttactgcacaggtaacagcagtgagtgcccccctcctggcgat
gctgccgacgacacggtgtgcttggatctcggcaagtgtaaagacggcaagtgtgtgccc
ttctgcgagcgggagcagaggctggagtcctgcgcgtgtaacgaaaccgacaactcgtgc
aaggtgtgctgcagggacccctcgggccgctgcctgccctatgtcgacgccgaacagaag
aacttatttttgaggaagggaaagccctgtacagtaggattttgtgacatgaatggcaaa
tgtgagaagcgagtgcaggatgtcattgagcggttctgggagttcattgacaagctgagc
atcaatactttcgggaagtttttagcagacaacatcgtaggctccgtcctagttttctcc
ttgatattttggattcctttcagcattctggtccattgtgtggataagaaactggacaag
cagtttgaatcgctgtctctgttccaccccagtaacgtcgagatgctcagcagcatggat
tccgcgtcggttcgcatcatcaagccctttcccgcgcccccgaccccgggccgcctgcag
cccccgcagcctgcccctgcggtgccccccgcgcctttggtgcctgtggccccaaagctg
gaccaccagcggatggacaccatccaggaggaccccagcacggattcgcacgccgacgag
gatggcttcgagaaggaccccttcccaaatagcagcgcagccgccaagtcgttcgaggac
ctcacggaccatccggtcaccagaagcgaaaagccctcgtcctttaagctgcagcgtcag
aaccgcattaacagcaaggaaaccgagtgctag
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